This paper reports two newly recorded species, lsohypsibius lunulatus Iharos, 1966 and lsohypsibiusprosostomus Thulin, 1928, of the genus lsohypsibius （Tardigrada; Hypsibiidae） from China. The specimens of lsohysibi...This paper reports two newly recorded species, lsohypsibius lunulatus Iharos, 1966 and lsohypsibiusprosostomus Thulin, 1928, of the genus lsohypsibius （Tardigrada; Hypsibiidae） from China. The specimens of lsohysibius lunulatus were collected from Taibai Mt （34°18′N, 107°42′E） at 2,500 m a.s.1, and those oflsohypsibius prosostomus from Taibai Mt （34°10′N, 107°35′E） at 2,000 m above sea level. All specimens are deposited at the College of Life Sciences, Shaanxi Normal University, China. A key to the Chinese species of lsohypsibius was also given.展开更多
Isotactic polypropylene （iPP） hollow fiber microporous membranes were prepared using thermally induced phase separation （TIPS） method. Di-n-butyl phthalate （DBP）, dioctyl phthalate （DOP）, and the mixed solvent...Isotactic polypropylene （iPP） hollow fiber microporous membranes were prepared using thermally induced phase separation （TIPS） method. Di-n-butyl phthalate （DBP）, dioctyl phthalate （DOP）, and the mixed solvent were used as diluents. The effect of α （DOP mass fraction in diluent） on the morphology and performance of the hollow fiber was investigated. With increasing α, the morphology of the resulting hollow fiber changes from typical cellular structure to mixed structure, and then to typical particulate structure. As a result, the permeability of the hollow fiber increases sharply, and the mechanical properties of the hollow fiber decrease obviously. It is suggested that the morphology and performances of iPP hollow fiber microporous membrane can be controlled via adjusting the compatibility between iPP and diluent.展开更多
Metabolomics has been widely used in the modern research of traditional Chinese medicine （TCM）. At the same time, the world is increasingly concerned about TCM, and many studies have been conducted to investigate di...Metabolomics has been widely used in the modern research of traditional Chinese medicine （TCM）. At the same time, the world is increasingly concerned about TCM, and many studies have been conducted to investigate different aspects of TCM. Among these studies, metabolomic approach has been implemented to facilitate TCM development. The current methods for TCM research are diverse, including nuclear magnetic resonance, gas chromatography-mass spectrometry, and liquid chromatographymass spectrometry. Using these techniques, some advantageous results have been obtained in the studies of TCM, such as diagnosis and treatment, quality control, and mechanisms of action. It is believed that the further development of metabo-lomic analytical techniques is benefcial to the modernization of TCM. This review summarizes potential applications of metabolomics in the area of TCM. Guidelines for good practice for the application of metabolomics in TCM research are also proposed, and the special role of metabolomics in TCM is highlighted.展开更多
Neurodermatitis, also called chronic simple lichen,is a common chronic inflammatory dennatosis characterized by paroxysmal severe itching and cutaneous lichenification. In clinic, this disease is often seen with the s...Neurodermatitis, also called chronic simple lichen,is a common chronic inflammatory dennatosis characterized by paroxysmal severe itching and cutaneous lichenification. In clinic, this disease is often seen with the symptoms caused by dampness,heat and blood stasis.展开更多
To promote efficient screening of active angiogenic drugs from traditional medicines, we constructed a humanembryonic kidney-293 cell model using vascular endothelial growth factor （VEGF） gene promoter as the drug t...To promote efficient screening of active angiogenic drugs from traditional medicines, we constructed a humanembryonic kidney-293 cell model using vascular endothelial growth factor （VEGF） gene promoter as the drug target. Inthis model, VEGF gene promoter may regulate the expression of the luciferase reporter gene by responding to thestimulation of drug molecules. This cell model allows rapid and efficient screening of vascular-inducing activecomponents from several drug monomer molecules. Furthermore, we used rat bone marrow mesenchymal stem cells（rMSCs） to conduct a preliminary study on the activity of alantolactone. Using simvastatin as a positive control, weinvestigated the effects of alantolactone on the expression of vascular-related cell marker molecules such as VEGF andα-smooth muscle actin （α-SMA） in rMSCs. According to our results, 0.1, 1, 3 and 5 μM of alantolactone upregulated thetranscriptional luciferase gene activity of VEGF promoter, and a significant difference from that in the control group wasobserved. Among them, 3μM of alantolactone showed the better effect than that of 3 μM of simvastatin （P = 0.036） andother concentrations of alantolactone and simvastatin showed similar effects. Compared with that in the control group,rMSCs induced with 1μM alantolactone for 3 days showed a significant increase in the relative mRNA expressions ofVEGF and α-SMA genes. However, these effect of 5 μM alantolactone were weaker than those of 5 μM simvastatin （P 〈0.05）; rMSCs treated with 1 μM alantolactone for 3 days showed brighter green fluorescence （FITC marker） of α-SMAand VEGF in situ expression than that observed in the control group and similar fluorescence intensity than that ofsimvastatin group in an immunoradiometric assay. The above results demonstrate the reliability of the highly efficientsystem for screening of active drug molecules and confirmed the vascular induction function of alantolactone at the geneand protein levels.展开更多
