【目的】通过观察益气活血中药对妇科恶性肿瘤患者术后血浆D-二聚体(D-dimer)、血液流变学及凝血功能的影响,探讨益气活血法预防妇科恶性肿瘤术后下肢深静脉血栓形成的初步机理。【方法】前瞻性选取27例妇科恶性肿瘤术后患者,随机分为...【目的】通过观察益气活血中药对妇科恶性肿瘤患者术后血浆D-二聚体(D-dimer)、血液流变学及凝血功能的影响,探讨益气活血法预防妇科恶性肿瘤术后下肢深静脉血栓形成的初步机理。【方法】前瞻性选取27例妇科恶性肿瘤术后患者,随机分为对照组13例和治疗组14例,应用益气活血中药通脉饮后,检测血浆D-dimer、血液流变学和凝血功能的变化。【结果】术后2 d 2组D-dimer均较术前显著升高(P<0.01);全血粘度(高、中、低切)均较术前降低(P<0.01)。术后15 d应用通脉饮治疗后,治疗组D-dimer水平较对照组明显下降(P<0.01);而全血粘度较对照组无明显变化(P>0.05)。凝血功能方面,术后2 d 2组血小板计数均较术前减少(P<0.01);凝血酶原时间(PT)、活化的部分凝血活酶时间(APTT)均较术前明显延长(P<0.01),而血浆纤维蛋白原(FIB)水平均显著升高(P<0.01)。术后15 d应用通脉饮预防后,治疗组血小板计数较对照组明显增多(P<0.01),而PT、APTT、FIB较对照组均无明显变化(P>0.05)。【结论】益气活血中药通脉饮预防妇科恶性肿瘤术后下肢深静脉血栓形成安全有效,其作用机制可能与益气活血中药能抑制血小板聚集,增加血循环中血小板的数量,释放纤维蛋白溶酶原激活因子等因素有关;同时,中药对血液流变学及PT、APTT无影响,故不增加术后出血的危险。展开更多
In addition to higher risks of various obstetric and gynaecological illnesses among women with obesity or who are overweight, maternal adiposity threatens the lifetime health of their offspring. Diverse treatments are...In addition to higher risks of various obstetric and gynaecological illnesses among women with obesity or who are overweight, maternal adiposity threatens the lifetime health of their offspring. Diverse treatments are provided, including complementary and alternative medicine such as Chinese medical practices. Acupuncture, a traditional Chinese medicinal method, is increasingly being applied to this health problem. This literature review analyses 25 clinical studies, involving 2407 participants aged 13-65 in Africa, Asia, the Middle East and North America. This illustrates the use of acupuncture alone or with other approaches to control body weight, obesity-induced diseases, and gynaecological health. Although positive indicators are presented, this study offers recommendations for enhancing reliability and validity in further research. It therefore suggests the use of acupuncture in dealing with obesity due to its efficacy, and economic and safety benefits.展开更多
文摘【目的】通过观察益气活血中药对妇科恶性肿瘤患者术后血浆D-二聚体(D-dimer)、血液流变学及凝血功能的影响,探讨益气活血法预防妇科恶性肿瘤术后下肢深静脉血栓形成的初步机理。【方法】前瞻性选取27例妇科恶性肿瘤术后患者,随机分为对照组13例和治疗组14例,应用益气活血中药通脉饮后,检测血浆D-dimer、血液流变学和凝血功能的变化。【结果】术后2 d 2组D-dimer均较术前显著升高(P<0.01);全血粘度(高、中、低切)均较术前降低(P<0.01)。术后15 d应用通脉饮治疗后,治疗组D-dimer水平较对照组明显下降(P<0.01);而全血粘度较对照组无明显变化(P>0.05)。凝血功能方面,术后2 d 2组血小板计数均较术前减少(P<0.01);凝血酶原时间(PT)、活化的部分凝血活酶时间(APTT)均较术前明显延长(P<0.01),而血浆纤维蛋白原(FIB)水平均显著升高(P<0.01)。术后15 d应用通脉饮预防后,治疗组血小板计数较对照组明显增多(P<0.01),而PT、APTT、FIB较对照组均无明显变化(P>0.05)。【结论】益气活血中药通脉饮预防妇科恶性肿瘤术后下肢深静脉血栓形成安全有效,其作用机制可能与益气活血中药能抑制血小板聚集,增加血循环中血小板的数量,释放纤维蛋白溶酶原激活因子等因素有关;同时,中药对血液流变学及PT、APTT无影响,故不增加术后出血的危险。
文摘In addition to higher risks of various obstetric and gynaecological illnesses among women with obesity or who are overweight, maternal adiposity threatens the lifetime health of their offspring. Diverse treatments are provided, including complementary and alternative medicine such as Chinese medical practices. Acupuncture, a traditional Chinese medicinal method, is increasingly being applied to this health problem. This literature review analyses 25 clinical studies, involving 2407 participants aged 13-65 in Africa, Asia, the Middle East and North America. This illustrates the use of acupuncture alone or with other approaches to control body weight, obesity-induced diseases, and gynaecological health. Although positive indicators are presented, this study offers recommendations for enhancing reliability and validity in further research. It therefore suggests the use of acupuncture in dealing with obesity due to its efficacy, and economic and safety benefits.