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基于真实世界研究探讨中、西医院使用藤黄健骨片治疗膝骨关节炎临床特征差异 被引量:3
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作者 李翔宇 李述文 +7 位作者 朱瑞征 贾雁 李瑞涵 符智虹 梁志 高帅 翁习生 陈卫衡 《世界中西医结合杂志》 2022年第11期2236-2240,共5页
目的探讨真实世界中、西医院使用藤黄健骨片治疗膝骨关节炎(Knee osteoarthritis,KOA)的临床特征差异,揭示不同类型医院中成药的用药规律。方法提取“藤黄健骨片治疗膝骨关节炎病例注册登记系统”中共计43家医院2505例使用藤黄健骨片治... 目的探讨真实世界中、西医院使用藤黄健骨片治疗膝骨关节炎(Knee osteoarthritis,KOA)的临床特征差异,揭示不同类型医院中成药的用药规律。方法提取“藤黄健骨片治疗膝骨关节炎病例注册登记系统”中共计43家医院2505例使用藤黄健骨片治疗膝骨关节炎的病历资料,根据医院性质分为中医院组(14家)和西医院组(29家),应用Excel 2019和SPSS 23.0统计学软件对两组患者人口统计学基本信息、就诊科室和接诊医师职称、既往史过敏史、藤黄健骨片口服剂量、临床表现进行基于频数与率的描述性分析和基于秩和检验的组间比较。结果中医院组1009例患者中男女性别比为1∶2.14,平均年龄(60.74±6.85)岁,西医院组1496例患者中男女性别比为1∶2.19,平均年龄(60.44±6.77岁)岁,差异无统计学意义(P>0.05);中医院组平均体质量指数(BMI)(24.26±2.74)高于西医院组(23.93±2.72),差异有统计学意义(P<0.05)。中医院组患者主要就诊科室为骨伤科(91.97%)、康复科(4.96%),接诊医师以主任医师(43.51%)为主;西医院组为骨科(86.56%)、疼痛科(5.55%),接诊医师以副主任医师(50.33%)为主,差异有统计学意义(P<0.05)。中医院组无合并疾病患者(747例,74.03%)比例低于西医院组(1245例,83.22%,P<0.05),而合并腰椎退行性病变、颈椎病及骨质疏松症的比例高于西医院组(P<0.05)。中医院组患者口服藤黄健骨片单次剂量为(3.14±1.15)片、单日总剂量为(7.16±2.64)片,均低于西医院组(3.87±1.39)片、(8.25±2.96)片(P<0.05)。中医院组患者中K-L分级0级16例(1.59%),K-L分级Ⅰ级69例(6.84%),K-L分级Ⅱ级533例(52.82%),K-L分级Ⅲ级391例(38.75%),K-L分级Ⅳ级0例;西医院组K-L分级0级31例(2.07%),K-L分级Ⅰ级81例(5.41%),K-L分级Ⅱ级833例(55.68%),K-L分级Ⅲ级544例(36.36%),K-L分级Ⅳ级7例(0.47%),两组比较,差异无统计学意义(P>0.05)。两组患者治疗后疼痛VAS评分、膝关节WOMAC评分均较治疗前降低,差异有统计学意义(P<0.05),且中医院组VAS、WOMAC评分均高于西医院组,差异有统计学意义(P<0.05)。中医院组关节肿胀好转率66.67%低于西医院组73.48%,关节怕冷好转率33.52%高于西医院组31.90%,腰膝酸软好转率43.37%高于西医院组33.73%。结论中、西医院两组患者临床特征组间差异不明显,中、西医院使用藤黄健骨片治疗膝骨关节炎均取得良好疗效。 展开更多
关键词 藤黄健骨片 膝骨关节炎 真实世界研究 中、西医院
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16 CASES OF SCALENUS SYNDROME TREATED BY MASSAGE AND ACUPOINT-INJECTION
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作者 彭浚宇 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1999年第3期218-220,共3页
Scalenus syndrome is a kind of thoracicoutlet syndrome. I treated 16 such cases withmassage in combination with acupointinjection from 1989-1996. The results weresatisfactory and introduced as follows.
