AIM: To evaluate the therapeutic effect of the combined use of early short-term somatostatin and conventional integrated Chinese and Western medicine in treating severe acute pancreatitis. METHODS: Sixty patients with...AIM: To evaluate the therapeutic effect of the combined use of early short-term somatostatin and conventional integrated Chinese and Western medicine in treating severe acute pancreatitis. METHODS: Sixty patients with severe acute pancreatitis were divided at random into a somatostatin group and a basic treatment group. Both groups received integrated traditional Chinese and Western medicine without surgery. For patients in the somatostatin group, somatostatin was infused intravenously 250 μg/h for 72 h; other medications were the same as in the basic treatment group. In both groups, comparisons of therapeutic effectiveness were made in terms of morbidity of organic dysfunction and mortality rate, and severity of the disease according to serum levels of C-reaction protein, scores of acute physiology and chronic health evaluation (APACHE Ⅱ), and scores of Balthazar-CT. RESULTS: The indexes for C-reaction protein levels on the fourth and seventh clays, and APACHE II scores on the seventh day after treatment, were significantly improved in the somatostatin group than in the basic treatment group. The morbidity of organic dysfunction was lower in the somatostatin group than in the basic treatment group, although the difference was not statistically significant. There was no significant difference in mortality between the two groups. CONCLUSION: We conclude that combined traditional Chinese and Western medicines with an early short-term use of somatostatin can improve the condition of patients with severe acute pancreatitis.展开更多
Objective： To observe the therapeutic effect of medicine-separated moxibustion for primary dysmenorrhea and its influence on plasma hormone level. Methods. Ninety-six patients suffering from primary dysmenorrhea were...Objective： To observe the therapeutic effect of medicine-separated moxibustion for primary dysmenorrhea and its influence on plasma hormone level. Methods. Ninety-six patients suffering from primary dysmenorrhea were randomly and evenly divided into trealment group treated with medicine-separated moxibustion of Shenque （神阙 CV 8, 3-5 cones every time, beginning 1 week before onset of menstruation and stopping on the 3^rd day after onset, with 10 sessions being a therapeutic oourse, 3 courses all together）, and control group treated with oral administration of Yueyueshu （月月舒 menstruation-smoothing granule, 10 g/time, b.i.d, 3 courses altogether）. Menses prostaglandin E2（PGF2α） and plasma oxytocin （OT） during menstruation were determined by radioimmunoassay. Results; After the treatment, of the two 48 cases in treatment and control groups, 18 and 5 were cured, 24 and 9 had marked improvement in their symptoms, 6 and 26 had improvement, 0 and 8 failed in the treatment, with the total effective rates being 100. 096 and 83.3% respectively, the therapeutic effect of treatment group was markedly superior to that of control group （P〈0.05）. After the treatment, the contents of menses PGF2α in treatment group and plasma OT in both groups were significantly lower than those of pre-treatment （ P〈 0.01 ）. The therapeutic effect of moxibustion was significant- ly better than that of medication in lowering plasma OT. Conclusion： Medicine-separated moxibustion works well in treating primary dysmenorrhea, and moxibustion induced decrease of menses PGF2α and plasma OT may contribute to its effect in relieving dysmenorrhea.展开更多
Objective： To observe the therapeutic effect of acupuncture combined with medicines for acute cerebral infarction and to study its mechanism. Methods; A total of 80 acute cerebral infarction patients were evenly rand...Objective： To observe the therapeutic effect of acupuncture combined with medicines for acute cerebral infarction and to study its mechanism. Methods; A total of 80 acute cerebral infarction patients were evenly randomized into treabnent and control groups. Patients of treatment group were treated with acupuncture of Baihui （百会 GV 20）, Fengchi （风池 GB 20）, Jiquan （极泉 HT 1 ）, Neiiguen （ 内关 PC 6）, etc. and those of control group treated with conventional medicines as low molecular dextran, compound Red Sage injection, Citicolinum, etc. Scores of clinical neurological deficits, blood flow velocity peak （Vp） and