中药茜草的研究进展

茜草科茜草属植物茜草(Rubiac cordi folia L.)具有重要的药用价值.该药用植物的研究近年来取得了广泛的进展,最新的研究发现茜草具有高效抑制人体表皮细胞异常增殖的作用,更是引起了人们广泛的关注.本文主要介绍了近年来从中药茜草中分离得到的新的醌类、环己肽类、烯萜类、多糖类等化合物以及该药物在抗银屑病、抗癌、抗氧化等方面的研究进展,为中药茜草进一步开展成分和药效研究提供参考.

中药参草通脉汤结合西药治疗气虚血瘀水停型慢性心力衰竭116例疗效分析

目的探究中药参草通脉汤结合西药治疗气虚血瘀水停型慢性心力衰竭的临床效果。方法选取2016年3月至2017年7月在我院进行慢性心力衰竭的232例患者,将其分为西药组及联合组,分别进行单纯西药治疗及中西医结合治疗,并比较其治疗效果。结果联合组患者心力衰竭疗效积分有效率显著高于西药组(P<0.05),且EDV、ESV、SV、EF改善情况也优于西药组(P<0.05)。比较中医症候积分及生活质量评分,联合组评分改善情况明显优于西药组(P<0.05)。结论采用中药参草通脉汤结合西药治疗气虚血瘀水停型慢性心力衰竭对改善患者症状,改善心力衰竭情况具有明显益处。

中药“草菟汤”治疗慢性前列腺炎45例临床观察

作者以“草菟汤”治疗慢性前列腺炎45例，临床辨证分湿热下注、瘀血内阻、脾气虚弱、肾虚不固、虚实夹杂五型。经一疗程（一个月）的治疗，痊愈27例，显效8例，有效6例，无效4例，总有效率为91．11％，与采用口服氟哌酸的32例对照组比较，中药“草菟汤”治疗慢性前列腺炎的疗效优于氟哌酸。

应用CTA评价鹤童草中药胶囊治疗冠状动脉狭窄的效果

目的探讨应用冠状动脉CT血管成像技术评价鹤童草中药胶囊治疗冠状动脉狭窄的效果。方法收集2018年6月至2020年7月符合纳入条件的门诊患者65例,口服鹤童草中药胶囊12个月,服药前后分别进行冠状动脉CT血管成像检查并对比分析。结果65例研究对象中,非钙化斑块48处,混合斑块98处,钙化斑块56处;斑块引起的冠状动脉狭窄共202处,其中轻度狭窄82处,占40.59%;中度狭窄73处,占36.14%;重度狭窄47处,占23.27%。65例患者202处冠状动脉狭窄:治愈84处,占41.59%(84/202);有效68处,占33.66%(68/202);无效50处,占24.75%(50/202)。结论鹤童草中药胶囊治疗冠状动脉狭窄性冠心病能使硬化斑块缩小或消失,狭窄、闭塞的血管再通,从而减缓动脉粥样硬化进程,改善症状,提高生活质量。

“医康养一体化”生态园景观规划设计

以生态宜居为目标,将医疗、健康和养生融为一体。遵循特色性、生态环保性、节约性的设计原则,结合许昌市建安区二郎庙社区独特的中草药资源,融入地域文化,设计“医康养一体化”生态园。根据区域资源禀赋,将园区规划成“一环、六区、十景”。按照医康养结合示范项目要求,将园区分为民俗风情区、花海观赏区、滨水游览区、模纹花坛区、中草药田区、休闲疗养区等,以期对城乡景观建设起到推动和示范作用。

石上柏与翠云草的比较鉴别

石上柏与翠云草为常用中草药,笔者在工作中发现两者常相互混淆。为了正确区别使用两者,本文对两者进行性状、组织和薄层层析比较鉴别。 石上柏、翠云草均由桂林药材站提供,经广西植物研究所韦发南教授鉴定为:(1)石上相为卷柏科植物深绿卷柏 Selaginella doeder-leinii Hieron的全草。(2)

海绵肾并发尿路感染的中药治疗和护理

目的探讨中药珍珠草及白花蛇舌草对海绵肾并发尿路感染的治疗效果。方法对临床7例海绵肾并尿路感染患者（其中6例曾因反复感染均用西药治疗过）实施珍珠草及白花蛇舌草的治疗，同时结合常规的饮食治疗和护理，1年后对7例患者进行随访以作中西药治疗效果的比较。结果不需西药治疗，珍珠草及白花蛇舌草可完全令患者尿路感染症状康复，同时促进海绵肾排出大量异物、砂石。结论珍珠草及白花蛇舌草治疗海绵肾并发尿路感染的效果显著。