关键词 Acupuncture Points ADULT Combined Modality Therapy FEMALE Humans INJECTIONS MASSAGE PROCAINE Thoracic Outlet Syndrome Vitamin B 12
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PROGRESS IN THE TREATMENT OF NERVE-ROOT-TYPE CERVICAL SPONDYLOSIS WITH CHINESE HERBAL DRUGS
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作者 张军 易金根 孙树椿 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1999年第3期227-233,共7页
With the highest morbidity rate, cervicalspondylosis of the nerve root type is mostcommon among various other types. It is fromthis type of cervical spondylosis that peoplebegan to know the disease. In recent years,co... With the highest morbidity rate, cervicalspondylosis of the nerve root type is mostcommon among various other types. It is fromthis type of cervical spondylosis that peoplebegan to know the disease. In recent years,conservative treatment for this type of cervicalspondylosis has been adopted by modernmedicine for most patients, while surgicaltreatment has also been used for a smallnumber of patients who were 展开更多
关键词 Cervical Vertebrae Drugs Chinese Herbal Humans Spinal Osteophytosis
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Characteristics and Advantages of Traditional Chinese Medicine in the Treatment of Acute Myocardial Infarction 被引量:25
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作者 刘红旭 王硕仁 +1 位作者 雷燕 尚菊菊 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2011年第4期269-272,共4页
Objective: To obtain epidemiological data on Traditional Chinese Medicine (TCM) therapeutic status of acute myocardial infarction (AMI) and to determine TCM characteristics and advantages to improve the level of TCM p... Objective: To obtain epidemiological data on Traditional Chinese Medicine (TCM) therapeutic status of acute myocardial infarction (AMI) and to determine TCM characteristics and advantages to improve the level of TCM prevention and treatment of AMI. Methods: Clinical epidemiology methods were used to register and survey the TCM therapeutic status of hospitalized AMI patients. In 2001, the Chinese Association of Integrative Medicine surveyed the therapeutic status of 3308 AMI patients hospitalized in 30 hospitals in Beijing and Shanghai from 2000-2001. The Beijing Collaborative Study Group on Therapeutic Status of Acute Myocardial Infarction (the Study Group) then conducted a 10-year-long register survey on hospitalized AMI patients in Third-grade A-Level TCM hospitals in Beijing. After 2002, the Study Group further surveyed the treatment conditions of AMI-hospitalized patients in 10 Second-grade A-Level TCM hospitals. The therapeutic status in 8 Third-grade A-Level Western medicine hospitals was surveyed in 2001 and 2005 as a control. In 2008, in cooperation with the China Association of Chinese Medicine, the Study Group further performed a survey at 26 Third-grade A-Level TCM hospitals nation-wide. Approximately 5000 cases were investigated to obtain authoritative data on the therapeutic status of AMI patients in TCM hospitals in China. Results: We found that Chinese herbal intravenous preparations may be beneficial in reducing the mortality of AMI. Major complications of AMI, such as heart failure and arrhythmia, were significantly less during the 10-year survey period. The mortality of hospitalized AMI patients showed a decline. TCM treatment was helpful for AMI patients in improving their quality of life. Ten-year dynamic monitoring showed that the ability to perform reperfusion and to use drugs appropriately, as well as an effort to carry out the Clinical Guidelines has made great progress in TCM hospitals. However, TCM hospitals still have some problems in treating AMI, including a lack of standardized TCM syndrome diagnosis, the need for syndrome differentiation and treatment standardization, and clinical skills in reperfusion and standardized drug treatment still need to be further improved. Compared with AMI patients in Western medicine hospitals during the same period, those in TCM hospitals had the following characteristics: they were admitted to hospital later; they were older when they had a heart attack; there were more females, they had more problems in their medical history, and they had more concomitant illnesses and complications. Therefore, the demographic baseline data were significantly different between AMI patients in TCM hospitals and those in Western medicine hospitals. This indicated that patients in TCM hospitals were more critical than those in Western medicine hospitals. Conclusions: TCM has special advantages in treating AMI. TCM hospitals are making continuous progress in standardized treatment of AMI, but further improvement is still required. AMI patients in TCM hospitals have some special characteristics, and their condition may be more critical. Further clinical research on TCM treatment of AMI is required. 展开更多
关键词 acute myocardial infarction Traditional Chinese Medicine therapeutic status
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