中子俘获治疗癌症

简要介绍了中子俘获治疗（ＮＣＴ）的原理、发展历史及最新进展，指出成功地实现ＮＣＴ需要高质量的超热中子束、高选择性的ＮＣＴ药物、严格的剂量计算和测量及周密的治疗方案。本文对加速器和反应堆产生超热中子束的两种方法及质量要求作了较详细的讨论，对ＢＮＣＴ、ＧｄＮＣＴ、ＬｉＮＣＴ、ＵＮＣＴ及相关的药物进行了比较性评述，并对我国开展ＮＣＴ研究提出了建议。

Neutron Capture Therapy (NCT) & In-Hospital Neutron Irradiator (IHNI)——a new technology on binary targeting radiation therapy of cancer

BNCT is finally becoming ＂a new option against cancer＂. The difficulties for its development progress of that firstly is to improve the performance of boron compounds, secondly, it is the requirements of quantification and accuracy upon radiation dosimetry evaluation in clinical trials. Furthermore, that is long anticipation on hospital base neutron sources. It includes dedicated new NCT reactor, accelerator based neutron sources, and isotope source facilities. In ad- dition to reactors, so far, the technology of other types of sources for clinical trials is not yet completely proven. The In- Hospital Neutron lrradiator specially designed for NCT, based on the MNSR successfully developed by China, can be installed inside or near the hospital and operated directly by doctors. The Irradiator has two neutron beams for respective treatment of the shallow and deep tumors. It is expected to initiate operation in the end of this year. It would provide a safe, low cost, and effective treatment tool for the NCT routine application in near future.