The interaction of morphine and cholinergic system was shown in previous studies. In the present study, we investigated whether morphine would interact with the cholinergic antagonists, scopolamine and atropine in a Y...The interaction of morphine and cholinergic system was shown in previous studies. In the present study, we investigated whether morphine would interact with the cholinergic antagonists, scopolamine and atropine in a Y-maze spatial recognition memory. Pre-test treatments of morphine (5, 1.5, 0.5 mg/kg), scopolamine (1, 0.1 mg/kg), atropine (0.5, 0.1 mg/kg) were used in the experiments, relatively high or low doses were paired respectively as co-administration measures. The results showed that co-administration of morphine 0.Smg/kg ~ scopolamine 0.1 mg/kg and morphine 0.5 mg/kg + atropine 0.1 mg/kg disturbed the inspective exploratory behavior (percent of arm duration) but not the inquisitive behavior (percent of arm visits) of the spatial memory retrieval, while the drugs didn't cause amnesia when single administered of the concerned low doses. Distinct interaction was found between scopolamine and morphine on increasing locomotor activity.展开更多
From the beginnings of Wahabism in the 18th century to the so called Islamic State of Iraq and the Levant (ISIL, ISIS) violence has occasionally been justified in the name of Islam, which is problematic for secular ...From the beginnings of Wahabism in the 18th century to the so called Islamic State of Iraq and the Levant (ISIL, ISIS) violence has occasionally been justified in the name of Islam, which is problematic for secular and traditional scholars alike. This paper demonstrates that there are three complex, interrelated causes for this violence: foreign military intervention, Salafi-Jihadism and a utopian state founded upon faith and justice, i.e. a caliphate.展开更多
The East Kuulun active fault zone, which lies in the valley of the Kuulun Mountains above an elevation of 4,000 meters, is an important active fault zone in the Northeast Qinghai-Xizang (Tibet) Plateau. The 1937, th...The East Kuulun active fault zone, which lies in the valley of the Kuulun Mountains above an elevation of 4,000 meters, is an important active fault zone in the Northeast Qinghai-Xizang (Tibet) Plateau. The 1937, the Tosonhu lake Ms7. 5 earthquake occurred in the eastern segment of the East Kuulun active fault zone. Four field investigations were launched on this seism in 1963, 1971, 1980, and between 1986 and 1990. However, due to different extents of the investigations, four different conclusions have been gained. Concerning the length aspect of the surface rupture zone of this earthquake, the unanimous consensus is that its eastern end lies in the west side of the main Ridge of the A 'nyemaqen Mountains, but opinions about the western end and the location of the macro-epicenter are different. Based on investigation and comprehensive study, a series of scientific problems like geometric and kinetic characteristics, the length of the rupture zone, the maximum sinistral horizontal displacement and the macroepicenter were re-evaluated. We believe that the total length of this earthquake's surface deformation zone is at least 240km; the western end of the zone is at the west of Wnsuwuwoguole; the maximum sinistral horizontal displacement is 8m to the west of Baerhalasha gully on the east side of Sanchakou; the maximum vertical displacement is 3.5m in the south of Sanchakou and the macro-epicenter is in Sanchakou.展开更多
基金National Natural Science Foundation of China(3077070030470553)~~
文摘The interaction of morphine and cholinergic system was shown in previous studies. In the present study, we investigated whether morphine would interact with the cholinergic antagonists, scopolamine and atropine in a Y-maze spatial recognition memory. Pre-test treatments of morphine (5, 1.5, 0.5 mg/kg), scopolamine (1, 0.1 mg/kg), atropine (0.5, 0.1 mg/kg) were used in the experiments, relatively high or low doses were paired respectively as co-administration measures. The results showed that co-administration of morphine 0.Smg/kg ~ scopolamine 0.1 mg/kg and morphine 0.5 mg/kg + atropine 0.1 mg/kg disturbed the inspective exploratory behavior (percent of arm duration) but not the inquisitive behavior (percent of arm visits) of the spatial memory retrieval, while the drugs didn't cause amnesia when single administered of the concerned low doses. Distinct interaction was found between scopolamine and morphine on increasing locomotor activity.
文摘From the beginnings of Wahabism in the 18th century to the so called Islamic State of Iraq and the Levant (ISIL, ISIS) violence has occasionally been justified in the name of Islam, which is problematic for secular and traditional scholars alike. This paper demonstrates that there are three complex, interrelated causes for this violence: foreign military intervention, Salafi-Jihadism and a utopian state founded upon faith and justice, i.e. a caliphate.
基金the National Science Foundation (Grant No.40474037) and by the Special Programfor Early-stage Investigation of National Major Basic Research of the Ministry of Science and Technology,China (Grant No.JC200016)
文摘The East Kuulun active fault zone, which lies in the valley of the Kuulun Mountains above an elevation of 4,000 meters, is an important active fault zone in the Northeast Qinghai-Xizang (Tibet) Plateau. The 1937, the Tosonhu lake Ms7. 5 earthquake occurred in the eastern segment of the East Kuulun active fault zone. Four field investigations were launched on this seism in 1963, 1971, 1980, and between 1986 and 1990. However, due to different extents of the investigations, four different conclusions have been gained. Concerning the length aspect of the surface rupture zone of this earthquake, the unanimous consensus is that its eastern end lies in the west side of the main Ridge of the A 'nyemaqen Mountains, but opinions about the western end and the location of the macro-epicenter are different. Based on investigation and comprehensive study, a series of scientific problems like geometric and kinetic characteristics, the length of the rupture zone, the maximum sinistral horizontal displacement and the macroepicenter were re-evaluated. We believe that the total length of this earthquake's surface deformation zone is at least 240km; the western end of the zone is at the west of Wnsuwuwoguole; the maximum sinistral horizontal displacement is 8m to the west of Baerhalasha gully on the east side of Sanchakou; the maximum vertical displacement is 3.5m in the south of Sanchakou and the macro-epicenter is in Sanchakou.