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体质量指数与中心动脉血流动力学指标的关系研究 被引量:2
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作者 晁慧娟 马瑾 +4 位作者 唐碧雯 胡月亮 王潜 宣言 左君丽 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2019年第12期1422-1426,共5页
目的·研究体检人群中体质量指数(body mass index,BMI)与中心动脉血流动力学指标之间的关系。方法·纳入2017年12月-2018年6月上海交通大学医学院附属瑞金医院北院体检中心体检者共计287例(男性164例,占57.1%);根据BMI将对象分... 目的·研究体检人群中体质量指数(body mass index,BMI)与中心动脉血流动力学指标之间的关系。方法·纳入2017年12月-2018年6月上海交通大学医学院附属瑞金医院北院体检中心体检者共计287例(男性164例,占57.1%);根据BMI将对象分为BMI正常组(BMI<24 kg/m^2)、超重组(24 kg/m^2≤BMI<28 kg/m^2)和肥胖组(BMI≥28 kg/m^2)。分别测定外周收缩压(peripheral systolic blood pressure,PSP)、外周舒张压(peripheral diastolic blood pressure,PDP)、外周脉压(peripheral pulse pressure,PPP)、外周平均动脉压(peripheral mean arterial pressure,P-MAP);采用脉搏波分析测定中心动脉压,包括中心动脉收缩压(central systolic blood pressure,CSP)、中心动脉舒张压(central diastolic blood pressure,CDP)、中心动脉脉压(central pulse pressure,CPP)、中心动脉增强压(central augmentation pressure,AP)、中心动脉反射波增强指数(central augmentation index,AIx);脉压放大指数为PPP/CPP。结果·①3组之间,PDP、CDP、P-MAP、AP、AIx、PPP/CPP差异有统计学意义(均P<0.05)。②Pearson相关性分析显示,BMI与AP、AIx呈负相关(r=-0.140,r=-0.149,均P<0.05),而与PDP、CDP、PPP/CPP呈正相关(r=0.151,r=0.155,r=0.124,均P<0.05)。③多元线性回归分析未发现BMI是CSP的独立相关因素。结论·随着BMI增加,AP、AIx呈下降趋势,PDP、CDP、PPP/CPP呈上升趋势;BMI与CSP间无明显相关性。 展开更多
关键词 体质量指数 中心动脉 中心动脉增强压 中心动脉反射波增强指数
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Modulation by anti-oketsu formulations in Kampo medicine of human arterial stiffness
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作者 Hiroyasu Satoh 《Traditional Medicine Research》 2017年第3期130-138,共9页
Objective:In traditional herbal medicine(Kampo medicine in Japan),'sho'is diagnosed by the traditional assessments of clinical conditions.Among a variety of the shos,there is an'oketsu'syndrome,which i... Objective:In traditional herbal medicine(Kampo medicine in Japan),'sho'is diagnosed by the traditional assessments of clinical conditions.Among a variety of the shos,there is an'oketsu'syndrome,which is a stagnation and disturbance of microcirculation.The prompt effects of four anti-oketsu formulations in Kampo medicine on cardiovascular functions were compared in oketsu and non-oketsu persons.Methods:The arterial pulse wave from radial artery is formed by the combination with ejection and reflection pulses.An augmentation index(AI),a ration of the ejection and reflection pulses,indicates a degree of arteriosclerosis.For both seventy-six students with oketsu and thirty-seven students with non-oketsu,Kampo formulations overcoming oketsu of Tokishakuyakusan(TS,Dang-Gui-Shao-Yao-San),Kamishoyosan(KS,Jia-Wei-Xiao-Yao-San),Keisibukuryogan(KB,Gui-Zhi-Fu-Ling-Wan)and Tokakujokito(TJ,Tao-He-Cheng-Qi-Tang)were taken once,and then,the cardiovascular functions including blood pressure,heart rate,central arterial blood pressure(CBP)and AI were examined for 60 min.Results:At 40-60 min after an intake,these formulations decreased the AI almost by 6-18%(n=76),by 18.3±3.1%(P<0.01,n=15)with TJ.Simultaneously,the CBP was reduced by 9.0±1.8%(P<0.05,n=23)with KS and by 9.1±2.0%(P<0.05,n=15)with TJ.On the other hands,non-oketsu group had less or no effect by any kinds of the formulations.Conclusion:The anti-oketsu formulations can exert the ameliorative action for oketsu persons via decreasing AI and CBP. 展开更多
关键词 Kampo medicine Sho Oketsu Disturbances of microcirculation Augmentation index Central arterial blood pressure
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