To solve the problem of inaccurate angle adjustment in the self-assembly process, a new homogenous hybrid modular self-reconfigurable robot-Xmobot is designed. Each module has four rotary joints and a self-turning mec...To solve the problem of inaccurate angle adjustment in the self-assembly process, a new homogenous hybrid modular self-reconfigurable robot-Xmobot is designed. Each module has four rotary joints and a self-turning mechanism. With the proposed self-turning mechanism, the angle adjusting accuracy of the module is increased to 2°, and the relative position adjusting efficiency of the module in the self-assembly process is also improved. The measured maximum moving distance of the proposed module in a gait cycle is 11.0 cm. Aiming at the multiple degree of freedom （MDOF） feature of the proposed module, a motion controller based on the central pattern generator （CPG） is proposed. The control of five joints of the module only requires two CPG oscillators. The CPG-based motion controller has three basic output modes, i. e. the oscillation, the rotation, and the fixed modes. The serpentine and the wheeled movements of the H-shaped robot are simulated, respectively. The results show that the average velocities of the two movements are 15. 2 and 20. 1 m/min, respectively. The proposed CPG-based motion controller is evaluated to be effective.展开更多
Many behavioral activities of the horseshoe crab Limulus are rhythmic, and most of these are produced in large part by central pattern generators within the CNS. The chain of opisthosomal （‘abdominal＇） ganglia con...Many behavioral activities of the horseshoe crab Limulus are rhythmic, and most of these are produced in large part by central pattern generators within the CNS. The chain of opisthosomal （‘abdominal＇） ganglia controls gill movements of ventilation and gill cleaning, and the prosomal ring of fused ganglia （brain and segmental ‘thoracic＇ ganglia） controls generation of feeding and locomotor movements of the legs. Both the opisthosomal CNS and the prosomal CNS can generate behaviorally ap- propriate patterns of motor output in isolation, without movements or sensory input. Preparations of the isolated opisthosomal CNS generate rhythmic output patterns of motor activity characterized as fictive ventilatory and gill cleaning rhythms. Moreover, CNS preparations also express longer-term patterns, such as intermittent ventilation or sequential bouts of ventilation and gill cleaning. Such longer-term patterns are commonly observed in intact animals. The isolated prosomal CNS does not spontaneously generate the activity patterns characteristic of walking, swimming, and feeding. However, perfusion of octopamine in the isolated prosomal CNS activates central pattern generators underlying rhythmic chewing movements, and injection of octopamine into in- tact Limulus promotes the chewing pattern of feeding, whether or not food is presented. Our understanding of the ability of neu-romodulators such as octopamine to elicit or alter central motor programs may help to clarify the central neural circuits of pattern generation that oroduce and coordinate these rhythmic behaviors展开更多
This paper described a nonlinear model predictive controller for regulating a molten carbonate fuel cell (MCFC). A detailed mechanism model of output voltage of a MCFC was presented at first. However, this model was t...This paper described a nonlinear model predictive controller for regulating a molten carbonate fuel cell (MCFC). A detailed mechanism model of output voltage of a MCFC was presented at first. However, this model was too complicated to be used in a control system. Consequently, an off line radial basis function (RBF) network was introduced to build a nonlinear predictive model. And then, the optimal control sequences were obtained by applying golden mean method. The models and controller have been realized in the MATLAB environment. Simulation results indicate the proposed algorithm exhibits satisfying control effect even when the current densities vary largely.展开更多
The limited regenerative capacity of several organs, such as central nervous system(CNS), heart and limb in mammals makes related major diseases quite difficult to recover. Therefore, dissection of the cellular and mo...The limited regenerative capacity of several organs, such as central nervous system(CNS), heart and limb in mammals makes related major diseases quite difficult to recover. Therefore, dissection of the cellular and molecular mechanisms underlying organ regeneration is of great scientific and clinical interests. Tremendous progression has already been made after extensive investigations using several model organisms for decades. Unfortunately, distance to the final achievement of the goal still remains. Recently, zebrafish became a popular model organism for the deep understanding of regeneration based on its powerful regenerative capacity, in particular the organs that are limitedly regenerated in mammals. Additionally, zebrafish are endowed with other advantages good for the study of organ regeneration. This review summarizes the recent progress in the study of zebrafish organ regeneration, in particular regeneration of fin, heart, CNS, and liver as the representatives. We also discuss reasons of the reduced regenerative capacity in higher vertebrate, the roles of inflammation during regeneration, and the difference between organogenesis and regeneration.展开更多
