柯兴氏综合征的药物治疗

柯兴氏综合征又称皮质醇增多症,是以肥胖、多血质、下肢近端肌萎缩、无力、高血压、皮肤变薄、紫纹、痤疮、多毛、月经失调、骨质疏松和精神症状为突出表现;可伴有红血细胞和中性白细胞增多、嗜酸粒细胞和淋巴细胞戚少、糖耐鼠降低、代谢性碱中毒以及高尿钙症等。所谓医原性柯兴氏综合征系因长期摄取糖皮质激素治疗一些慢性病所致。

变态反应及中毒性皮肤病

0139038 中性白细胞增多性药疹/Rou-jeau J C//Clin Dermatol.-2000,18(3).-331～337 医科情0139039 肝素诱导的皮肤坏死/Khan Z//Br J Obstet Gynaecol.-2000,107(10).-1315～1316

原因未明的皮肤病

0139041 银屑病、扁平苔癣和角化病:未经批准的疗法或适应症/Capella C L//ClinDermatol.-2000,18(2).-159～169医科情0139042 持久性隆起性红斑/Gibson L E//Clin Dermatol.-2000,18(3).-295～299医科情0139043 Sweet 综合征:一种伴有典型急性发作和发热的中性白细胞增多性皮肤病/Cohen P R//Clin Dermatol.-2000,18(3).-265～282

蜂针治疗Sweet综合征1则

Sweet综合征是一种以急性发热、外周血白细胞计数升高及痛性红斑、斑块或结节为主要表现,以真皮浅层成熟的中性粒细胞弥漫性浸润为病理特征的一种复杂难治性疾病。目前多以糖皮质激素治疗,但效果各异且易复发。该文采用蜂针治疗Sweet综合征1例,取得较好的疗效。

Sonographic signs of neutropenic enterocolitis

AIM： To investigate the sonographic features at time of diagnosis and follow-up in patients with neutropenic enterocolitis. METHODS： The sonographic findings in 14 patients with neutropenic enterocolitis were described and evaluated regarding symptoms and clinical outcome. RESULTS： In all patients with neutropenic enterocolitis, the ileocoecal region was involved with wall thickening 〉10 mm. A transmural inflammatory pattern, hypervascularity of the thickened bowel wall and free abdominal fluid were the common findings. The sonographically revealed thickness of the bowel wall was associated with lethal outcome （P〈0.03）. In the 11 surviving patients, the improvement of clinical symptoms was accompanied by progressive reduction of intestinal wall thickness. CONCLUSION： High-end sonography of the bowel is a helpful tool for diagnosis, assessment of prognosis and follow-up of patients with neutropenic enterocolitis. The ultrasonographically revealed bowel thickness reflects the severity and the course of the disease, and seems to be predictive for the clinical outcome.