目的探讨骨折患者入院时创伤严重度评分(injury severity score,ISS)、严重创伤者生存概率(probability of suvival,PS)与临床相关因素的关系。方法回顾分析2001至2005年骨折患者163例,根据ISS分为轻伤(ISS<16分)组,重伤、严重伤组(...目的探讨骨折患者入院时创伤严重度评分(injury severity score,ISS)、严重创伤者生存概率(probability of suvival,PS)与临床相关因素的关系。方法回顾分析2001至2005年骨折患者163例,根据ISS分为轻伤(ISS<16分)组,重伤、严重伤组(ISS≥16分)。利用TRISS法统计每个患者的严重创伤者PS。对轻伤与重伤、严重伤间年龄、入院时间、入院时体温、PS、全身炎性反应综合征(SIRS)及入院后MAP、血常规、凝血、生化指标进行比较,并探讨ISS、PS与其他各因素的相关性。结果重伤、严重伤组PS、平均动脉压(MAP)、血红蛋白(HGB)、红细胞压积(HCT)、平均血小板体积(MPV)、大血小板比率(PLCR)、纤维蛋白原(Fbg)显著降低(P<0.05或<0.01),部分凝血活酶时间(APTT)、出血时间(BT)显著延长(P<0.05或<0.01),白细胞总数(WBC)、天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、肌酸磷酸激酶(CK)、乳酸脱氢酶(LDH)、α-羟丁酸脱氢酶(α-HBDH)显著升高(P<0.01),SIRS发生率显著增加(P<0.01),ISS与WBC、PS、MAP、血肌酐(Scr)、HCT相关(P<0.05或<0.01),PS与年龄、凝血酶原时间(PT)、白蛋白(ALB)、α-HBDH相关(P<0.05或<0.01)。结论对骨折患者进行血压、血常规、凝血功能、生化指标的观察,可判断病情并采取相应有利措施,减少并发症,改善预后。展开更多
目的探讨入院时不同程度创伤严重度评分(injury severity score,ISS)骨折患者的严重创伤者生存概率(probability of survival,PS)、全身炎症反应综合征(system ic inflam m atory response syndrom e,SIR S)发生率、平均动脉压(M AP)、...目的探讨入院时不同程度创伤严重度评分(injury severity score,ISS)骨折患者的严重创伤者生存概率(probability of survival,PS)、全身炎症反应综合征(system ic inflam m atory response syndrom e,SIR S)发生率、平均动脉压(M AP)、血红蛋白(H b)、红细胞压积(H C T)、白细胞总数(W BC)、中性粒细胞百分比(N EU T%)、血小板计数(PLT)、平均血小板分布宽度(PD W)、平均血小板体积(M PV)、大血小板比率(PLC R)、纤维蛋白原(Fbg)、总蛋白(TP)、白蛋白(ALB)、尿素氮(U R EA)、血肌酐(Scr)的变化及意义。方法回顾分析2001~2005年骨折患者226例,根据ISS分为轻度创伤组(ISS<16分)、中度创伤组(ISS16~24分)和严重创伤组(ISS≥25分)。利用TR ISS法统计每个患者的严重创伤者生存概率(PS)。对轻度创伤、中度创伤与严重创伤组间PS、SIR S发生率及入院后M AP、血常规、凝血、生化指标进行比较。结果中度创伤组M AP、H b、M PV、PLC R、Fbg、TP、ALB低于轻度创伤组,W BC、N EU T%、SIR S发生率、Scr高于轻度创伤组;严重创伤组M AP、PS、H C T、Fbg、TP、ALB低于中度创伤组,W BC、N EU T%、SIR S发生率高于中度创伤组,M AP、PS、H b、H C T、M PV、PLC R、Fbg、TP、ALB均低于轻度创伤组,W BC、N EU T%、SIR S发生率、U R EA及Scr高于轻度创伤组,差异有统计学意义。骨折患者Scr与ISS评分(r=0.273,P=0.000)、W BC(r=0.310,P=0.000)呈正相关,与PS(r=-0.202,P=0.003)、PD W(r=-0.165,P=0.018)、M PV(r=-0.193,P=0.005)、PLC R(r=-0.185,P=0.008)、Fbg(r=-0.172,P=0.017)、TP(r=-0.275,P=0.000)和ALB(r=-0.197,P=0.004)呈负相关。结论中度创伤组血压、血红蛋白、血小板体积、Fbg、血浆蛋白显著降低,W BC、N EU T%、SIR S发生率、Scr显著升高,严重创伤组除上述变化外,PS显著降低。Scr随ISS、W BC增加及PS、PD W、M PV、PLC R、Fbg、TP、ALB降低而升高,中度创伤组、严重创伤组肾功能发生改变,对骨折患者应加强肾功能检测。展开更多
Objective: To evaluate the application of injury severity score (ISS) to multiple injuries headed by spinal cord injury. Methods: The data of 55 cases (40 males and 15 females, aged 17-69 years, mean = 41 years...Objective: To evaluate the application of injury severity score (ISS) to multiple injuries headed by spinal cord injury. Methods: The data of 55 cases (40 males and 15 females, aged 17-69 years, mean = 41 years) of multiple injuries headed by spinal cord injury treated in our hospital from January 2000 to December 2004 were reviewed and analyzed with ISS (Version of AIS-2005 ) to explore their relationship. Results : The ISS values increased with the number of injured regions, so did the complications. The recovery rate was negatively related to ISS values. During the period of immunity observation, the patients with ISS 〉 25 could undergo planned operations safely. Conclusions: Treatment for multiple injuries headed by spinal cord injury closely depends on the general and local conditions of the patients. ISS may provide useful data for the choice of treatment methods.展开更多
Objective: To investigate a revision of the Trauma and Injury Severity Score (TRISS) weight coefficients in order to overcome the inference from foreign coefficients on Chinese trauma scoring. Methods: The data of ...Objective: To investigate a revision of the Trauma and Injury Severity Score (TRISS) weight coefficients in order to overcome the inference from foreign coefficients on Chinese trauma scoring. Methods: The data of 1 297 Chinese trauma patients were studied for trauma scoring with the Revised Trauma Score Injury Severity Score TRISS (RTS ISS TRISS) system to get a serial of new weight coefficients through analyzing