根据套管井脉冲中子系统得到的密度——中子孔隙度分析泥质砂岩

已对康普乐公司的PND－S脉冲中子系统快中子非弹性散射产生的伽马射线衰减推导出的密度孔隙度进行了研究。这种套管井密度孔隙度的适用性在加拿大西部、德克萨斯湾区和蒙大拿州的砂泥岩层序油层分析中得到了证实。这些应用（与大井中子孔隙度结合)秋井眼条件下不允许裸眼井测井的井以及没有新的孔隙度测井资料或数据不可靠的老井提供孔隙度。可以根据充气孔隙度并使用下套管的探井中的测量值来确定低孔隙度层。在泥质砂岩分析中，中子孔隙度和SIGMA再加上这个新的密度测量值就可进行更全面的储层描述。对脉冲中子密度参数（LRHO），近／远热中子衰减比值（RATIO）曲线拟合来识别气层。测井分析实例中的脉冲中子密度孔隙度（IPHI）是通过确定一口井或油田的LRHO特性推导得出。在测井分析实例中同时使用了原型井眼补偿（BHC）算法、由该算法可得出描述特殊井眼尺寸和岩性的中子孔隙度（AIPN）及密度孔隙度（AIPO）。在几个测井实例中，对与裸眼井孔隙度的相关性进行了验证。一些典型的油藏描述和最优化问题的应用实例说明了这些测量值在套管井油层分析中的适用性。

费米子系统的相变

本文给出一个中子系统热状态方程。讨论了该系统的相变。得出相变的临界温度T_c=1.034×10^(11)K,有效质量是M~*/M=0.973。

Boehmeria nivea var. strigosa (Urticaceae), a new variety from Southwest China

Boehmeria nivea var.strigosa Zeng Y.Wu&Y.Zhao,a new variety of B.nivea(Urticaceae)from Southwest China,is here described based on evidence from morphology and molecular phylogeny.This new variety is mainly characterized by its green abaxial leaf blade,partly connate stipules,and densely patent strigose hairs on stems and potioles.The phylogenetic analysis based on rbc L,nrDNA and rbc L+nrDNA datasets,revealed that all individuals of B.nivea var.strigosa formed a monophyletic group.The conservation status of B.nivea var.strigosa is assessed as“Near Threatened”(NT)according to IUCN evaluation criteria.The discovery of this new variety is not only crucial for the taxonomy of ramie,but also provides reference for the exploration and utilization of ramie.

Roles of NF-κB in central nervous system damage and repair

NF-κB family is a kind of nuclear factors in B lymphocyte that can bind to the immunoglobulin κ-chain enhancer and enhance transcriptional activity. NF-κB/Rel proteins, as a dimeric transcription factor, control the expression of genes that regulate a broad range of biological processes through canonical and non-canonical pathways. In the central nervous system, NF-κB controls inflammatory reactions and the apoptotic cell death following nerve injury. It also contributes to the infarction and cell death in stroke models and patients. However, NF-κB is essential for neurosurvival as well. NF-κB activation is a part of recovery process that may protect neurons against oxidative-stresses or brain ischemia-induced apoptosis and neurodegeneration. Inhibition of NF-κB may reduce its neuroprotection activity. Hence the dual opposite effects of NF-κB on cells. The ultimate survival or death of neurons depends on which, where and when the NF-κB factors are activated.

Molecular actions guiding neural regeneration in planarian

Planarian is among the simplest animals that possess a centralized nervous system （CNS）, and its neural regenera- tion involves the replacement of cells lost to normal ＇wear and tear＇ （cell turnover）, and/or injury. In this review, we state and discuss the recent studies on molecular control of neural regeneration in planarians. The spatial and temporal expression patterns of genes in intact and regenerating planarian CNS have already been described relatively clearly. The bone morphogenetic protein （BMP） and Wnt signaling pathways are identified to regulate neural regeneration. During neural regeneration, conserved axon guidance mechanisms are necessary for proper wiring of the nervous system. In addition, apoptosis may play an important role in controlling cell numbers, eliminating unnecessary tissues or cells and remodeling the old tissues for regenerating CNS. The bilateral symmetry is established by determination of anterior-posterior （A-P） and dorsal-ventral （D-V） patterns. Moreover, neurons positive to dopamine, serotonin （5-HT）, and gamma-aminobutyric acid （GABA） have been detected in planarians. Therefore, planarians present us with new, experimentally accessible contexts to study the molecular actions guiding neural regeneration.

