塞来昔布与中医电针疗法结合治疗腰椎间盘突出症的效果研究

目的:研究塞来昔布与中医电针疗法结合治疗腰椎间盘突出症(LDH)的效果。方法:选择2021年2月—2022年3月孝感市第一人民医院诊治的LDH患者110例,随机将其分为常规组(n=55)和研究组(n=55)。常规组采用常规治疗,服用塞来昔布胶囊,研究组在常规组治疗基础上加用中医电针疗法。观察两组腰椎功能、疼痛程度、生活质量及临床疗效情况。结果:研究组患者的干预总有效率(96.36%)明显比常规组患者(83.64%)高(P<0.05);相较于干预前,两组LDH患者在干预后的VAS评分均明显下降(P<0.05),且干预后研究组患者的VAS评分明显比常规组低(P<0.05);干预后,两组LDH患者的JOA评分相较于干预前改善较为明显(P<0.05),且研究组患者的JOA评分改善情况明显好于常规组(P<0.05);干预后,两组LDH患者的生活质量评分比干预前高(P<0.05),且研究组患者的生活质量评分比常规组高(P<0.05)。结论:塞来昔布与中医电针疗法结合治疗LDH患者疗效显著,提升其生活质量水平。

中西医结合干预胃部术后胃瘫患者抑郁状态的疗效观察

目的:观察中西医结合治疗胃部手术后胃瘫综合征患者的抑郁状态临床疗效,为临床治疗术后胃瘫综合征提供参考。方法:收集本院胃部手术后胃瘫患者30例,随机分为观察15例采用中西医结合疗法,对照组15例采用一般西医治疗,比较治疗前后患者汉密尔顿抑郁评分(HAMD)、汉密尔顿焦虑评分(HAMA)变化。结果:两组患者治疗前观察组、对照组抑郁评分分别为(21.4±8.2)(20.5±7.3),焦虑评分分别为:(22.6±5.0)(21.3±8.5);两组差异无统计学意义P>0.05,治疗2周后观察组、对照组抑郁评分分别为(10.4±2.8)(14.1±6.3),焦虑评分分别为:(13.1±2.8)(15.9±4.2)差异有统计学意义(P<0.05)。提示:观察组治疗方式在改善患者精神心理方面由于对照组。结论:中西医结合疗法能够显著得改善胃部手术后胃瘫患者的精神心理状况。

温针电针配合运动疗法与经皮电神经刺激治疗卒中后偏瘫肩痛临床研究

目的探讨温针电针配合运动疗法和经皮电神经刺激(transcutaneous electrical nervestimulation,TENS)治疗缺血性卒中后偏瘫肩痛的疗效。方法选取本院2016年5月-2019年3月符合入选标准的68例卒中后偏瘫肩痛患者,按随机数字表法分为2组,每组34例。2组均按指南给予西医常规疗法治疗,在此基础上对照组给予运动疗法和TENS,观察组在对照组治疗基础上加用温针电针。2组均治疗4周。采用VAS量表评估肩痛程度,采用Fugl-Meyer运动量表评估上肢运动功能,采用改良Barthel指数评估日常生活活动能力,采用肩手综合征评估量表(Shoulder Hand Syndrome Score,SHSS)评估患者感觉、远端水肿及运动情况,采用角度尺测量法测评肩关节前屈、后伸、外展、内旋、外旋的活动度,采用ELISA法检测hs-CRP、IL-6水平,评价临床疗效。结果治疗后,观察组VAS评分低于对照组(t=5.778,P<0.01),上肢Fugl-Meyer运动量表、改良Barthel指数评分高于对照组(t值分别为10.933、14.493,P值均<0.01);肩关节前屈、后伸、外展、内旋、外旋活动度均大于对照组(t值分别为16.251、12.006、29.001、16.008、24.003,P值均<0.01);感觉、远端水肿、运动评分均低于对照组(t值分别为5.331、5.172、6.221,P值均<0.01)。观察组总有效率为94.1%(32/34)、对照组为67.7%(23/34),2组比较差异有统计学意义(χ^2=6.087,P=0.014)。治疗后观察组血清hs-CRP[(10.55±1.72)mg/L比(13.81±2.79)mg/L,t=6.551]、IL-6[(9.31±1.56)μg/L比(11.78±1.90)μg/L,t=7.149]水平均低于对照组(P<0.01)。结论温针电针配合运动疗法与TENS可改善卒中后偏瘫肩痛患者的肩痛症状,降低炎性细胞因子水平,提高疗效。

Effects of Electroacupuncture at the Conception Vessel on Proliferation and Differentiation of Nerve Stem Cells in the Inferior Zone of the Lateral Ventricle in Cerebral Ischemia Rats

Objective： To observe the effects of electroacupuncture （EA） at the Conception Vessel on proliferation and differentiation of the nerve stem cells in the inferior zone of the lateral ventricle in cerebral ischemia rats. Methods： The model rats were prepared by occlusion of the middle cerebral artery for 2 hours and then by reperfusion. They were randomly divided into two groups： a control group and an EA group. Changes in differentiation and proliferation of the nerve stem cells were observed 7, 14 and 28 days after successful modeling. Results： As compared with the 7-day control group （C-7d group）, there was no significant difference （P〉0.05） in the numbers of 5-bromodeoxyuridine （Brdu） positive cells, Brdu/GFAP, Brdu/Nestin and Brdu/Nse double-labeled cells in the inferior zone of the lateral ventricle in the EA group 7 days after modeling. However, in the 14-day EA group （R-14d group） and the 28-day EA group （R-28d group）, the numbers of Brdu positive cells and Brdu/GFAE Brdu/Nestin, Brdu/Nse double-labeled cells significantly increased as compared respectively with the 14-day control （C-14d group） and the 28-day control （C-28d） group （P〈0.05 or P〈0.01）. Conclusions： EA at the Conception Vessel promotes differentiation and proliferation of the nerve stem cells in the inferior zone of the lateral ventricle in the cerebral ischemia rats, and may stimulate differentiation of the proliferous nerve stem cells towards the astrocvtes.