This paper introduced an integrated allocation model for distribution centers (DCs). The facility cost, inventory cost, transportation cost and service quality were considered in the model. An improved genetic algorit...This paper introduced an integrated allocation model for distribution centers (DCs). The facility cost, inventory cost, transportation cost and service quality were considered in the model. An improved genetic algorithm (IGA) was proposed to solve the problem. The improvement of IGA is based on the idea of adjusting crossover probability and mutation probability. The IGA is supplied by heuristic rules too. The simulation results show that the IGA is better than the standard GA(SGA) in search efficiency and equality.展开更多
The high order compact d if ference method is developed for solving the perturbation equations based on Navi er Stokes equations, and is used in studying complex evolution processes from w all negative pulse to the ...The high order compact d if ference method is developed for solving the perturbation equations based on Navi er Stokes equations, and is used in studying complex evolution processes from w all negative pulse to the turbulent coherent structure in the channel flow. Th is method contains three dimensional coupling difference scheme with high accur acy and high resolution, and the high order time splitting methods. Compared with the general spectral method, the method can be used to research turbule nt coherent structure under more general boundary conditions and in flow domains . In this paper, the generation and evolution of the turbulent coherent structur es ind uced by wall pulse in the channel flow are simulated, and the basic characterist ics and rules of the turbulent coherent structure are shown. Computational r esults indicate that a wall negative pulse is more convenient than the resonant three wave model.展开更多
The prediction of central bursting defects in the rod extrusion process through conical dies using the upper bound analysisis investigated. A kinematically admissible velocity field, including the radial and angular v...The prediction of central bursting defects in the rod extrusion process through conical dies using the upper bound analysisis investigated. A kinematically admissible velocity field, including the radial and angular velocity components, is proposed. A newcriterion is presented to predict the occurrence of the central bursting defects. Parameter bobt, which represents the risk probability ofcracking, is proposed. It is calculated using the shape of the boundary at the entrance by minimizing the total power dissipationduring the extrusion process. When bobt is equal to or greater than bcr, central bursting occurs. Furthermore, the quantitativerelationships between central bursting defects and process parameters （semi die angle, reduction in area and frictional factor） arestudied. The results show that the central bursting defects are affected primarily by the reduction in area and the friction factor. Thepresented criterion is verified by comparing with the FEM simulation data and the results of the published paper.展开更多
In recent years, China's energy demand and Greenhouse gas (GHG) emissions have grown very fast, quite an amount of which was exported as energy embodied in goods in international trade rather than consumed domesti...In recent years, China's energy demand and Greenhouse gas (GHG) emissions have grown very fast, quite an amount of which was exported as energy embodied in goods in international trade rather than consumed domestically. Starting from the concept of embodied energy, based on input-output energy analysis approach, in this paper the energy embodied in goods in international trade of China during the period from 2001 to 2006 is calculated. The results show that although China has become a net importer of petroleum since 1993, China is a net exporter of embodied energy due to international trade in goods. In 2002, the total amount of energy embodied in exported goods was about 410 million tce (ton of coal equivalent, hereinafter referred to as "tce"). Eliminating the amount of energy embodied in imported goods of about 170 million tce, the net export of embodied energy was about 240 million tce, accounting for 16% of the aggregate primary energy consumption of that very year in China, and the net export of embodied emissions was about 150 million tons of carbon. With the rapid growth of China's international trade, assuming no structural input-output changes of among sectors, in 2006 the net export of embodied energy went up to about 630 million tce, an increase of 162 % over 2002. In addition, this paper also analyzes the possible sources of error in calculation, and also discusses the policy implications according to the result of the calculation.展开更多
基金This study was supported by scientific research foundation project of Shaanxi Institute of Education (No. 07KJ37Q)
文摘This paper reports two newly recorded species, lsohypsibius lunulatus Iharos, 1966 and lsohypsibiusprosostomus Thulin, 1928, of the genus lsohypsibius （Tardigrada; Hypsibiidae） from China. The specimens of lsohysibius lunulatus were collected from Taibai Mt （34°18′N, 107°42′E） at 2,500 m a.s.1, and those oflsohypsibius prosostomus from Taibai Mt （34°10′N, 107°35′E） at 2,000 m above sea level. All specimens are deposited at the College of Life Sciences, Shaanxi Normal University, China. A key to the Chinese species of lsohypsibius was also given.
