The research on the rock burst prediction was made on the basis of seismology,rock mechanics and the data from Dongguashan Copper Mine(DCM) ,the deepest metal mine in China.The seismic responses to mining in DCM were ...The research on the rock burst prediction was made on the basis of seismology,rock mechanics and the data from Dongguashan Copper Mine(DCM) ,the deepest metal mine in China.The seismic responses to mining in DCM were investigated through the analyses of the spatio-temporal distribution of hypocenters,apparent stress and displacement of seismic events,and the process of the generation of hazardous seismicity in DCM was studied in the framework of the theory of asperity in the seismic source mechanism.A method of locating areas with hazardous seismicity and a conceptual model of hazardous seismic nucleation in DCM were proposed.A criterion of rockburst prediction was analyzed theoretically in the framework of unstable failure theories,and consequently,the rate of change in the ratio of the seismic stiffness of rock in a seismic nucleation area to that in surrounding area,dS/dt,is defined as an index of the rockburst prediction.The possibility of a rockburst will increase if dS/dt>0,and the possibility of rock burst will decrease if dS/dt<0.The correctness of these methods is demonstrated by analyses of rock failure cases in DCM.展开更多
Objective: To demonstrate the functional changes of gap junctional mediation of intercellular communication in detrusor instability (DI) and its mechanisms. Methods: The function of gap junctional intercellular commun...Objective: To demonstrate the functional changes of gap junctional mediation of intercellular communication in detrusor instability (DI) and its mechanisms. Methods: The function of gap junctional intercellular communication in the cultured bladder detrusor cells was detected by fluorescence redistribution after photobleaching. Results: At the fourth minute after bleaching, the mean fluorescences recovery rates of DI group bladder detrusor cells were (35 791±0 836)%, that of control group (8 645±0 673)%. The mean fluorescence recovery rates of DI group were significantly higher than those of control group ( P <0 01). Conclusion: It shows that the increase of intercellular excitatory communication is one of the important reasons of pathogenesis of DI.展开更多
As the offshore engineering moving from shallow to deep waters, the foundation types for fixed and floating platforms have been gradually evolving to minimize engineering costs and structural risks in the harsh offsho...As the offshore engineering moving from shallow to deep waters, the foundation types for fixed and floating platforms have been gradually evolving to minimize engineering costs and structural risks in the harsh offshore environments. Particular focus of this paper is on the foundation instability and its failure mechanisms as well as the relevant theory advances for the prevailing foundation types in both shallow and deep water depths. Piles, spudcans, gravity bases, suction caissons, and plate anchors are detailed in this paper. The failure phenomena and mechanisms for each type of foundations are identified and summarized, respectively. The theoretical approaches along with sophisticated empirical solutions for the bearing capacity problems are then presented. The major challenges are from flow-structure-soil coupling processes, rigorous constitutive modeling of cyclic behaviors of marine sediments, and the spatial variability of soil properties for large-spreading structures. Further researches are suggested to reveal the instability mechanisms for underpinning the evolution of offshore foundations.展开更多
Non-volatile random-access memory（NVRAM） technology is maturing rapidly and its byte-persistence feature allows the design of new and efficient fault tolerance mechanisms. In this paper we propose the versionized pr...Non-volatile random-access memory（NVRAM） technology is maturing rapidly and its byte-persistence feature allows the design of new and efficient fault tolerance mechanisms. In this paper we propose the versionized process（Ver P）, a new process model based on NVRAM that is natively non-volatile and fault tolerant. We introduce an intermediate software layer that allows us to run a process directly on NVRAM and to put all the process states into NVRAM, and then propose a mechanism to versionize all the process data. Each piece of the process data is given a special version number, which increases with the modification of that piece of data. The version number can effectively help us trace the modification of any data and recover it to a consistent state after a system crash.Compared with traditional checkpoint methods, our work can achieve fine-grained fault tolerance at very little cost.展开更多
基金Project(2010CB732004) supported by the National Basic Research Program of ChinaProject(50490274) supported by the National Natural Science Foundation of China
文摘The research on the rock burst prediction was made on the basis of seismology,rock mechanics and the data from Dongguashan Copper Mine(DCM) ,the deepest metal mine in China.The seismic responses to mining in DCM were investigated through the analyses of the spatio-temporal distribution of hypocenters,apparent stress and displacement of seismic events,and the process of the generation of hazardous seismicity in DCM was studied in the framework of the theory of asperity in the seismic source mechanism.A method of locating areas with hazardous seismicity and a conceptual model of hazardous seismic nucleation in DCM were proposed.A criterion of rockburst prediction was analyzed theoretically in the framework of unstable failure theories,and consequently,the rate of change in the ratio of the seismic stiffness of rock in a seismic nucleation area to that in surrounding area,dS/dt,is defined as an index of the rockburst prediction.The possibility of a rockburst will increase if dS/dt>0,and the possibility of rock burst will decrease if dS/dt<0.The correctness of these methods is demonstrated by analyses of rock failure cases in DCM.
