OBJECTIVE:Sub-optimal health status(SHS),in which a person's mind and body exists in a low-quality state of being between disease and health,has become a public health problem that cannot be ignored in China.SHS m...OBJECTIVE:Sub-optimal health status(SHS),in which a person's mind and body exists in a low-quality state of being between disease and health,has become a public health problem that cannot be ignored in China.SHS measurement presents a challenge to the academic fields.We developed and evaluated a questionnaire from the perspective of traditional Chinese medicine(TCM) that embodies the features of TCM syndrome diagnosis for measuring SHS in China.METHODS:The construction of the theoretical framework of the questionnaire was based on a literature review,an expert questionnaire survey and group interviews.The subscales and questionnaire items were screened through a pilot study using statistical means and qualitative analysis.Reliability tests that were used included test-retest reliability,Cronbach's α coefficient,split-half reliability;validity tests included content validity,criterion validity,discrimination validity and construct validity.RESULTS:The final questionnaire,the SHSQ-50,included 50 five-class quantifiable items that encompassed nine subscales:liver stagnation syndrome,liver-Qi deficiency syndrome,spleen-Qi deficiency syndrome,liver-fire syndrome,heart-fire syndrome,stomach-fire syndrome,heart-Qi deficiency syndrome,lung-Qi deficiency syndrome and dampness syndrome.Questionnaires were completed by 268 of the 288 SHS subjects(93.0%) and by 86 of the 94 healthy subjects(91.5%).The Cronbach α coefficients,split-half coefficients and stability coefficients ranged from 0.70 to 0.95,0.67 to 0.87 and 0.88 to 0.98,respectively,for the overall scores and subscales.The Wilcoxon rank test showed statistically significant differences in the subscales and overall scores between the SHS group and the healthy group(P<0.01).Twelve factors with an eigenvalue greater than one were extracted by factor analysis and merged into nine factors,for which the cumulative contribution rate was 63.63%.The nine factors were corresponded to the overall structure of the questionnaire.CONCLUSION:The SHSQ-50 is a reliable and valid instrument for measuring TCM syndrome diagnosis of SHS in China.展开更多
OBJECTIVE: Sui Zheng Shi Liang strategy (regulating prescription dosage with different syndromes) is an important part of syndrome differentiation and treatment in Traditional Chinese Medicine (TCM). Questionnaires we...OBJECTIVE: Sui Zheng Shi Liang strategy (regulating prescription dosage with different syndromes) is an important part of syndrome differentiation and treatment in Traditional Chinese Medicine (TCM). Questionnaires were given to doctors and patients to study the essential factors (indicators and timing) of Sui Zheng Shi Liang strategy in the treatment process of type 2 diabetes (T2DM). METHODS: Two questionnaires were designed for diabetes patients and their doctors. The questionnaires included the most important indicators for determining the patient's condition, the ability of TCM in treating T2DM, the length of time it takes for TCM to be effective, and when to adjust the prescription dosage.The frequency of answers was calculated, summarized, and analyzed after the survey. RESULTS: Twenty questionnaires from doctors and 90 questionnaires from patients were included in the analysis. Doctors and patients recognized thatTCM could decrease blood glucose, improve syndromes, and delay complications. Doctors were mainly concerned about glycosylated hemoglobin, while the patients were concerned about fasting plasma glucose for determining whether treatment was effective. Doctors also paid attention to changes in blood sugar and syndromes 2 weeks after medication was given as the indication to adjust the prescription dosage, while patients were concerned about these factors in 4 weeks.The prescription should be regulated when there are side effects or the medication is ineffective. CONCLUSION: The essential factor in the treatment process of T2DM in Sui Zheng Shi Liang strategy is that if fasting blood glucose level did not decrease after 4 weeks of treatment, the Chinese medicine prescription should be adjusted.展开更多
基金Supported by China National Funds for Distinguished Young Scientists(30825046)the National High Technology Research and Development Grant(863 program, 2008AA02Z406)the Program for Innovative Research Team at Beijing University of Chinese Medicine (2011CXTD-07)
文摘OBJECTIVE:Sub-optimal health status(SHS),in which a person's mind and body exists in a low-quality state of being between disease and health,has become a public health problem that cannot be ignored in China.SHS measurement presents a challenge to the academic fields.We developed and evaluated a questionnaire from the perspective of traditional Chinese medicine(TCM) that embodies the features of TCM syndrome diagnosis for measuring SHS in China.METHODS:The construction of the theoretical framework of the questionnaire was based on a literature review,an expert questionnaire survey and group interviews.The subscales and questionnaire items were screened through a pilot study using statistical means and qualitative analysis.Reliability tests that were used included test-retest reliability,Cronbach's α coefficient,split-half reliability;validity tests included content validity,criterion validity,discrimination validity and construct validity.RESULTS:The final questionnaire,the SHSQ-50,included 50 five-class quantifiable items that encompassed nine subscales:liver stagnation syndrome,liver-Qi deficiency syndrome,spleen-Qi deficiency syndrome,liver-fire syndrome,heart-fire syndrome,stomach-fire syndrome,heart-Qi deficiency syndrome,lung-Qi deficiency syndrome and dampness syndrome.Questionnaires were completed by 268 of the 288 SHS subjects(93.0%) and by 86 of the 94 healthy subjects(91.5%).The Cronbach α coefficients,split-half coefficients and stability coefficients ranged from 0.70 to 0.95,0.67 to 0.87 and 0.88 to 0.98,respectively,for the overall scores and subscales.The Wilcoxon rank test showed statistically significant differences in the subscales and overall scores between the SHS group and the healthy group(P<0.01).Twelve factors with an eigenvalue greater than one were extracted by factor analysis and merged into nine factors,for which the cumulative contribution rate was 63.63%.The nine factors were corresponded to the overall structure of the questionnaire.CONCLUSION:The SHSQ-50 is a reliable and valid instrument for measuring TCM syndrome diagnosis of SHS in China.
基金Supported by the National Basic Research Program (973Program, No. 2010CB530601)the National Natural Science Fund (No. 81274000)
文摘OBJECTIVE: Sui Zheng Shi Liang strategy (regulating prescription dosage with different syndromes) is an important part of syndrome differentiation and treatment in Traditional Chinese Medicine (TCM). Questionnaires were given to doctors and patients to study the essential factors (indicators and timing) of Sui Zheng Shi Liang strategy in the treatment process of type 2 diabetes (T2DM). METHODS: Two questionnaires were designed for diabetes patients and their doctors. The questionnaires included the most important indicators for determining the patient's condition, the ability of TCM in treating T2DM, the length of time it takes for TCM to be effective, and when to adjust the prescription dosage.The frequency of answers was calculated, summarized, and analyzed after the survey. RESULTS: Twenty questionnaires from doctors and 90 questionnaires from patients were included in the analysis. Doctors and patients recognized thatTCM could decrease blood glucose, improve syndromes, and delay complications. Doctors were mainly concerned about glycosylated hemoglobin, while the patients were concerned about fasting plasma glucose for determining whether treatment was effective. Doctors also paid attention to changes in blood sugar and syndromes 2 weeks after medication was given as the indication to adjust the prescription dosage, while patients were concerned about these factors in 4 weeks.The prescription should be regulated when there are side effects or the medication is ineffective. CONCLUSION: The essential factor in the treatment process of T2DM in Sui Zheng Shi Liang strategy is that if fasting blood glucose level did not decrease after 4 weeks of treatment, the Chinese medicine prescription should be adjusted.