科技创新与科技金融协同度模型及其应用研究

随着我国改革开放的不断深入,提高自主创新能力,建设创新型国家已成为必然发展趋势。财政部与监证会等部门都明确提出支持科技创新与科技金融协同的方式,这样能够为经济发展造就更有利的机遇。本文笔者针对科技创新与科技金融协同度模型应用展开了相关的探讨,首先对科技创新和科技金融协同度模型机理进行了分析,其次对其模型构建的复合系统协同度模型与中子系统有序度模型加以论述,主要宗旨是实现科技创新与科技金融的协同度,从而为我国科学技术的发展打下坚实的根基。

BCL-XL regulates TNF-α-mediated cell death independently of NF-κB, FLIP and IAPs

Upon activation, tumor necrosis factor alpha （TNF-α） receptor can engage apoptotic or survival pathways. Inhibition of macromolecular synthesis is known to sensitize cells to TNF-α-induced cell death. It is believed that this sensitization is due to the transcriptional blockade of genes regulated by NF-κB. Nevertheless, such evidence has remained elusive in the nervous system. Here, we show that TNF-α cannot normally induce apoptosis in PC12 cells or cortical neurons. However, cells treated with Actinomycin D （ActD） become susceptible to TNF-α-induced cell death through the activation of caspase-8, generation of tBid and activation of caspase-9 and -3. Analysis of several proteins involved in TNF-α receptor signaling showed no significant downregulation of NF-κB target genes, such as IAPs or FLIP, under such conditions. However, Bcl-XL protein levels, but not those of Bcl-2, Bax and Bak, are reduced by ActD or TNF-α/ ActD treatments. Moreover, Bcl-xL overexpression fully protects cells against TNF-α/ActD-induced cell death. When endogenous levels of Bcl-XL are specifically downregulated by lentiviral-based RNAi, cells no longer require ActD to be sensitive to TNF-α-triggered apoptosis. Furthermore, Bcl-xL downregulation does not affect TNF-α-mediated NF-κB activation. Altogether, our results demonstrate that Bcl-XL, and not Bci-2, FLIP or IAPs, acts as the endogenous regulator of neuronal resistance/sensitivity to TNF-α-induced apoptosis in an NF-κB-independent manner.

Intracranial hemorrhage in patients treated with bevacizumab:Report of two cases

Treatment with bevacizumab,an antiangiogenic agent,in patients with metastatic or unresectable colorectal cancer was approved less than 4 years ago in Japan.Bevacizumab improves the survival of patients with metastatic colorectal cancer;however,it may lead to complications such as bleeding,which are sometimes fatal.Bevacizumab should be administered only after careful consideration because the potential risks of therapy outweigh its benefits.Therefore,pharma-ceutical companies do not recommend bevacizumab therapy for patients with brain metastases.While some reports support the cautious use of bevacizumab,others report that it is not always necessary to prohibit its use in patients with metastases to the central nervous system(CNS),including the brain.Thus,bevacizumab therapy in colorectal cancer patients with brain metastases is controversial,and it is unclear whether brainmetastases are a risk factor for intracranial hemor-rhage during anti-vascular endothelial growth factor(VEGF)therapy.We report a 64-year-old man and a 65-year-old man with recurrent colorectal cancer with-out brain metastases;these patients developed multifocal and solitary intracranial hemorrhage,respectively,after the administration of bevacizumab.Our findings suggest that intracranial hemorrhage can occur even if the patient does not have brain metastases prior to bevacizumab treatment and also suggest that brain metastases are not a risk factor for intracranial hemor-rhage with bevacizumab treatment.These findings also question the necessity of excluding patients with brain metastases from clinical trials on anti-VEGF therapy.

The Research on Key Technologies of Chinese Heavy-Lift Launch Vehicle Control System

This paper reviewed the development of control technology in domestic and foreign launch vehicle(LV), and based on which, the key technologies of control system for Chinese heavy-lift launch vehicles were proposed. A dynamic on-line trajectory planning technique was discussed to meet the demand of guidance control under complex constraints, and model based identification and adaptive control technology was suggested to deal with the control problems caused by model uncertainty and disturbance, and an integrated avionics system based on high speed communication was put forward for module integration and distributed control, and FBG based real time flight control was also discussed. Moreover, other key technologies, such as wireless interconnection, wireless power transfer, and temporal and spatial partitioning operating system, are both briefly introduced for the application in control systems. These studies will lead to breakthroughs in autonomous flight control in LV, and provide technical support for more long-term deep space explorations.

