Synthesis of α-hydroxy ketones by copper（Ⅰ）-catalyzed hydration of propargylic alcohols: CO2 as a cocatalyst under atmospheric pressure

Inexpensive and efficient Cu(Ⅰ) catalysis is reported for the synthesis of α-hydroxy ketones from propargylic alcohols, CO2, and water via tandem carboxylative cyclization and nucleophilic addition reaction. Notably, hydration of propargylic alcohols can be carried out smoothly under atmospheric CO2 pressure, generating a series of α-hydroxy ketones efficiently and selectively. This strategy shows great potential for the preparation of valuable α-hydroxy ketones by using CO2 as a crucial cocatalyst under mild conditions.

化学气相反应形成有机分子晶体的发现及制备

化学气相沉积法被广泛地用于硅、金刚石和其它无机薄膜的制备,而直接由化学气相反应生成有机分子晶体则较为罕见。本文报道了化学气相反应形成1-丙炔-1,3-二醇缩聚物分子晶体的过程及制备少量样品的方法。 1-丙炔-1,3-二醇属于简单有机化合物,如按与C≡C相连的羟基作为官能团进行分类,则该化合物应当是炔醇。