mean blood flow velocity （Vm） of the bilateral internal carotid artery （ICA）, middle cerebral artery （MCA）, anterior cerebral artery （ACA）, posterior cerebral artery （PCA）, basilar artery （BA） and vertebral artery （VA） were detected with transcranial Doppler （TCO） were analyzed before and after treatment. Results： After 12 days＇ treatment, the neurological deficit scores in both treatment and control groups decreased significantly, and the difference values of the score of the former group was significantly bigger than these of the later group （P〈0.01）. Vp and Vm of all the detected arteries in treatment group and bilateral ACA, MCA and PCA of control group increased significantly in comparison with pre-treatment （P〈0.05, P〈0.01） ; and the difference values of Vm of bilateral MCA and VA （between post- and pre-treatment） of treatment group were significantly bigger than those of control group （P〈0.01）. Conclusion; The therapeutic effect of acupuncture combined with medication is significantly superior to that of simple medication in the treatment of acute cerebral infarction.展开更多
Objective： To observe the clinical therapeutic effect of acupuncture plus Chinese herbal medicines for ankylceing Methods： A total of 80 cases of AS patients were evenly and randomly divided into treatment group and...Objective： To observe the clinical therapeutic effect of acupuncture plus Chinese herbal medicines for ankylceing Methods： A total of 80 cases of AS patients were evenly and randomly divided into treatment group and control group. In treatment group, patients were treated with acupuncture of Jiaji （夹脊 EX-B 2） and oral administration of Yishen Tongdu Won （益肾通督丸,Bolus for Reinforcing the Kidney and Dredging Governor Vessesl） and those of control group treated with oral administration of Sulfasalazin （0.5 g, twice daily）. Before and after treatment, the thoracic-dilaion scale, Schober test, Bath ankylceing spondylitis disease activity index （BASDAI）, Bath ankylosing spondylitis functional index （BASFI）, erythrocyte sedimentation rate （ESR） and C-reaction protein （CRP） were detected separately. Results： After 6 months of treatment, of the both 40cases in treatment and control groups, 27 （67.5%） and 13 （32.5%） were improved remarkably, 11 （27.5%） and 16 （40.0%） effective, and 2 （5.0%） and 11 （27.5%） failed, with the effective rates being 95.0% and 72.5% separately. The therapeutic effect of treatment group was significantly superior to that of control group （P〈 0.05）. After treatment, the thoracicdilaion scale and Schober test values increased significantly （ P〈 0.05）, while BASDAI, BASFI, ESR and CRP lowered considerably （P〈0.01, P〈0.05）. Comparison between two groups indicated that after treatment, the decreased values of BASDAI, BASFI, ESR and CRP of treatment group were significantly lower than those of control group （ P〈 0.01 ）, while those of the thoracio-dilaion scale and Schober test of treatment group were significantly higher than those of control group （ P 〈 0.05, P 〈 0.01 ）. Results displayed that both acupuncture combined with Chinese drugs and Sulfasalazin could lower BASDAI, BASFI, ESR and CRP, raise the thoracic-dilaion scale and Schober test values considerably in AS patients, and the therapeutic effect of combined acupunclure and Chinese drugs was apparently superior to that of Westem medicine. Conclusion： Joint application of acupuncture and Chinese drugs is superior to Western medicine in the therapeutic effect for AS and has fewer side effects.展开更多
Lung cancer is one of the most common malignant tumors in the world. Non-small cell lung cancer （NSCLC） accounts for approximately 80% of lung cancer cases, and approximately 75% of patients are diagnosed in the mid...Lung cancer is one of the most common malignant tumors in the world. Non-small cell lung cancer （NSCLC） accounts for approximately 80% of lung cancer cases, and approximately 75% of patients are diagnosed in the middle and late stages. The treatment methods mainly include surgery, chemotherapy, radiotherapy, molecular targeted therapy, traditional Chinese medicine therapy, and immune therapy. We summarize the current status of lung cancer-related treatment options and targets.展开更多