Observations on Spore Morphology of the Chinese Liverworts

The spore morphology of 9 species of 3 genera of Chinese liverworts was studied by scanning electron microscopic observation. They are Riccia huebeneriana Lindenb., R. hantamensis Perold., R. cavernosa Hoffm., R. warnstorfii Limpr. ex Warnst., R. frostii Aust., R. chinensis Herz., Asterella yoshinagana (Horik.) Horik., A. sanguinia L. et L., and Preissia quadrata (Scop.) Nees. There were evident morphological differences in spores among the above three genera. Difference of species morphology in the same genus was also observed. Therefore in the above genera and species the spore-wall ornamentation can be regarded as a criterion for taxonomic specificity. Meanwhile, slight difference in morphological characters of the same species collected from different sites was observed and reckoned to be an ecological adaptation.

Neutron Radiography System Collimator Design via Monte Carlo Calculation

Neutron radiography uses the unique interaction probabilities of neutrons to create images of materials. This imaging technique is non-destructive. MCNP Monte Carlo Code has been used to design an optimized neutron radiography system that utilizes 241Am-Be neutron source. Many different arrangements have been simulated to obtain a neutron flux with higher amplitude and more uniform distribution in the collimator outlet, next to image plane. In the final arrangement the specifications of neutron filter, Gamma-ray shield and beam collimator has been determined. Simulations has been carried out for a 5Ci 241Am-Be neutron source. In this case 43.8 n/cm2s thermal neutron flux has been achieved at a distance of 35 cm from neutron source.

The design and calculation of the delayed neutron detection system for PWR and CEFR

This paper discussed the importance of the delayed neutron detection system.We improved the delayed neutron detection station and delayed neutron detector,so the noise was greatly decreased and the detection efficiency was greatly increased.After the improvement the stability of the detector was enhanced and the false alarm was eliminated.We introduced the principle of the gas lift pump designed for the sodium cooled fast reactor.A calculation model of the failed fuel detection system of CEFR was proposed,and from the model a code using LabWindows/CVI was developed.The minimum broken area that could be detected by the delayed neutron detection system of CEFR was calculated and the delayed neutron detection signal in a few representative transient conditions during fuel failure happened was stimulated.

Joint Subcarrier and Power Allocation for DF-Based Multiuser Two-Way Relay Networks

Two-way decode-and-forward(DF) relay technique is an efficient method to improve system performance in 5G networks.However,traditional orthogonal frequency division multiplexing(OFDM) based two-way relay systems only consider a per-subcarrier relay strategy,which treats each subcarrier as a separate channel,which results in significant sum rate loss,especially in fading environments.In this paper,a joint coding scheme over multiple subcarriers is involved for multipair users in two-way relay systems to obtain multiuser diversity.A generalized subcarrier pairing strategy is proposed to permit each user-pair to occupy different subcarriers during the two transmission phases,i.e.,the multiple access and broadcast phases.Moreover,a low complexity joint resource allocation scheme is proposed to improve the spectrum efficiency with an additional multi-user diversity gain.Some numerical simulations are finally provided to verify the efficacy of our proposal.

Impact of the Target Film Thickness on the Properties of the Neutron Tube

Neutron tube is a kind of accelerator neutron source, which has been applied extensively. It is mainly composed of an ion source system, an accelerator system, and a target system. The target system is one of the most important parameters of the neutron tube and it impacts directly the yield, the lifetime, and the stability. By far the relation between the property of neutron tube and target thickness has not been studied drastically in the Institute of Radiation Technology of Northeast Normal University. High-quality titanium target should be produced in order to manufacture the neutron tube with intense yield, long lifetime and high stability. In our experiment, the pure titanium film was evaporated on the ceramic target by using the evaporation technique. The impact of the thickness of the titanium film on the yield of the neutron tube was studied, and the yield of the neutron tube was on optimistic state if the thickness of titanium film was 2.2 μm. The properties of training and stability of neutron tubes with different thick titanium film target were also present in this paper.

