Objective： To explore the mechanism of anti-aging effect of acupuncture at Zusanli （ST 36）. Methods： Thirty mice of 28 weeks old were randomly divided into 3 groups： control group, model group and acupuncture gro...Objective： To explore the mechanism of anti-aging effect of acupuncture at Zusanli （ST 36）. Methods： Thirty mice of 28 weeks old were randomly divided into 3 groups： control group, model group and acupuncture group. Sub-acute aging model was established by subcutaneous injection of D-galactose. The activity of Superoxide Dismutase（SOD） and content of serum Malondialdehyde（MDA） were measured. Morphological changes of jejunal mucosa were observed with light microscope. Result： SOD activity in the acupuncture group was highest among the three groups, whereas, MDA content was the lowest. In the model group, the ratio of normal intestinal villus was decreased, the intestinal villus was shrunk, and there were more epithelial cells desquamated. In acupuncture group, there were less abnormal intestinal villus and epithelial cell. Conclusion： Acupuncture at Zusanli （ST 36） has an effect in resisting aging by increasing the activity of serum SOD, decreasing the MDA contents, and improving the intestinal villus.展开更多
Objective： To observe the effects of acupuncture and moxibustion on the skin histomorphology of senile mice. Methods： The subacute senile model of mouse was made by subcutaneous injection of D-galactose into the nec...Objective： To observe the effects of acupuncture and moxibustion on the skin histomorphology of senile mice. Methods： The subacute senile model of mouse was made by subcutaneous injection of D-galactose into the neck, then they were randomly allocated into an acupuncture group, a moxibustion group, a model group, and a blank group, and measured the content of malondialdehyde （MDA）, activity of glutathione peroxidase （GSH-Px）, and content of hydroxyproline （Hyp） in the skin tissue. Results： Acupuncture and moxibustion at Zusanli （ST 36） could decrease the content of MDA, enhance the activity of GSH-Px, and increase the content of Hyp in the skin tissue of senile mice. Conclusion： Acupuncture and moxibustion at Zusanli （ST 36） could delay the senescence progress of mice＇s skin.展开更多
文摘Objective： To explore the mechanism of anti-aging effect of acupuncture at Zusanli （ST 36）. Methods： Thirty mice of 28 weeks old were randomly divided into 3 groups： control group, model group and acupuncture group. Sub-acute aging model was established by subcutaneous injection of D-galactose. The activity of Superoxide Dismutase（SOD） and content of serum Malondialdehyde（MDA） were measured. Morphological changes of jejunal mucosa were observed with light microscope. Result： SOD activity in the acupuncture group was highest among the three groups, whereas, MDA content was the lowest. In the model group, the ratio of normal intestinal villus was decreased, the intestinal villus was shrunk, and there were more epithelial cells desquamated. In acupuncture group, there were less abnormal intestinal villus and epithelial cell. Conclusion： Acupuncture at Zusanli （ST 36） has an effect in resisting aging by increasing the activity of serum SOD, decreasing the MDA contents, and improving the intestinal villus.
基金National Key Laboratory Cultivation of the Laboratory on Combined Acupuncture and Medication,Higher Education of Jiangsu Province
文摘Objective： To observe the effects of acupuncture and moxibustion on the skin histomorphology of senile mice. Methods： The subacute senile model of mouse was made by subcutaneous injection of D-galactose into the neck, then they were randomly allocated into an acupuncture group, a moxibustion group, a model group, and a blank group, and measured the content of malondialdehyde （MDA）, activity of glutathione peroxidase （GSH-Px）, and content of hydroxyproline （Hyp） in the skin tissue. Results： Acupuncture and moxibustion at Zusanli （ST 36） could decrease the content of MDA, enhance the activity of GSH-Px, and increase the content of Hyp in the skin tissue of senile mice. Conclusion： Acupuncture and moxibustion at Zusanli （ST 36） could delay the senescence progress of mice＇s skin.
