Purpose: This study compared the effects of pupil variation on light detection and temporal modulation across the central visual field.Methods:Light detection sensitivity (LDS) and low flickering frequency (6Hz) tempo...Purpose: This study compared the effects of pupil variation on light detection and temporal modulation across the central visual field.Methods:Light detection sensitivity (LDS) and low flickering frequency (6Hz) temporal modulation sensitivity (TMS) of 20 young subjects were measured from the central visual field of the right eyes using an automated perimeter (Medmont M600). The measurements were taken under 3 artificial pupils, I.e. 3 mm, 4.3 mm and 6 mm diameters.The sensitivities were grouped and averaged for different retinal eccentricities(3°, 6°, 10° and 15°).Results:TMS and LDS were reduced with increasing retinal eccentricities( P ＜ 0.001)and decreasing pupil diameters( P ＜ 0.001). TMS collected from all pupil diameters were significantly different from each other( P ＜ 0.001). Similarly, LDS under 3 mm pupil was statistically different from those of 4.3 mm and 6 mm(P ＜ 0.003). Comparison of the hills of vision showed that pupil variation resulted in significantly different slopes (P=0.001).The slopes were also found to be significantly different between TMS and LDS (P=0.012).Conclusions: The data showed that dilated pupil resulted in significantly higher sensitivities than those of smaller pupil for both visual functions. The difference in the slopes of hills of vision also suggested that the variation in retinal illumination affected the visual responses differently at various retinal eccentricitities for TMS and LDS.展开更多
病例1:患者,男,34岁,因"右眼视网膜脱离玻璃体切割术后1年复查"于2019年5月8日来宁波市第一医院就诊,发现眼底异常改变,无不适症状。专科检查:双眼视力1.0,眼压正常,双眼前节无异常,左眼底无异常改变。右眼底见中周部视网膜...病例1:患者,男,34岁,因"右眼视网膜脱离玻璃体切割术后1年复查"于2019年5月8日来宁波市第一医院就诊,发现眼底异常改变,无不适症状。专科检查:双眼视力1.0,眼压正常,双眼前节无异常,左眼底无异常改变。右眼底见中周部视网膜呈斑片状且颜色加深,与正常视网膜有明显分界线,透见脉络膜血管,炫彩照可见相应改变区呈暗红色斑片状(见图1)。炫彩光学相干断层扫描(OCT)可见暗红色区域的椭圆体带呈低反射信号(见图2)。自发荧光呈低荧光改变,眼底荧光血管造影(FFA)联合吲哚菁绿血管造影(Indocyanine green angiography,ICGA)晚期未见异常荧光渗漏(见图3,图4)。30-2中央视野见右眼生理盲点扩大,60-4周边视野见右眼鼻下方周边暗点(对应颞上方原视网膜裂孔);双眼视网膜电图(ERG)检查示:右眼与正常左眼相比无明显改变(见图5)。随访半年,眼底无明显改变(见图6)。展开更多
文摘Purpose: This study compared the effects of pupil variation on light detection and temporal modulation across the central visual field.Methods:Light detection sensitivity (LDS) and low flickering frequency (6Hz) temporal modulation sensitivity (TMS) of 20 young subjects were measured from the central visual field of the right eyes using an automated perimeter (Medmont M600). The measurements were taken under 3 artificial pupils, I.e. 3 mm, 4.3 mm and 6 mm diameters.The sensitivities were grouped and averaged for different retinal eccentricities(3°, 6°, 10° and 15°).Results:TMS and LDS were reduced with increasing retinal eccentricities( P ＜ 0.001)and decreasing pupil diameters( P ＜ 0.001). TMS collected from all pupil diameters were significantly different from each other( P ＜ 0.001). Similarly, LDS under 3 mm pupil was statistically different from those of 4.3 mm and 6 mm(P ＜ 0.003). Comparison of the hills of vision showed that pupil variation resulted in significantly different slopes (P=0.001).The slopes were also found to be significantly different between TMS and LDS (P=0.012).Conclusions: The data showed that dilated pupil resulted in significantly higher sensitivities than those of smaller pupil for both visual functions. The difference in the slopes of hills of vision also suggested that the variation in retinal illumination affected the visual responses differently at various retinal eccentricitities for TMS and LDS.
文摘病例1:患者,男,34岁,因"右眼视网膜脱离玻璃体切割术后1年复查"于2019年5月8日来宁波市第一医院就诊,发现眼底异常改变,无不适症状。专科检查:双眼视力1.0,眼压正常,双眼前节无异常,左眼底无异常改变。右眼底见中周部视网膜呈斑片状且颜色加深,与正常视网膜有明显分界线,透见脉络膜血管,炫彩照可见相应改变区呈暗红色斑片状(见图1)。炫彩光学相干断层扫描(OCT)可见暗红色区域的椭圆体带呈低反射信号(见图2)。自发荧光呈低荧光改变,眼底荧光血管造影(FFA)联合吲哚菁绿血管造影(Indocyanine green angiography,ICGA)晚期未见异常荧光渗漏(见图3,图4)。30-2中央视野见右眼生理盲点扩大,60-4周边视野见右眼鼻下方周边暗点(对应颞上方原视网膜裂孔);双眼视网膜电图(ERG)检查示:右眼与正常左眼相比无明显改变(见图5)。随访半年,眼底无明显改变(见图6)。
