阴部神经封闭治疗特发性不稳定性膀胱

不稳定性膀胱所致尿频、尿急综合征在临床上治疗较困难,我们用阴部神经封闭治疗特发性不稳定性膀胱所致尿频、尿急综合征效果满意。报告如下。1临床资料1.1一般资料 1995年9月～1996年2月半年中,共收治20例不明原因的不稳定性膀胱所致尿频、尿急综合征患者。其中男性15例,妇性5例,平均年龄32.5岁(19～56岁),病程1～20年,平均5.2年。所有病例经病史、体检、尿常规、尿培养。

两种不同镇痛方法用于前列腺摘除术后的效果比较

摘要：目的探讨两种不同镇痛方法用于前列腺摘除术后的镇痛效果。方法所有患者木前30min肌注东莨菪碱0．3mg和鲁未那钠0．1g，于L2～3间隙穿刺，实施硬膜外麻醉。均采用爱朋牌术后镇痛泵，最大容量200mL。硬膜外自控镇痛（PCEA）组镇痛液方：用0．2％罗哌卡因＋2pg·mL^-1芬太尼．PCIA组20μg·mg^-1芬太尼配至20mL。术毕常规给予思丹司琼8mg静脉注射，在镇痛期间．常规监测SPO2、HR、RR、BP等。方法术后镇痛VAS评分：硬膜外组优于静脉组（P〈0．05）。不稳定性膀胱发生率硬膜外组低于静脉组（P〈0．05）。结论PCEA用于前列腺摘除术镇痛优于静脉自控镇痛（PCIA），且不稳定性膀胱发生率低。

Study of myogenic spontaneous contractile activities in the detrusor instability rats

Objective: To explore a myogenic basis of the spontaneous contractions on the rat bladder smooth muscle strip in a detrusor instability (DI) model in vitro, and to study a nerve blocker's cocktail affecting the spontaneous contractions as well as electrical stimulated contractile response. Methods: DI model rats were made by partial bladder outlet obstruction (BOO) and confirmed by the filling cystome-try. Detrusor strip was dissected from fresh bladder, fixed for an isometric tension trial. The contractions were recorded during electrical stimulation or exposure to some agents. Results: The cocktail diminished the nerve-mediated contractile response effectively in DI preparation. DI's spontaneous contractions remained during the presence of the cocktail with a significant change in its contractile amplitude. Conclusion : With the local nerve-concerned factors abolishment by the cocktail, the DI bladder preparations still have the spontaneous contractions, indicating a myogenic basis from themselves.