According to the recently developed single-trough floating machine with the world's largest volume(inflatable mechanical agitation flotation machine with volume of 320 m3) in China, the gas-fluid two-phase flow in...According to the recently developed single-trough floating machine with the world's largest volume(inflatable mechanical agitation flotation machine with volume of 320 m3) in China, the gas-fluid two-phase flow in flotation cell was simulated using computational fluid dynamics method. It is shown that hexahedral mesh scheme is more suitable for the complex structure of the flotation cell than tetrahedral mesh scheme, and a mesh quality ranging from 0.7 to 1.0 is obtained. Comparative studies of the standard k-ε, k-ω and realizable k-ε turbulence models were carried out. It is indicated that the standard k-ε turbulence model could give a result relatively close to the practice and the liquid phase flow field is well characterized. In addition, two obvious recirculation zones are formed in the mixing zones, and the pressure on the rotor and stator is well characterized. Furthermore, the simulation results using improved standard k-ε turbulence model show that surface tension coefficient of 0.072, drag model of Grace and coefficient of 4, and lift coefficient of 0.001 can be achieved. The research results suggest that gas-fluid two-phase flow in large flotation cell can be well simulated using computational fluid dynamics method.展开更多
According to our engineering research on satellite-borne laser retroreflector array, some suggestions are proposed on how to manufacture a new Apollo LLRA that can make us measure one illuminating point and unillumina...According to our engineering research on satellite-borne laser retroreflector array, some suggestions are proposed on how to manufacture a new Apollo LLRA that can make us measure one illuminating point and unilluminating area on the moon's surface. These suggestions are: to control the dihedral angle offset within ± 0.1″; to use the larger aperture of the transparent face of cube corner prisms; to investigate how to separate out Apollo's reflected laser from mixed beam hitting on the LLR system.展开更多
A 43-year-old man with a history of rheumatoid heart disease developed endocarditis.Blood culture showed endocarditis was caused by Kodamaea ohmeri and the susceptibility test showed the yeast species were susceptible...A 43-year-old man with a history of rheumatoid heart disease developed endocarditis.Blood culture showed endocarditis was caused by Kodamaea ohmeri and the susceptibility test showed the yeast species were susceptible to itraconazole,amphotericin B,and voriconazole,but susceptible-dose dependent to fluconazole,and resistant to 5-flucytosine.Treated with surgery and anti-fungi agents,the patient recovered from endocarditis.This is the first case of K.ohmeri fungemia found in Chinese from mainland.More and more evidence indicate that K.ohmeri is an important opportunistic pathogen for human beings.展开更多
This study evaluated the expression of N-acetyl-D-glucosamine, L-fucose, D-galactose and glucose/mannose on the cell wall surface of Aspergillus species using lectins and the in vitro antifungal activity of AMB （amph...This study evaluated the expression of N-acetyl-D-glucosamine, L-fucose, D-galactose and glucose/mannose on the cell wall surface of Aspergillus species using lectins and the in vitro antifungal activity of AMB （amphotericin B）, VOR （voriconazole） and ITC （itraconazole）. Con A （Concanavalin A）, WGA （wheat germ agglutinin）, UEA-I （Ulex europeus agglutinin I） and PNA （peanut agglutinin）, all conjugated with horseradish peroxidase, were used. For the susceptibility tests, sterilized fiat-bottomed 96-well microtitre plates were used and the procedures were followed of the Clinical and Laboratory Standard Institute. The inoculum was added to the wells with the tested drugs and the plates were incubated at 25 ℃ for 48 h before reading the results to determine the MIC （minimal inhibitory concentration） of AMB, VOR and ITC. All Aspergillus strains showed low MIC for AMB （0.031-1 μg/mL） and ITC （0.031-0.25μg/mL）. However, the isolates were less susceptible to VOR, for which the MIC ranged from 4 to 16 μg/mL. The results of this study indicate that the expression of N-acetyl-D-glucosamine and glucose/mannose on the cell wall surface of the Aspergillus species evaluated showed greater stability of expression in the fungal growth both in vitro and in parasitism.展开更多
基金Project(51074027)supported by the National Natural Science Foundation of China
文摘According to the recently developed single-trough floating machine with the world's largest volume(inflatable mechanical agitation flotation machine with volume of 320 m3) in China, the gas-fluid two-phase flow in flotation cell was simulated using computational fluid dynamics method. It is shown that hexahedral mesh scheme is more suitable for the complex structure of the flotation cell than tetrahedral mesh scheme, and a mesh quality ranging from 0.7 to 1.0 is obtained. Comparative studies of the standard k-ε, k-ω and realizable k-ε turbulence models were carried out. It is indicated that the standard k-ε turbulence model could give a result relatively close to the practice and the liquid phase flow field is well characterized. In addition, two obvious recirculation zones are formed in the mixing zones, and the pressure on the rotor and stator is well characterized. Furthermore, the simulation results using improved standard k-ε turbulence model show that surface tension coefficient of 0.072, drag model of Grace and coefficient of 4, and lift coefficient of 0.001 can be achieved. The research results suggest that gas-fluid two-phase flow in large flotation cell can be well simulated using computational fluid dynamics method.
文摘According to our engineering research on satellite-borne laser retroreflector array, some suggestions are proposed on how to manufacture a new Apollo LLRA that can make us measure one illuminating point and unilluminating area on the moon's surface. These suggestions are: to control the dihedral angle offset within ± 0.1″; to use the larger aperture of the transparent face of cube corner prisms; to investigate how to separate out Apollo's reflected laser from mixed beam hitting on the LLR system.
文摘A 43-year-old man with a history of rheumatoid heart disease developed endocarditis.Blood culture showed endocarditis was caused by Kodamaea ohmeri and the susceptibility test showed the yeast species were susceptible to itraconazole,amphotericin B,and voriconazole,but susceptible-dose dependent to fluconazole,and resistant to 5-flucytosine.Treated with surgery and anti-fungi agents,the patient recovered from endocarditis.This is the first case of K.ohmeri fungemia found in Chinese from mainland.More and more evidence indicate that K.ohmeri is an important opportunistic pathogen for human beings.
文摘This study evaluated the expression of N-acetyl-D-glucosamine, L-fucose, D-galactose and glucose/mannose on the cell wall surface of Aspergillus species using lectins and the in vitro antifungal activity of AMB （amphotericin B）, VOR （voriconazole） and ITC （itraconazole）. Con A （Concanavalin A）, WGA （wheat germ agglutinin）, UEA-I （Ulex europeus agglutinin I） and PNA （peanut agglutinin）, all conjugated with horseradish peroxidase, were used. For the susceptibility tests, sterilized fiat-bottomed 96-well microtitre plates were used and the procedures were followed of the Clinical and Laboratory Standard Institute. The inoculum was added to the wells with the tested drugs and the plates were incubated at 25 ℃ for 48 h before reading the results to determine the MIC （minimal inhibitory concentration） of AMB, VOR and ITC. All Aspergillus strains showed low MIC for AMB （0.031-1 μg/mL） and ITC （0.031-0.25μg/mL）. However, the isolates were less susceptible to VOR, for which the MIC ranged from 4 to 16 μg/mL. The results of this study indicate that the expression of N-acetyl-D-glucosamine and glucose/mannose on the cell wall surface of the Aspergillus species evaluated showed greater stability of expression in the fungal growth both in vitro and in parasitism.