EFFECT OF ELECTROACUPUNCTURE ON ACONITINE-INDUCED VENTRICULAR TACHYARRHYTHIMIA

Objective: To investigate the effect of electroacupuncture (EA) on aconit ine-ind uced ventricular tachyarrhythmia. Methods: Twenty SD rats anesthe tized with chlo ral hydrate (300 mg/kg, i.p.) were evenly and randomly divided into control and EA groups. Ventricular arrhythmia was induced by intravenous infusion of 0.001% a conitine (i.v., 3.5 mg/kg, 0.4 mL/min). EA (4～16 Hz, 1～3 V) was applied to "N eiguan "(内关 PC 6) and "Jianshi"(间使 PC 5) for 30 min. ECG was recorded and analyz ed to deter mine ventricular premature beat (VPB), ventricular tachycardia (VT) and ventricu lar fibrillation (VF). Results: EA elevated the dose threshold o f aconitine-indu ced VF (P<0.05), delayed the occurrence of VT and VF (P <0.01), prolonged the sur vival time and reduced the mortality of rats treated with aconitine (P< 0.01). Conclusion: EA can suppress aconitine-induced ventricular tachyarr hythmia.

INFLUENCE OF ELECTROACUPUNCTURE ON ARTIFICIAL ABORTION- INDUCED SIDE EFFECTS

In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison with 45 artificial abortion women in the control group (who had not accepted EA treatment), EA possessed significant effects in relieving abdominal pain, reducing vaginal bleeding duration, lowering infection rate and infertility rate after artificial abortion operation.

CLINICAL STUDY ON TREATMENT OF VASCULAR DEMENTIA WITH ELECTROACUPUNCTURE OF "SISHENCHONG

Aim: To observe the therapeutic effect of electroacupuncture (EA) in the treatment of vascular dementia. Methods: A total of 46 cases of vascular dementia (VD) patients were divided into 3 classes according to the scores of the revised Hasegawa dementia scale (HDS), and then randomized into EA group (n=23) and medication (Nimodipine) group (n=23). The acupoints used were "Zhisanzhen" [Shenting (GV 24) and bilateral Benshen (GB 13)] and Sishenchong (EX HN 1) etc.. Scores of HDS, ability of daily life (ADL), neurofunctional defect and main symptoms were used as the indexes for assessing the therapeutic effect. Results: Following treatment, scores of HDS and ADL of two groups increased significantly, while those of neurofunctional defect and main symptoms decreased evidently (P<0.01), and the therapeutic effect of EA was obviously superior to that of medication (P<0.01). Conclusion: EA of "Zhisanzhen" and Sishenchong (EX HN 1) is a good approach for treatment of VD.

电针联合口服甲钴胺片治疗2型糖尿病合并轻中度腕管综合征临床研究

目的评价电针联合口服甲钴胺片治疗T2DM合并轻中度腕管综合征(carpal tunnel syndrome,CTS)的疗效。方法将符合入选标准的80例T2DM合并轻中度CTS患者采用随机数字表法分为2组,每组40例。治疗过程中,2组分别脱落2例,最终各有38例进入疗效统计。全部患者均积极控制血糖,对照组在此基础上口服甲钴胺片,治疗组在对照组基础上电针患侧大陵、内关,连续治疗6周。采用VAS量表评估疼痛程度,采用波士顿腕管问卷调查量表(Bonston Carpal Tunel Questionair,BCTQ)中的症状量表评估临床症状严重程度;应用肌电诱发电位仪检测感觉神经传导速度(sensory conduction velocity,SCV)、感觉神经动作电位(sensory nerve action potential,SNAP)的波幅及远端运动潜伏期(distal motor latency,DML)。评价临床疗效,记录不良事件。结果治疗组总有效率为81.6%(31/38)、对照组为60.5%(23/38),2组比较差异有统计学意义(χ^(2)=5.094,P=0.024)。治疗后,治疗组VAS、BCTQ评分均低于对照组(t值分别为2.639、2.790,P值分别为0.010、0.007);DML[(3.62±0.19)ms比(4.00±0.17)ms,t=68.891]低于对照组(P<0.01),SCV[(47.36±0.18)m/s比(42.34±0.14)m/s,t=97.163]、SNAP[(14.74±0.18)μV比(12.10±0.16)μV,t=51.434]高于对照组(P<0.01)。治疗期间,2组均未发生严重不良事件。结论电针联合口服甲钴胺片可减轻T2DM合并轻中度CTS患者的疼痛程度,改善腕关节症状。

Electroacupuncture and Proliferative Knee Osteoarthritis： A Report of 50 Cases

Fifty cases of knee osteoarthritis were treated with needling bilateral Neixiyan （Ex- LE 5）, Dubi （ST 35）, Ashi points, Yanglingquan （GB 34）, Yinlingquan （SP 9）, Zusanli （ST 36）, Liangqiu （ST 34）, Heding （Ex-LE 2）, and Sanyinjiao （SP 6）, among which Neixiyan （Ex-LE 5） and Heding （Ex-LE 2） were connected with electro-stimulator. And the result showed that 42 cases got recovery, 6 cases got better and 2 cases got no effect.