针对传统实体关系抽取需要预先指定关系类型和制定抽取规则等无法胜任大规模文本的情况,开放式信息抽取(Open Information Extraction,OIE)在以英语为代表的西方语言中取得了重大进展,但对于汉语的研究却显得不足。为此,研究了在组块层...针对传统实体关系抽取需要预先指定关系类型和制定抽取规则等无法胜任大规模文本的情况,开放式信息抽取(Open Information Extraction,OIE)在以英语为代表的西方语言中取得了重大进展,但对于汉语的研究却显得不足。为此,研究了在组块层次标注基础上应用马尔可夫逻辑网分层次进行中文专利开放式实体关系抽取的方法。实验表明:以组块为出发点降低了对句子理解的难度,外层和内层组块可以统一处理,减少了工程代价;而且在相同特征条件下与支持向量机相比,基于马尔可夫逻辑网的关系抽取效果更理想,外层和内层识别结果的F值分别可达到77.92%和69.20%。展开更多
Aim： EPO （erythropoietin） is a hormone that stimulates the erythropoiesis and is mainly produced by the kidneys. In the early 1990s among the emerging biotech drugs, the recombinant human EPO （rhEPO） was the best...Aim： EPO （erythropoietin） is a hormone that stimulates the erythropoiesis and is mainly produced by the kidneys. In the early 1990s among the emerging biotech drugs, the recombinant human EPO （rhEPO） was the best-selling product worldwide, reaching nearly three billion dollars annually. The CIM （center of molecular immunology） produced and sold the rhEPO as commercial strategy to recover the investment made in its new facilities. This work summarizes the inventions that protect the innovative products developed by three Cuban institutions, starting from rhEPO, and the industrial property strategy followed by them. Methods： The information was obtained from the United States Patent, Trademark Office （USPTO） database, Patentscope, Espacenet, patent databases of Center for Pharmaceutical Research and Drug Development （CIDEM） and Cuban Industrial Property Office. Conclusions： The manufacturing process of CIM＇s EPO has its own patent family. From a manufacturing by product an innovative formulation protected by patent was obtained. There is a patent family around the nasal formulation and it continues enlarging. From a biosimilar pharmaceutical innovative products impacting on human health have been obtained.展开更多
Packaging is one of the most important methods of keeping the quality of food products for storage, transportation and end-use. The price of materials employed for packaging food has traditionally been high and used t...Packaging is one of the most important methods of keeping the quality of food products for storage, transportation and end-use. The price of materials employed for packaging food has traditionally been high and used to be more expensive than the food itself. Technological innovations made possible to produce packaging materials cheaply. One of these processes is known as co-extrusion. This technique makes a film with two or more layers with different plastics not laminating the layers together with an adhesive, eliminating the use of solvents and producing a film in just one step instead multiple steps. In this background, our paper relates to the evolution on packaging for foods by using patenting documents. A search for patent documents was performed on free patent databases using keywords and International Patent Classification （IPC） codes related to this technology. As results： （a） 17% of the 21,472 documents found are focused on multilayer packaging for food; （b） 12 countries hold more than 90% of patents （38% Japan; 23% The United States of America; 7% Canada and 6% Germany）; and, （c） two peaks were perceived in the period of 1992-1994 and 2003, and matches, respectively, the Persian Gulf （1990-1991） and Iraq Wars （2003-invasion of Iraq）, so the historical tendency is confirmed： ＂wars also generate scientific and technological innovations＂.展开更多
Biovitrum公司和Pharmacopeia Drug Discovery公司计划就鉴定和优化治疗代谢性疾病的小分子方面展开合作。Biovitrum公司将获得Pharmacopeia公司的专利小分子库及其药物发现专用技术，用于鉴定并优化这些小分子。Pharmacopeia公司将得...Biovitrum公司和Pharmacopeia Drug Discovery公司计划就鉴定和优化治疗代谢性疾病的小分子方面展开合作。Biovitrum公司将获得Pharmacopeia公司的专利小分子库及其药物发现专用技术，用于鉴定并优化这些小分子。Pharmacopeia公司将得到补偿其研究投资的启动资金并将获得完成临床前与临床等重大研究的款项以及这笔交易中任何药物商业化的版税。展开更多
文摘针对传统实体关系抽取需要预先指定关系类型和制定抽取规则等无法胜任大规模文本的情况,开放式信息抽取(Open Information Extraction,OIE)在以英语为代表的西方语言中取得了重大进展,但对于汉语的研究却显得不足。为此,研究了在组块层次标注基础上应用马尔可夫逻辑网分层次进行中文专利开放式实体关系抽取的方法。实验表明:以组块为出发点降低了对句子理解的难度,外层和内层组块可以统一处理,减少了工程代价;而且在相同特征条件下与支持向量机相比,基于马尔可夫逻辑网的关系抽取效果更理想,外层和内层识别结果的F值分别可达到77.92%和69.20%。
文摘Aim： EPO （erythropoietin） is a hormone that stimulates the erythropoiesis and is mainly produced by the kidneys. In the early 1990s among the emerging biotech drugs, the recombinant human EPO （rhEPO） was the best-selling product worldwide, reaching nearly three billion dollars annually. The CIM （center of molecular immunology） produced and sold the rhEPO as commercial strategy to recover the investment made in its new facilities. This work summarizes the inventions that protect the innovative products developed by three Cuban institutions, starting from rhEPO, and the industrial property strategy followed by them. Methods： The information was obtained from the United States Patent, Trademark Office （USPTO） database, Patentscope, Espacenet, patent databases of Center for Pharmaceutical Research and Drug Development （CIDEM） and Cuban Industrial Property Office. Conclusions： The manufacturing process of CIM＇s EPO has its own patent family. From a manufacturing by product an innovative formulation protected by patent was obtained. There is a patent family around the nasal formulation and it continues enlarging. From a biosimilar pharmaceutical innovative products impacting on human health have been obtained.
文摘Packaging is one of the most important methods of keeping the quality of food products for storage, transportation and end-use. The price of materials employed for packaging food has traditionally been high and used to be more expensive than the food itself. Technological innovations made possible to produce packaging materials cheaply. One of these processes is known as co-extrusion. This technique makes a film with two or more layers with different plastics not laminating the layers together with an adhesive, eliminating the use of solvents and producing a film in just one step instead multiple steps. In this background, our paper relates to the evolution on packaging for foods by using patenting documents. A search for patent documents was performed on free patent databases using keywords and International Patent Classification （IPC） codes related to this technology. As results： （a） 17% of the 21,472 documents found are focused on multilayer packaging for food; （b） 12 countries hold more than 90% of patents （38% Japan; 23% The United States of America; 7% Canada and 6% Germany）; and, （c） two peaks were perceived in the period of 1992-1994 and 2003, and matches, respectively, the Persian Gulf （1990-1991） and Iraq Wars （2003-invasion of Iraq）, so the historical tendency is confirmed： ＂wars also generate scientific and technological innovations＂.
文摘Biovitrum公司和Pharmacopeia Drug Discovery公司计划就鉴定和优化治疗代谢性疾病的小分子方面展开合作。Biovitrum公司将获得Pharmacopeia公司的专利小分子库及其药物发现专用技术，用于鉴定并优化这些小分子。Pharmacopeia公司将得到补偿其研究投资的启动资金并将获得完成临床前与临床等重大研究的款项以及这笔交易中任何药物商业化的版税。