a multivariation logical regression between the outcome and the injury severity. Results: ISS was higher but the Age Score and probability of survival (Ps) of the death group were lower than those of the survival group. New values of RTS ISS Age coefficients differed from the Major Trauma Outcome Study (MTOS) ones, through which the constant b 0 decreased its negative value, and ISS weight b 2 increased its negative value, but RTS weight b 1 and age weight b 3 changed with the trauma types. MTOSs values and new values of weight coefficients were used on 1 297 patients for prognosis by calculating Ps. The accuracy of new values ( 90.13 %) was a little higher than that of MTOSs (89.5%), with a promotion in specialization but a loss in sensitivity. Conclusions: A revision of TRISSs weight coefficients is either necessary or feasible. To achieve this purpose, a Chinese trauma database with large capacity is recommended.展开更多
文摘目的探讨骨折患者入院时创伤严重度评分(injury severity score,ISS)、严重创伤者生存概率(probability of suvival,PS)与临床相关因素的关系。方法回顾分析2001至2005年骨折患者163例,根据ISS分为轻伤(ISS<16分)组,重伤、严重伤组(ISS≥16分)。利用TRISS法统计每个患者的严重创伤者PS。对轻伤与重伤、严重伤间年龄、入院时间、入院时体温、PS、全身炎性反应综合征(SIRS)及入院后MAP、血常规、凝血、生化指标进行比较,并探讨ISS、PS与其他各因素的相关性。结果重伤、严重伤组PS、平均动脉压(MAP)、血红蛋白(HGB)、红细胞压积(HCT)、平均血小板体积(MPV)、大血小板比率(PLCR)、纤维蛋白原(Fbg)显著降低(P<0.05或<0.01),部分凝血活酶时间(APTT)、出血时间(BT)显著延长(P<0.05或<0.01),白细胞总数(WBC)、天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、肌酸磷酸激酶(CK)、乳酸脱氢酶(LDH)、α-羟丁酸脱氢酶(α-HBDH)显著升高(P<0.01),SIRS发生率显著增加(P<0.01),ISS与WBC、PS、MAP、血肌酐(Scr)、HCT相关(P<0.05或<0.01),PS与年龄、凝血酶原时间(PT)、白蛋白(ALB)、α-HBDH相关(P<0.05或<0.01)。结论对骨折患者进行血压、血常规、凝血功能、生化指标的观察,可判断病情并采取相应有利措施,减少并发症,改善预后。
文摘Objective: To evaluate the application of injury severity score (ISS) to multiple injuries headed by spinal cord injury. Methods: The data of 55 cases (40 males and 15 females, aged 17-69 years, mean = 41 years) of multiple injuries headed by spinal cord injury treated in our hospital from January 2000 to December 2004 were reviewed and analyzed with ISS (Version of AIS-2005 ) to explore their relationship. Results : The ISS values increased with the number of injured regions, so did the complications. The recovery rate was negatively related to ISS values. During the period of immunity observation, the patients with ISS 〉 25 could undergo planned operations safely. Conclusions: Treatment for multiple injuries headed by spinal cord injury closely depends on the general and local conditions of the patients. ISS may provide useful data for the choice of treatment methods.
文摘Objective: To investigate a revision of the Trauma and Injury Severity Score (TRISS) weight coefficients in order to overcome the inference from foreign coefficients on Chinese trauma scoring. Methods: The data of 1 297 Chinese trauma patients were studied for trauma scoring with the Revised Trauma Score Injury Severity Score TRISS (RTS ISS TRISS) system to get a serial of new weight coefficients through analyzing a multivariation logical regression between the outcome and the injury severity. Results: ISS was higher but the Age Score and probability of survival (Ps) of the death group were lower than those of the survival group. New values of RTS ISS Age coefficients differed from the Major Trauma Outcome Study (MTOS) ones, through which the constant b 0 decreased its negative value, and ISS weight b 2 increased its negative value, but RTS weight b 1 and age weight b 3 changed with the trauma types. MTOSs values and new values of weight coefficients were used on 1 297 patients for prognosis by calculating Ps. The accuracy of new values ( 90.13 %) was a little higher than that of MTOSs (89.5%), with a promotion in specialization but a loss in sensitivity. Conclusions: A revision of TRISSs weight coefficients is either necessary or feasible. To achieve this purpose, a Chinese trauma database with large capacity is recommended.