Unplanned Shutdown Frequency Prediction of FBR MONJU Using Fault Tree Analysis Method

In order to evaluate the operational reliability of Japanese FBR （fast breeder reactor） MONJU, frequencies of important intermediate events and equipment failures resulting during reactor automatic trip are predicted using FTA （fault tree analysis） technique for the plant system model. The targeted devices are the following： PHTS （primary heat transport system）, SHTS （secondary heat transport system）, WS （water and steam system）, PPS （plant protection system） and PCS （plant control system）. In this paper, the frequency of automatic reactor trips was estimated by extracting and analyzing the important intermediate events and equipment failures covering all the derived fault trees of these systems. The analyses predicted 1.2/RY （reactor year） the value of unplanned shut down frequency by the internal factor of the system. The largest contributed event was function failure of SHTS accounting for 42.6% of total events followed by PHTS with 40.1%. The contribution factor of WS was only 4.4%.

过套管脉冲中子密度测井的改进

利用标准脉冲中子系统测定地层密度的实践应用在参考文献1，文献2，文献3，文献4和文献5中都有描述。该系统已成功地应用于诸多储层的测井，这成功引出一个明显的问题；为这种测量而优化的系统可否进一步加以发展？为弄清何种参数应当测量，表征或要求改进其响应，要求建立一个更加确切的分析模型。脉冲中子密度测量是建立在快中子非弹性散射产生的伽马射线的传播基础上的。目前的密度算法利用的是伽马射线传播过程的扩散模型。这种简单的模型未包括快中子参数变化对产生伽马射线的影响。结果在和伽马源的动态性质相关的密度测井中引入不确定因素。伽马射线的初始分布是随着原子密度和氢含量而变化的，应恰当地将它视为建立一个更加确切的传播模型的第一步。利用理论模型。试验室地层和试井得出的响应以及通过计算机模拟。可实现对脉冲中子密度测量的分析和优选。为了合并快中子探测器和优选伽马射线探测器的距离。本文示出数据以及数据支持的经改进后的一个测量分析模型。作为此项研究的结果。文中叙述了一种可提高密度响应的标准探测器组合。

New concept for ADS spallation target: Gravity-driven dense granular flow target

For the Chinese-ADS project, to provide enough neutrons to drive the subcritical system, tens of MW spallation targets for the C-ADS are necessary. This is not an easy task. Here we propose a new concept for a gravity-driven dense granular flow target, in which heavy metal grains are chosen as the spallation target material. Compared with currently widely used targets, this conceptual design has advantages with regard to heat removal, thermal shock protection, neutron yield, radiotoxicity reduction, and convenient operation. The gravity-driven dense granular flow target has the potential to easily deal with these issues and to form a foundation for tens of MW spallation targets for cost-effective facilities. Preliminary simulations and experiments have been completed to support this conceptual design.

Application of Systems Biology Technology in Research of Traditional Chinese Medicine

Systems biology is an emerging science of the 21st century and its method and design of study resemble those of traditional Chinese medicine (TCM). Adopting systems biology technology will help to understand TCM Syndromes and modernize Chinese herbal medicine. The technology platforms of systems biology, especially proteomics can provide useful tools for exploring essence of TCM syndromes and understanding principle of herbal formulation. Moreover, compared with methods of molecular biology, such as genomics and proteomics, metabolomics provide more direct, rapid, concise and effective methods for study of kidney disease especially in the case of prevention and treatment with TCM.

Detector control system for Daya Bay Reactor Neutrino Experiment

The Daya Bay Reactor Neutrino Experiment is to measure the smallest mixing angle θ13.The experiment contains three major experiment halls,Daya Bay near site,Linao near site and far site,and two major kinds of detectors,antineutrino detector which is to detect the antineutrinos by the inverse beta-decay reaction in Gd-LS,and muon detector which is to study and reject cosmogenic backgrounds.The goal of the detector control system(DCS)is to operate and detect the detectors and keep them running in safety.In consideration of the limited fund of this system and manpower of working on this system,the LabVIEW is chosen to develop the detector control system.The architecture of DCS adopts the distributed data management which is based on client-server model.The server part is to detect and operate parameters from hardware,save data to database and release data to clients,the client is to receive data from the server.The detector control system contains three parts:the hardware part,the local control system and the global control part.The local control system includes high voltage supply system,low voltage supply system,VME crate system,temperature and humidity system,gas pressure system,and so on.