Objective： To observe the therapeutic effect of plum-blossom needle tapping combined with intravenous drip of Acyclovir for herpes zoster. Methods; A total of 40 herpes zceter patients were randomized into acupunctur...Objective： To observe the therapeutic effect of plum-blossom needle tapping combined with intravenous drip of Acyclovir for herpes zoster. Methods; A total of 40 herpes zceter patients were randomized into acupuncture plus medication group （ n = 21 ） and medication group （ n = 19） which were treated respectively with topical plum-blossom needle tapping in the focus region combined with intravenous drip of Acyclovir （250 rng＋250 mL normal saline, twice daily） and simple intravenous drip of Acyclovir. Results： After treatment, of the 21 and 19 cases in acupuncture plus medication and medication groups, 18 （85.7%） and 10 （52.6%） were cured, 3 （ 14.3% ） and 7 （36.8%） had marked improvement, 0 （0） and 2 （ 10.5% ） failed, with the effective rates being 100,0% and 89,5% respectively. The cure duration of acupuncture plus medication end medication groups were （2.5± 1.0） days and （4.0±2.3） days separately. The therapeutic effect of the former group was significantly superior to that of the later group （P〈 0.05） and the duration of cure of acupuncture plus medication group was evidently shorter than that of medication group （P〈0.05）. Conclusion： The therapeutic effect of plum-blossom needle tapping plus Acyclovir is significantly superior to that of simple Acyclovir in relieving pain, promoting scabbing, and shortening the therapeutic duration.展开更多
OBJECTIVE: To compare the efficacy of integrated Chinese and Western Medicine with that of only Western Medicine for the treatment of malignant ascites.METHODS: All randomized controlled trials(January 2004 to March 2...OBJECTIVE: To compare the efficacy of integrated Chinese and Western Medicine with that of only Western Medicine for the treatment of malignant ascites.METHODS: All randomized controlled trials(January 2004 to March 2013) from the China National Knowledge Infrastructure Database, Chinese Biomedical Literature Database, and Wanfang Database were searched with keywords. Meta-analysis was conducted by combining the odds ratios of the individual studies. Review Manager 5.0 was used for the analysis.RESULTS: One thousand one hundred and fifty-six patients from 19 randomized controlled trails were included. Of them, 630 patients were treated with integrated Chinese and Western Medicine(the integrative group), and 526 patients were treated with Western Medicine alone(the control group). The Meta-analysis showed that the total effective rate was 78.73% in the integrated group, and 59.13% in the control group. The effective percentage was sig-nificantly higher in the integrative group than that of the control group [OR = 2.85, 95% CI(2.16,3.74),P < 0.01].CONCLUSION: The short-term curative effect in the integrative group was better than that in the control group. Integrative medicine may be beneficial for malignant ascites.展开更多
基金Supported by the Foundation of Sichuan Provincial Administration of Traditional Chinese Medicine, No.200213
文摘AIM: To evaluate the therapeutic effect of the combined use of early short-term somatostatin and conventional integrated Chinese and Western medicine in treating severe acute pancreatitis. METHODS: Sixty patients with severe acute pancreatitis were divided at random into a somatostatin group and a basic treatment group. Both groups received integrated traditional Chinese and Western medicine without surgery. For patients in the somatostatin group, somatostatin was infused intravenously 250 μg/h for 72 h; other medications were the same as in the basic treatment group. In both groups, comparisons of therapeutic effectiveness were made in terms of morbidity of organic dysfunction and mortality rate, and severity of the disease according to serum levels of C-reaction protein, scores of acute physiology and chronic health evaluation (APACHE Ⅱ), and scores of Balthazar-CT. RESULTS: The indexes for C-reaction protein levels on the fourth and seventh clays, and APACHE II scores on the seventh day after treatment, were significantly improved in the somatostatin group than in the basic treatment group. The morbidity of organic dysfunction was lower in the somatostatin group than in the basic treatment group, although the difference was not statistically significant. There was no significant difference in mortality between the two groups. CONCLUSION: We conclude that combined traditional Chinese and Western medicines with an early short-term use of somatostatin can improve the condition of patients with severe acute pancreatitis.