Effect of Chinese Herbal Feed Additive on Meat Quality of Rex Rabbit

[ Objective] The aim of this study was to provide a theoretical basis for population and application of Chinese herbal feed additive in the rex rabbit breeding. [ Methyl] 108 weaned -rex rabbits aged 40 days were divided into three groups with thirty -six each group. Group A were fed basal diet, while group B were fed basal diet supplemented with 0.3% Chinese herbal feed additive and group C were fed basal diet supplemented with 0.4% Chinese herbal feed additive. The meat quality indexes were measured when feeding to 150 age in days. [ Result] There was significant difference among pH value, water loss rate, storing loss rate and crude protein content in each group （P〈0.05）, but no significant difference was found in tenderness, cooking percentage, moisture content and crude fat content （ P 〉 0.05）. The total content of ami- no acids, essential amino acids and semi essential amino acids as well as main delicious amino acids was highest in group C accounting for 23.84%, 11.47% and 8.32% respectively, next came group B accounting for 20.94%, 10.64% and 6.81% respectively, and lowest in group C （ control group） accounting for 19.06%, 9.61% and 6.46% respectively. [ Conclusion] The Chinese herbal feed additive can improve meat quality of rex rabbit the best addition of 0.4%.

Effects of Salinity and Dietary Chinese Herbal Medicine on Survival and Growth of Juvenile Fenneropenaeus chinensis

[Objective] The aim of this study was to provide theoretical basis for the large-scale breeding of Fenneropenaeus chinensis as well as the promotion of Chinese herbal medicine.[Method] The experiment was conducted to determine the effects of salinity（12‰,20‰ and 28‰）and dietary Chinese herbal medicine（CHM：0%,1%,2% and 4%）on survival and growth of juvenile F.chinensis with the average initial wet body weight of 0.027±0.005 g.The experiment lasted for 5 weeks.[Result] The survival rate,specific growth rate,food consumption and apparent digestibility coefficient was increased with CHM level increasing;when attained the critical value,the survival rate,specific growth rate,food consumption and apparent digestibility coefficient decreased with CHM level increasing.Food conversion ratio decreased with CHM level increasing,and then it increased after attained the critical value.At each CHM level,the survival rate,specific growth rate,food consumption and apparent digestibility coefficient were highest at salinity of 20‰,while food conversion ratio was lowest at salinity 20‰.[Conclusion] Salinity and CHM had a significant effect on growth of F.chinensis,which should be paid more attention in the breeding.

Research on Anti-bacterial Effects of 5 Kinds of Chinese Herb Extracts on Ameromonas hydrophila in vitro

[Objective] The aim was to study the anti-bacterial effects of 5 kinds of Chinese herb extracts on Ameromonas hydrophila in vitro. [Method] in vitro anti-bacterial effects of 5 kinds of Chinese herb extracts like Galla Chinensis,Syzygium aromaticum,Salvia miltiorrhiza,Punica granatum L. and Terminalia chebula Retz on Ameromonas hydrophila were studied; furthermore,cure rates of the Chinese herb extracts with better anti-bacterial effects were determined to find out the optimal drug dosage. [Result] Under the same experimental conditions,Galla Chinensis,Punica granatum and Terminalia chebula Retz had relatively strong anti-bacterial effects on Ameromonas hydrophila,among them the anti-bacterial effect of Galla Chinensis was significantly higher than those of the others （P0.05）. The optimal treatment dose of Galla Chinensis treating bacterial septicemia caused by Aeromonas hydrophila was that they were treated with medicated bath for 40 min by 0.5 mg/ml Galla Chinensis extract,and the cure rate was 100%. [Conclusion] The research provides a scientific drug basis for the control and prevention of outbreak bacterial diseases of fish.

