The solid condensation of isopropylidene malonate with aromatic aldehydes were carried out by grinding at room temperature or heating at 110～120 ℃ to give 5 arylidene 2,2 dimethyl 1,3 dioxane 4,6 dione . Both condit...The solid condensation of isopropylidene malonate with aromatic aldehydes were carried out by grinding at room temperature or heating at 110～120 ℃ to give 5 arylidene 2,2 dimethyl 1,3 dioxane 4,6 dione . Both conditions afford the condensation high reaction activity. The yield of the product under grinding for 20 min followed by standing for 48 h at room temperature is 56%～80% and that by heating at 110～120 ℃ for 12 min is 55%～74%, respectively.展开更多
A general method for the synthesis of isopropylidene-5-alkyl-5-phenylemalonates via the reaction of phenyl (phenylethynyl )iodonium tosylate with isopropylidene 5-alkyl malonates in the presence of NaH/THF(or t-BuONa/...A general method for the synthesis of isopropylidene-5-alkyl-5-phenylemalonates via the reaction of phenyl (phenylethynyl )iodonium tosylate with isopropylidene 5-alkyl malonates in the presence of NaH/THF(or t-BuONa/t-BuOH, K2CO3/TEBA/CHCl3,K2CO3/18-Crown-6/THF ) is reported in this paper.展开更多
文摘The solid condensation of isopropylidene malonate with aromatic aldehydes were carried out by grinding at room temperature or heating at 110～120 ℃ to give 5 arylidene 2,2 dimethyl 1,3 dioxane 4,6 dione . Both conditions afford the condensation high reaction activity. The yield of the product under grinding for 20 min followed by standing for 48 h at room temperature is 56%～80% and that by heating at 110～120 ℃ for 12 min is 55%～74%, respectively.
文摘A general method for the synthesis of isopropylidene-5-alkyl-5-phenylemalonates via the reaction of phenyl (phenylethynyl )iodonium tosylate with isopropylidene 5-alkyl malonates in the presence of NaH/THF(or t-BuONa/t-BuOH, K2CO3/TEBA/CHCl3,K2CO3/18-Crown-6/THF ) is reported in this paper.
