Objective Our objective was to analyze the traditional Chinese medicine(TCM)syndrome and treatment laws of diabetic kidney disease(DKD)and the action mechanism of high-frequency Chinese herbs in the treatment of DKD b...Objective Our objective was to analyze the traditional Chinese medicine(TCM)syndrome and treatment laws of diabetic kidney disease(DKD)and the action mechanism of high-frequency Chinese herbs in the treatment of DKD based on realworldstudy.MethodsThe data of patients with DKD who had been treated in the First Hospital Affiliated to Henan Universityof ChineseMedicine from January1,2014to December 31,2021 were retrospectively analyzed through the hospital information management system.The contents of the cases were statistically analyzed using IBM SPsS Statistics 25 software,and the laws of DKDtreatment were summarized.Network pharmacology and molecular docking were used to analyze the action mechanism of high-frequency Chinese herbs in the treatment of DKD.ResultsThe data of a total of 1,201 patients with DKD were included,involving 72 kinds of TCM syndromes.Nine disease nature elements and six disease location elements were extracted,involving 405 Chinese herbs.The top five high-frequency Chinese herbs were Baizhu(Atractylodis Macrocephalae Rhizoma),Fuling(Poria),Huangqi(Astragali Radix),Chuanxiong(Chuanxiong Rhizoma),and Danshen(Salviae Miltiorrhizae Radix et Rhizoma).Thirty kinds of Chinese herbs with the frequency of≥100 were mainly deficiency-tonifying herbs and blood-activating and stasis-eliminating herbs.The medicinal properties were mainly warm and mild,and the medicinal flavors were sweet and bitter mostly.For the meridian tropism,the main meridian tropism of these herbs is spleen meridian and lung meridian.The clustering method.展开更多
Objective： To make a bibliometric analysis and evaluation of acupuncture-moxibustion papers on moxibustion therapy published from 1954 to 2007, thus to reflect the diseases spectrum of moxibustion therapy and proper ...Objective： To make a bibliometric analysis and evaluation of acupuncture-moxibustion papers on moxibustion therapy published from 1954 to 2007, thus to reflect the diseases spectrum of moxibustion therapy and proper indications of moxibustion therapy objectively. Methods： Statistics were taken by a bibliometric analysis of the data from China Modern Acupuncture-moxibustion Information Databank. Results and Conclusion： The diseases spectrum of moxibustion therapy has 364 kinds of diseases. The most proper indications of moxibustion therapy are malposition, diarrhea, and colitis. The common proper indications are urinary incontinence and dysmenorrhea. The next common proper indications are knee osteoarthritis, temporomandibular joint disturbance syndrome, soft tissue injury, heel pain, asthma, urinary retention and herpes zoster. Diseases spectrum of moxibustion therapy varies with time.展开更多
基金supported by the National Key Research Project(2020YFE0201800)Henan Province Science and Technology Program for Tackling Key Problems(21210230347)2021 Postgraduate Scientifc Re-search Innovation Progrpm of Henan Universityof Chinese Medicine(2021KYCX008).
文摘Objective Our objective was to analyze the traditional Chinese medicine(TCM)syndrome and treatment laws of diabetic kidney disease(DKD)and the action mechanism of high-frequency Chinese herbs in the treatment of DKD based on realworldstudy.MethodsThe data of patients with DKD who had been treated in the First Hospital Affiliated to Henan Universityof ChineseMedicine from January1,2014to December 31,2021 were retrospectively analyzed through the hospital information management system.The contents of the cases were statistically analyzed using IBM SPsS Statistics 25 software,and the laws of DKDtreatment were summarized.Network pharmacology and molecular docking were used to analyze the action mechanism of high-frequency Chinese herbs in the treatment of DKD.ResultsThe data of a total of 1,201 patients with DKD were included,involving 72 kinds of TCM syndromes.Nine disease nature elements and six disease location elements were extracted,involving 405 Chinese herbs.The top five high-frequency Chinese herbs were Baizhu(Atractylodis Macrocephalae Rhizoma),Fuling(Poria),Huangqi(Astragali Radix),Chuanxiong(Chuanxiong Rhizoma),and Danshen(Salviae Miltiorrhizae Radix et Rhizoma).Thirty kinds of Chinese herbs with the frequency of≥100 were mainly deficiency-tonifying herbs and blood-activating and stasis-eliminating herbs.The medicinal properties were mainly warm and mild,and the medicinal flavors were sweet and bitter mostly.For the meridian tropism,the main meridian tropism of these herbs is spleen meridian and lung meridian.The clustering method.
基金supported by National Basic Research Program of China (973 Program, 2009CB522900)Shanghai Leading Academic Discipline Project
文摘Objective： To make a bibliometric analysis and evaluation of acupuncture-moxibustion papers on moxibustion therapy published from 1954 to 2007, thus to reflect the diseases spectrum of moxibustion therapy and proper indications of moxibustion therapy objectively. Methods： Statistics were taken by a bibliometric analysis of the data from China Modern Acupuncture-moxibustion Information Databank. Results and Conclusion： The diseases spectrum of moxibustion therapy has 364 kinds of diseases. The most proper indications of moxibustion therapy are malposition, diarrhea, and colitis. The common proper indications are urinary incontinence and dysmenorrhea. The next common proper indications are knee osteoarthritis, temporomandibular joint disturbance syndrome, soft tissue injury, heel pain, asthma, urinary retention and herpes zoster. Diseases spectrum of moxibustion therapy varies with time.