基金Supported by the National Natural Science Foundation of China （No.20236030）.
文摘Isotactic polypropylene （iPP） hollow fiber microporous membranes were prepared using thermally induced phase separation （TIPS） method. Di-n-butyl phthalate （DBP）, dioctyl phthalate （DOP）, and the mixed solvent were used as diluents. The effect of α （DOP mass fraction in diluent） on the morphology and performance of the hollow fiber was investigated. With increasing α, the morphology of the resulting hollow fiber changes from typical cellular structure to mixed structure, and then to typical particulate structure. As a result, the permeability of the hollow fiber increases sharply, and the mechanical properties of the hollow fiber decrease obviously. It is suggested that the morphology and performances of iPP hollow fiber microporous membrane can be controlled via adjusting the compatibility between iPP and diluent.
基金Supported by National Natural Science Foundation of China,Nos.81173500,81373930,81302905,81102556,and 81202639National Key Technology Research and Development Program of the Ministry of Science and Technology of China,Nos.2011BAI03B03,2011BAI03B06,and 2011BAI03B08+1 种基金National Key Subject of Drug Innovation,No.2009ZX09502-005Foundation of Heilongjiang University of Chinese Medicine,No.201209
文摘Metabolomics has been widely used in the modern research of traditional Chinese medicine （TCM）. At the same time, the world is increasingly concerned about TCM, and many studies have been conducted to investigate different aspects of TCM. Among these studies, metabolomic approach has been implemented to facilitate TCM development. The current methods for TCM research are diverse, including nuclear magnetic resonance, gas chromatography-mass spectrometry, and liquid chromatographymass spectrometry. Using these techniques, some advantageous results have been obtained in the studies of TCM, such as diagnosis and treatment, quality control, and mechanisms of action. It is believed that the further development of metabo-lomic analytical techniques is benefcial to the modernization of TCM. This review summarizes potential applications of metabolomics in the area of TCM. Guidelines for good practice for the application of metabolomics in TCM research are also proposed, and the special role of metabolomics in TCM is highlighted.
文摘Neurodermatitis, also called chronic simple lichen,is a common chronic inflammatory dennatosis characterized by paroxysmal severe itching and cutaneous lichenification. In clinic, this disease is often seen with the symptoms caused by dampness,heat and blood stasis.