基金The National Natural Science Foundation of China(No.61375076)Research&Innovation Program for Graduate Student in Universities of Jiangsu Province(No.CXLX13-085)the Scientific Research Foundation of Graduate School of Southeast University(No.YBJJ1350)
文摘To solve the problem of inaccurate angle adjustment in the self-assembly process, a new homogenous hybrid modular self-reconfigurable robot-Xmobot is designed. Each module has four rotary joints and a self-turning mechanism. With the proposed self-turning mechanism, the angle adjusting accuracy of the module is increased to 2°, and the relative position adjusting efficiency of the module in the self-assembly process is also improved. The measured maximum moving distance of the proposed module in a gait cycle is 11.0 cm. Aiming at the multiple degree of freedom （MDOF） feature of the proposed module, a motion controller based on the central pattern generator （CPG） is proposed. The control of five joints of the module only requires two CPG oscillators. The CPG-based motion controller has three basic output modes, i. e. the oscillation, the rotation, and the fixed modes. The serpentine and the wheeled movements of the H-shaped robot are simulated, respectively. The results show that the average velocities of the two movements are 15. 2 and 20. 1 m/min, respectively. The proposed CPG-based motion controller is evaluated to be effective.
基金the U.S. Public Health Service for research grant funding for much of the work in my laboratory
文摘Many behavioral activities of the horseshoe crab Limulus are rhythmic, and most of these are produced in large part by central pattern generators within the CNS. The chain of opisthosomal （‘abdominal＇） ganglia controls gill movements of ventilation and gill cleaning, and the prosomal ring of fused ganglia （brain and segmental ‘thoracic＇ ganglia） controls generation of feeding and locomotor movements of the legs. Both the opisthosomal CNS and the prosomal CNS can generate behaviorally ap- propriate patterns of motor output in isolation, without movements or sensory input. Preparations of the isolated opisthosomal CNS generate rhythmic output patterns of motor activity characterized as fictive ventilatory and gill cleaning rhythms. Moreover, CNS preparations also express longer-term patterns, such as intermittent ventilation or sequential bouts of ventilation and gill cleaning. Such longer-term patterns are commonly observed in intact animals. The isolated prosomal CNS does not spontaneously generate the activity patterns characteristic of walking, swimming, and feeding. However, perfusion of octopamine in the isolated prosomal CNS activates central pattern generators underlying rhythmic chewing movements, and injection of octopamine into in- tact Limulus promotes the chewing pattern of feeding, whether or not food is presented. Our understanding of the ability of neu-romodulators such as octopamine to elicit or alter central motor programs may help to clarify the central neural circuits of pattern generation that oroduce and coordinate these rhythmic behaviors
基金The National High Technology Research and Development Program of China (863 Program) (No.2003AA517020)
文摘This paper described a nonlinear model predictive controller for regulating a molten carbonate fuel cell (MCFC). A detailed mechanism model of output voltage of a MCFC was presented at first. However, this model was too complicated to be used in a control system. Consequently, an off line radial basis function (RBF) network was introduced to build a nonlinear predictive model. And then, the optimal control sequences were obtained by applying golden mean method. The models and controller have been realized in the MATLAB environment. Simulation results indicate the proposed algorithm exhibits satisfying control effect even when the current densities vary largely.
文摘The limited regenerative capacity of several organs, such as central nervous system(CNS), heart and limb in mammals makes related major diseases quite difficult to recover. Therefore, dissection of the cellular and molecular mechanisms underlying organ regeneration is of great scientific and clinical interests. Tremendous progression has already been made after extensive investigations using several model organisms for decades. Unfortunately, distance to the final achievement of the goal still remains. Recently, zebrafish became a popular model organism for the deep understanding of regeneration based on its powerful regenerative capacity, in particular the organs that are limitedly regenerated in mammals. Additionally, zebrafish are endowed with other advantages good for the study of organ regeneration. This review summarizes the recent progress in the study of zebrafish organ regeneration, in particular regeneration of fin, heart, CNS, and liver as the representatives. We also discuss reasons of the reduced regenerative capacity in higher vertebrate, the roles of inflammation during regeneration, and the difference between organogenesis and regeneration.