Effects of a Self-made Compound Chinese Herbal Medicine Additive on Growth Performance and Occurrence of Diarrhea in Weaned Piglets

In this study,the effects of compound Chinese herbal medicine on growth performance and occurrence of diarrhea in weaned piglets were investigated.A compound Chinese herbal medicine that consisted of Astragalus membranaceus,Codonopsis pilosula,Epimedium sagittatum,massa medicata fermentata,Atractylodes macrocephala,malt,Glycyrrhiza uralensis,Angelica sinensis and Crataegus pinnatifida,was crushed and then passed through a 500-mesh sieve.The obtained powder was added to the basal diet of weaned piglets.A total of 100 healthy crossbred weaned piglets,aging 26±2 days,were selected.They were randomly divided into 5groups（20 piglets/group） in according to principles of similar parity（3-5）,similar body weight and half male and half female.The piglets in the control group were fed with basal diet.For the piglets in the I,II and III groups,0.4%,0.7% and 1.0%of Chinese herbal medicine additive were added to the basal diets,respectively.The basal diet of piglets in the IV group was added with 30 mg/kg of oxytetracycline.The results showed the incidences of diarrhea in I,II and III groups were4.85%,5.14% and 5.63% lower than that of control groups（P〈0.05）.There was no significant difference in incidence of diarrhea between the control and the IV groups.

Effects of Traditional Chinese Medicine on Numbers of Lymphocytes and Goblet Cells in Villus Epithelia of Layers under Heat Stress

[Objective] This study aimed to investigate the effects of traditional Chinese medicine additives on numbers of lymphocytes and goblet cells in villus epithelia of layers under heat stress.[Method] A total of 180 88-d-old healthy Esa Brown cocks were selected.They were randomly divided into 9 experimental groups：Room temperature control,High temperature control,VC addition group,High formula I,Moderate formula I,Low formula I,High formula II,Moderate formula II and Low formula II.The formula I and formula II were to add different herbal extracts to the diet of cocks with different doses.The cocks in the VC addition group were administered orally with same-concentration VC solution.After certain time,the cocks were slaughtered.Then the numbers of epithelial lymphocytes and goblet cells in various segments of small intestine were counted by using conventional histological section and HE staining.[Result] The numbers of lymphocytes and goblet cells in villus epithelia of layers under heat stress were decreased gradually with the proceeding of experiment.The herbal extracts of formula I and formula II all could promote the generation of lymphocytes and goblet cells.But the promoting effect of formula II was best.[Conclusion] The Chinese herbal medicine additives have a good relieving effect on heat stress in layers.

Isolation and Identification of the Pathogen Causing Skin Ulcer Disease in Cynoglossus semilaevis Günther and Its Sensitivity to Chinese Herbal Medicine

In this study, the pathogen causing skin ulcer disease in Cynoglossus semilaevis Gunther was isolated for morphological observation, physiological and bio- chemical identification. According to the result, the isolated pathogen was identified as Vibrio harveyi. The results of recurrent infection of C. semilaevis Gonther showed that the pathogen was strongly pathogenic to C. semilaevis Gunther. In or- der to explore the pathogenesis, outer membrane protein （OMP） gene of C. semi- laevis Gunther was detected by PCR. The results showed that all the three repre- sentative strains harbored OMP gene. According to the results of sensitivity test of the pathogen to Chinese herbal medicine, Galla Chinensis, Fructus Mume, Fructus Hippophae and Lignum Sappan exerted strong antibacterial effects against V. harveyr, Pericarpium Granati exhibited slight antibacterial effect against V. harveyi; Pericarpium Citri Reticulatae, Rhizoma Acori GramineL Herba Houttuyniae, Herba Portulacae, Herba Andrographis, Eucalyptus globulus Labill. and Herba Menthae Heplocalycis had little effect on V. harveyi. Galla Chinensis, Fructus Mume, Fructus Hippophae and Lignum Sappan were prepared into three prescriptions, among which prescription 1 （Galla Chinensis ＋ Fructus Mume） exhibited the strongest antibacterial effect.

Baiting Effects of 17 Chinese Medicinal Plants on Brachydanio rerio

The study aimed to discuss baiting effects of 17 kinds of Chinese medicinal plants on Brachydanio rerio.With 100 fish of Brachydanio rerio as tested objects,the average length of the 100 fish was 3.5 cm.Cinnamomum cassia,Mentha canadensis,Eugenia aromaticum,Coptis chinensis,Phellodendron amurense,Scutellaria baicalensis,star anise,Kaempferia galanga,Prunus mume,Magnolia sinensis,Terminalia chebula meat,Sophora flavescens,Polygonum cuspidatum,Rhizoma polygonatum,Astragalus membranaceus,Forsythia suspense and...