文摘Objective: To demonstrate the functional changes of gap junctional mediation of intercellular communication in detrusor instability (DI) and its mechanisms. Methods: The function of gap junctional intercellular communication in the cultured bladder detrusor cells was detected by fluorescence redistribution after photobleaching. Results: At the fourth minute after bleaching, the mean fluorescences recovery rates of DI group bladder detrusor cells were (35 791±0 836)%, that of control group (8 645±0 673)%. The mean fluorescence recovery rates of DI group were significantly higher than those of control group ( P <0 01). Conclusion: It shows that the increase of intercellular excitatory communication is one of the important reasons of pathogenesis of DI.
基金supported by the National Natural Science Foundation of China(Grant Nos.11232012,11372319 and 51309213)the National Key Basic Research Program of China(Grant No.2014CB046204)
文摘As the offshore engineering moving from shallow to deep waters, the foundation types for fixed and floating platforms have been gradually evolving to minimize engineering costs and structural risks in the harsh offshore environments. Particular focus of this paper is on the foundation instability and its failure mechanisms as well as the relevant theory advances for the prevailing foundation types in both shallow and deep water depths. Piles, spudcans, gravity bases, suction caissons, and plate anchors are detailed in this paper. The failure phenomena and mechanisms for each type of foundations are identified and summarized, respectively. The theoretical approaches along with sophisticated empirical solutions for the bearing capacity problems are then presented. The major challenges are from flow-structure-soil coupling processes, rigorous constitutive modeling of cyclic behaviors of marine sediments, and the spatial variability of soil properties for large-spreading structures. Further researches are suggested to reveal the instability mechanisms for underpinning the evolution of offshore foundations.
基金Project supported by the National High-Tech R&D Program(863)of China(Nos.2012AA01A301,2012AA010901,2012AA010303,and 2015AA01A301)the Program for New Century Excellent Talents in University,the National Natural Science Foundation of China(Nos.61272142,61402492,61402486,61379146,and 61272483)+1 种基金the Laboratory Pre-research Fund(No.9140C810106150C81001)the Open Project of the State Key Laboratory of High-End Server&Storage Technology(No.2014HSSA01)
文摘Non-volatile random-access memory（NVRAM） technology is maturing rapidly and its byte-persistence feature allows the design of new and efficient fault tolerance mechanisms. In this paper we propose the versionized process（Ver P）, a new process model based on NVRAM that is natively non-volatile and fault tolerant. We introduce an intermediate software layer that allows us to run a process directly on NVRAM and to put all the process states into NVRAM, and then propose a mechanism to versionize all the process data. Each piece of the process data is given a special version number, which increases with the modification of that piece of data. The version number can effectively help us trace the modification of any data and recover it to a consistent state after a system crash.Compared with traditional checkpoint methods, our work can achieve fine-grained fault tolerance at very little cost.
