肠燥灵配合手术治疗血热肠燥型肛裂120例效果观察

目的:观察肠燥灵配合手术治疗血热肠燥型肛裂的临床疗效及安全性。方法 :将符合纳入标准的120例患者随机分为2组,肠燥灵干预组(60例)采用肠燥灵结合手术治疗,对照组(60例)采用单纯手术治疗,观察两组切口愈合时间及术后并发症及综合疗效。结果:两组总有效率比较差异无统计学意义(P>0.05),但肠燥灵干预组缩短了切口愈合时间,且术后并发症亦少于对照组(P<0.05)。结论:肠燥灵结合手术治疗血热肠燥型疗效较好,且具有术后恢复快、疼痛轻、并发症少等优点。

Herbal medicines for the management of irritable bowelsyndrome:A comprehensive review

Irritable bowel syndrome (IBS) is a functional gut disorder with high prevalence.Because of various factors involved in its pathophysiology and disappointing results from conventional IBS medications,the treatment of IBS is challenging and use of complementary and alternative medicines especially herbal therapies is increasing.In this paper,electronic databases including PubMed,Scopus,and Cochrane library were searched to obtain any in vitro,in vivo or human studies evaluating single or compound herbal preparations in the management of IBS.One in vitro,3 in vivo and 23 human studies were included and systematically reviewed.The majority of studies are about essential oil of Menta piperita as a single preparation and STW 5 as a compound preparation.Some evaluated herbs such as Curcuma xanthorriza and Fumaria officinalis did not demonstrate any benefits in IBS.However,it seems there are many other herbal preparations such as those proposed in traditional medicine of different countries that could be studied and investigated for their efficacy in management of IBS.

Evaluation of Antitumor,Immunomodulatory and Free Radical Scavenging Effects of A New Herbal Prescription Seaweed Complex Preparation

Seaweed Complex Preparation （SCP） is a clinical traditional Chinese medicine preparation which is composed of seven traditional Chinese herbs, and it has been used for treatment of lung cancer, liver cancer and digestive cancer. However, little infor- mation is available about the pharmacodynamic basis. The antitumor, immunomodulatory and free radical scavenging effects of SCP were evaluated in this study. Transplanted tumor in vivo method was used to determine the antitumor effect. The effects on spleno- cyte proliferation and phagocytosis of macrophages in tumor-bearing mice were measured by the MTT method and the phagocytizing cock red blood cell （CRBC） method respectively. The scavenging activities of SCP on DPPH and hydroxyl radicals in vitro were investigated. It was found that the medium-dose and high-dose of SCP could significantly inhibit the growth of transplanted hepatic tumor of murine hepatocarcinoma cell line H22, and promote proliferation of splenocytes and phagocytosis of macrophages. SCP possessed noticeable scavenging activities on DPPH and hydroxyl radicals. The antiturnor effects of SCP might be achieved by im- proving immune system and scavenging free radicals, which is in accordance with the viewpoint of traditional Chinese medicine in promoting the body resistance and eliminating pathogenic factors for cancer treatment.

奥沙拉嗪钠口服联合中药保留灌肠治疗溃疡性结肠炎的临床疗效

为探讨奥沙拉嗪钠口服联合中药保留灌肠治疗溃疡性结肠炎（UC）的临床疗效，本研究对比分析单纯口服奥沙拉嗪钠（A组，27例）、复方黄柏液保留灌肠（B组，29例）、奥沙拉嗪钠口服联合复方黄柏液保留灌肠（C组，30例）和奥沙拉嗪钠口服联合中药复合方保留灌肠（D组，112例）四种方法治疗UC的疗效。结果显示，四组总有效率分别为77．8％（21／27）、75．9％（22／29）、96．7％（29／30）和95．5％（107／112），复发率分别为25．9％（7／27）、41．4％（12／29）、3．3％（i／30）和5．4％（6／112）。经统计学分析，C、D组总有效率明显高于A、B组，复发率明显低于A、B组，P均d0．05；C组与D组之间、A组与B组之间总有效率及复发率差异均无统计学意义，P均〉0．05。结果表明，奥沙拉嗪钠口服联合复方黄柏液或中药复合方保留灌肠治疗UC均可获得满意疗效。