文摘Objective： To observe the therapeutic effect of medicine-separated moxibustion for primary dysmenorrhea and its influence on plasma hormone level. Methods. Ninety-six patients suffering from primary dysmenorrhea were randomly and evenly divided into trealment group treated with medicine-separated moxibustion of Shenque （神阙 CV 8, 3-5 cones every time, beginning 1 week before onset of menstruation and stopping on the 3^rd day after onset, with 10 sessions being a therapeutic oourse, 3 courses all together）, and control group treated with oral administration of Yueyueshu （月月舒 menstruation-smoothing granule, 10 g/time, b.i.d, 3 courses altogether）. Menses prostaglandin E2（PGF2α） and plasma oxytocin （OT） during menstruation were determined by radioimmunoassay. Results; After the treatment, of the two 48 cases in treatment and control groups, 18 and 5 were cured, 24 and 9 had marked improvement in their symptoms, 6 and 26 had improvement, 0 and 8 failed in the treatment, with the total effective rates being 100. 096 and 83.3% respectively, the therapeutic effect of treatment group was markedly superior to that of control group （P〈0.05）. After the treatment, the contents of menses PGF2α in treatment group and plasma OT in both groups were significantly lower than those of pre-treatment （ P〈 0.01 ）. The therapeutic effect of moxibustion was significant- ly better than that of medication in lowering plasma OT. Conclusion： Medicine-separated moxibustion works well in treating primary dysmenorrhea, and moxibustion induced decrease of menses PGF2α and plasma OT may contribute to its effect in relieving dysmenorrhea.
文摘Objective： To observe the therapeutic effect of acupuncture combined with medicines for acute cerebral infarction and to study its mechanism. Methods; A total of 80 acute cerebral infarction patients were evenly randomized into treabnent and control groups. Patients of treatment group were treated with acupuncture of Baihui （百会 GV 20）, Fengchi （风池 GB 20）, Jiquan （极泉 HT 1 ）, Neiiguen （ 内关 PC 6）, etc. and those of control group treated with conventional medicines as low molecular dextran, compound Red Sage injection, Citicolinum, etc. Scores of clinical neurological deficits, blood flow velocity peak （Vp） and mean blood flow velocity （Vm） of the bilateral internal carotid artery （ICA）, middle cerebral artery （MCA）, anterior cerebral artery （ACA）, posterior cerebral artery （PCA）, basilar artery （BA） and vertebral artery （VA） were detected with transcranial Doppler （TCO） were analyzed before and after treatment. Results： After 12 days＇ treatment, the neurological deficit scores in both treatment and control groups decreased significantly, and the difference values of the score of the former group was significantly bigger than these of the later group （P〈0.01）. Vp and Vm of all the detected arteries in treatment group and bilateral ACA, MCA and PCA of control group increased significantly in comparison with pre-treatment （P〈0.05, P〈0.01） ; and the difference values of Vm of bilateral MCA and VA （between post- and pre-treatment） of treatment group were significantly bigger than those of control group （P〈0.01）. Conclusion; The therapeutic effect of acupuncture combined with medication is significantly superior to that of simple medication in the treatment of acute cerebral infarction.