文摘To promote efficient screening of active angiogenic drugs from traditional medicines, we constructed a humanembryonic kidney-293 cell model using vascular endothelial growth factor （VEGF） gene promoter as the drug target. Inthis model, VEGF gene promoter may regulate the expression of the luciferase reporter gene by responding to thestimulation of drug molecules. This cell model allows rapid and efficient screening of vascular-inducing activecomponents from several drug monomer molecules. Furthermore, we used rat bone marrow mesenchymal stem cells（rMSCs） to conduct a preliminary study on the activity of alantolactone. Using simvastatin as a positive control, weinvestigated the effects of alantolactone on the expression of vascular-related cell marker molecules such as VEGF andα-smooth muscle actin （α-SMA） in rMSCs. According to our results, 0.1, 1, 3 and 5 μM of alantolactone upregulated thetranscriptional luciferase gene activity of VEGF promoter, and a significant difference from that in the control group wasobserved. Among them, 3μM of alantolactone showed the better effect than that of 3 μM of simvastatin （P = 0.036） andother concentrations of alantolactone and simvastatin showed similar effects. Compared with that in the control group,rMSCs induced with 1μM alantolactone for 3 days showed a significant increase in the relative mRNA expressions ofVEGF and α-SMA genes. However, these effect of 5 μM alantolactone were weaker than those of 5 μM simvastatin （P 〈0.05）; rMSCs treated with 1 μM alantolactone for 3 days showed brighter green fluorescence （FITC marker） of α-SMAand VEGF in situ expression than that observed in the control group and similar fluorescence intensity than that ofsimvastatin group in an immunoradiometric assay. The above results demonstrate the reliability of the highly efficientsystem for screening of active drug molecules and confirmed the vascular induction function of alantolactone at the geneand protein levels.
文摘This paper introduced an integrated allocation model for distribution centers (DCs). The facility cost, inventory cost, transportation cost and service quality were considered in the model. An improved genetic algorithm (IGA) was proposed to solve the problem. The improvement of IGA is based on the idea of adjusting crossover probability and mutation probability. The IGA is supplied by heuristic rules too. The simulation results show that the IGA is better than the standard GA(SGA) in search efficiency and equality.
文摘The high order compact d if ference method is developed for solving the perturbation equations based on Navi er Stokes equations, and is used in studying complex evolution processes from w all negative pulse to the turbulent coherent structure in the channel flow. Th is method contains three dimensional coupling difference scheme with high accur acy and high resolution, and the high order time splitting methods. Compared with the general spectral method, the method can be used to research turbule nt coherent structure under more general boundary conditions and in flow domains . In this paper, the generation and evolution of the turbulent coherent structur es ind uced by wall pulse in the channel flow are simulated, and the basic characterist ics and rules of the turbulent coherent structure are shown. Computational r esults indicate that a wall negative pulse is more convenient than the resonant three wave model.
文摘The prediction of central bursting defects in the rod extrusion process through conical dies using the upper bound analysisis investigated. A kinematically admissible velocity field, including the radial and angular velocity components, is proposed. A newcriterion is presented to predict the occurrence of the central bursting defects. Parameter bobt, which represents the risk probability ofcracking, is proposed. It is calculated using the shape of the boundary at the entrance by minimizing the total power dissipationduring the extrusion process. When bobt is equal to or greater than bcr, central bursting occurs. Furthermore, the quantitativerelationships between central bursting defects and process parameters （semi die angle, reduction in area and frictional factor） arestudied. The results show that the central bursting defects are affected primarily by the reduction in area and the friction factor. Thepresented criterion is verified by comparing with the FEM simulation data and the results of the published paper.
基金sponsored by China Office of World Wide Fund for Nature(WWF)(No.:CN01010123514)
文摘In recent years, China's energy demand and Greenhouse gas (GHG) emissions have grown very fast, quite an amount of which was exported as energy embodied in goods in international trade rather than consumed domestically. Starting from the concept of embodied energy, based on input-output energy analysis approach, in this paper the energy embodied in goods in international trade of China during the period from 2001 to 2006 is calculated. The results show that although China has become a net importer of petroleum since 1993, China is a net exporter of embodied energy due to international trade in goods. In 2002, the total amount of energy embodied in exported goods was about 410 million tce (ton of coal equivalent, hereinafter referred to as "tce"). Eliminating the amount of energy embodied in imported goods of about 170 million tce, the net export of embodied energy was about 240 million tce, accounting for 16% of the aggregate primary energy consumption of that very year in China, and the net export of embodied emissions was about 150 million tons of carbon. With the rapid growth of China's international trade, assuming no structural input-output changes of among sectors, in 2006 the net export of embodied energy went up to about 630 million tce, an increase of 162 % over 2002. In addition, this paper also analyzes the possible sources of error in calculation, and also discusses the policy implications according to the result of the calculation.