文摘Objective： To observe the clinical therapeutic effect of acupuncture plus Chinese herbal medicines for ankylceing Methods： A total of 80 cases of AS patients were evenly and randomly divided into treatment group and control group. In treatment group, patients were treated with acupuncture of Jiaji （夹脊 EX-B 2） and oral administration of Yishen Tongdu Won （益肾通督丸,Bolus for Reinforcing the Kidney and Dredging Governor Vessesl） and those of control group treated with oral administration of Sulfasalazin （0.5 g, twice daily）. Before and after treatment, the thoracic-dilaion scale, Schober test, Bath ankylceing spondylitis disease activity index （BASDAI）, Bath ankylosing spondylitis functional index （BASFI）, erythrocyte sedimentation rate （ESR） and C-reaction protein （CRP） were detected separately. Results： After 6 months of treatment, of the both 40cases in treatment and control groups, 27 （67.5%） and 13 （32.5%） were improved remarkably, 11 （27.5%） and 16 （40.0%） effective, and 2 （5.0%） and 11 （27.5%） failed, with the effective rates being 95.0% and 72.5% separately. The therapeutic effect of treatment group was significantly superior to that of control group （P〈 0.05）. After treatment, the thoracicdilaion scale and Schober test values increased significantly （ P〈 0.05）, while BASDAI, BASFI, ESR and CRP lowered considerably （P〈0.01, P〈0.05）. Comparison between two groups indicated that after treatment, the decreased values of BASDAI, BASFI, ESR and CRP of treatment group were significantly lower than those of control group （ P〈 0.01 ）, while those of the thoracio-dilaion scale and Schober test of treatment group were significantly higher than those of control group （ P 〈 0.05, P 〈 0.01 ）. Results displayed that both acupuncture combined with Chinese drugs and Sulfasalazin could lower BASDAI, BASFI, ESR and CRP, raise the thoracic-dilaion scale and Schober test values considerably in AS patients, and the therapeutic effect of combined acupunclure and Chinese drugs was apparently superior to that of Westem medicine. Conclusion： Joint application of acupuncture and Chinese drugs is superior to Western medicine in the therapeutic effect for AS and has fewer side effects.
文摘Lung cancer is one of the most common malignant tumors in the world. Non-small cell lung cancer （NSCLC） accounts for approximately 80% of lung cancer cases, and approximately 75% of patients are diagnosed in the middle and late stages. The treatment methods mainly include surgery, chemotherapy, radiotherapy, molecular targeted therapy, traditional Chinese medicine therapy, and immune therapy. We summarize the current status of lung cancer-related treatment options and targets.
文摘Objective： To observe the therapeutic effect of plum-blossom needle tapping combined with intravenous drip of Acyclovir for herpes zoster. Methods; A total of 40 herpes zceter patients were randomized into acupuncture plus medication group （ n = 21 ） and medication group （ n = 19） which were treated respectively with topical plum-blossom needle tapping in the focus region combined with intravenous drip of Acyclovir （250 rng＋250 mL normal saline, twice daily） and simple intravenous drip of Acyclovir. Results： After treatment, of the 21 and 19 cases in acupuncture plus medication and medication groups, 18 （85.7%） and 10 （52.6%） were cured, 3 （ 14.3% ） and 7 （36.8%） had marked improvement, 0 （0） and 2 （ 10.5% ） failed, with the effective rates being 100,0% and 89,5% respectively. The cure duration of acupuncture plus medication end medication groups were （2.5± 1.0） days and （4.0±2.3） days separately. The therapeutic effect of the former group was significantly superior to that of the later group （P〈 0.05） and the duration of cure of acupuncture plus medication group was evidently shorter than that of medication group （P〈0.05）. Conclusion： The therapeutic effect of plum-blossom needle tapping plus Acyclovir is significantly superior to that of simple Acyclovir in relieving pain, promoting scabbing, and shortening the therapeutic duration.
基金Supported by Key Projects of Beijing Municipal Science and Technology Commission(No.#D131100002213004)
文摘OBJECTIVE: To compare the efficacy of integrated Chinese and Western Medicine with that of only Western Medicine for the treatment of malignant ascites.METHODS: All randomized controlled trials(January 2004 to March 2013) from the China National Knowledge Infrastructure Database, Chinese Biomedical Literature Database, and Wanfang Database were searched with keywords. Meta-analysis was conducted by combining the odds ratios of the individual studies. Review Manager 5.0 was used for the analysis.RESULTS: One thousand one hundred and fifty-six patients from 19 randomized controlled trails were included. Of them, 630 patients were treated with integrated Chinese and Western Medicine(the integrative group), and 526 patients were treated with Western Medicine alone(the control group). The Meta-analysis showed that the total effective rate was 78.73% in the integrated group, and 59.13% in the control group. The effective percentage was sig-nificantly higher in the integrative group than that of the control group [OR = 2.85, 95% CI(2.16,3.74),P < 0.01].CONCLUSION: The short-term curative effect in the integrative group was better than that in the control group. Integrative medicine may be beneficial for malignant ascites.