Wavy Distribution of Trace Elements in Phytolacca Samples from Different Areas

To study the distribution of 25 elements, i.e. Be, Cd, Ce, Cr, Cu, Dy, Er,Eu, Gd, Ge, Ho, La, Lu, Mo, Nd, Pb, Pr, Sm, Sr, Tb, Tl, Tm, Y, Yb and Zn in Phytolacca, atraditional Chinese medicinal herb, collected from nine areas of P. R. China. Methods Twenty-fiveelements in Phytolacca including essential elements, toxic elements and rare earth elements intraditional Chinese medicinal herbs from different areas were analyzed by ICP-MS. Results The 25elements in Phytolacca were determined by ICP-MS under optimized conditions. The detection limitswere 0.003 -0.71 ng·mL^(-1). The recoveries were 88% - 118% . The relative standard deviations ofthe measurements were 1.7% - 13.3%. Conclusion The determined concentrations of elements inPhytolacca acinosa Roxb vary from one area to another; however, the distribution tendency ofelements in all the samples is similar. The distribution tendency of rare earth elements inPhytolacca acinosa Roxb is consistent with that in nature.

Effects of Herbal Feed Additive on Milk Production of Dairy Cows

[Objective] The aim of this study was to investigate the efficacy of the herbal feed additive Zengrujianniusan on the milk production of dairy cows. [Method] Thirty-two black-white lactating cows were randomly divided into four groups, and were fed with forage supplemented with 0 （control group）, 0.2%, 0.4% and 0.6% Zengrujianniusan for 60 d. During this period, the contents of fat, protein and non-fat solid in milk were measured every 20 d. [Result] The milk production of the cows whose forage was added with 0.2 %, 0.4 % and 0.6% Zengrujianniusan was 4.02%, 12.50%, 14.00% higher than that of the control （P〉0.05）. The herbal feed additive had no significant influence on the contents of fat, milk and non-fat solid in milk, but significantly reduced the number of somatic cells. [Conclusion] The study will provide reference for developing feed additives which is safe and non-toxic to cows and their milk.

Investigation of Heavy Metal Contents in Traditional Chinese Herbal Medicine Peristrophe roxburghiana Collected from Northwest of Guangxi

Objective] This study was conducted to evaluate the product quality and safety of Peristrophe roxburghiana_ col ected from different places in Hechi City, northwest of Gunagxi, so as to provide basic data for further development and uti-lization of the characteristic plant resource P. roxburghiana. [Method] Contents of 9 kinds of heavy metals including Cd, Mn, Pb, Zn and Cu in the herb were deter-mined by the method of wet digestion-flame atomic absorption spectrophotometry and atomic fluorescence spectrometry, respectively. [Results] Heavy metal contents of Cd, Mn, Pb, Fe, Cu, Zn, As, Hg and Se were 1.62-17.25, 8.93-142.53, 4.37-18.43, 103.7-242.81, 2.55-5.35, 85.40-146.30, 0.07-0.54, 0.00-0.08 and 0.00-0.47 mg/kg, respectively. According to the national food safety standards and Green Trade Standards of lmporting ＆amp; Exporting Medicinal plants ＆amp; Preparations, the heavy metal contents of the P. roxburghiana_samples col ected from different coun-ties in Hechi City exceeded standards or at the critical values. Among which, Cd, Pb and Zn contents of the samples are seriously higher than the standards. [Con-clusion] Therefore, the impact of soil heavy metal pol ution on the safety of edible plants in the northwest of Guangxi should be highly concerned.

Triterpenoids from Rubus buergeri

A new triterpenoid, methyl buergericate (12a), which was elucidated as 2 alpha, 3 alpha, 19 alpha, 24-tetrahydroxyl olean-12-en-28-oic acid methyl ester by spectroscopic methods, together with eleven known triterpenoids was isolated from Rubus buergeri Miq. The isolation of the above chemical constituents from this plant was reported for the first time.

Effects of Salinity Fluctuation and Dietary Traditional Chinese Herbal Medicines on Survival,Growth and Immunity of Exopalaemon carinicauda

[Objective]The aim of this study was to provide a theoretical basis for the large-scale breeding of Exopalaemon carinicauda. [Method]Effects of salinity fluctuation （S0,S3,S6 and S9 represented salinity fluctuations of 0,3,6 and 9 respectivley） and dietary traditional Chinese herbal medicines （0,1%,2% and 4% respectively） on survival,growth and immunity of E.carinicauda were studied,and its experiment lasted for 60 d. [Result]The results showed that specific growth rate,feed conversion efficiency and superoxide dismutase activity of E.carinicauda in the treatment group with 1% dietary traditional Chinese herbal medicine and S6 salinity fluctuation were higher than those in other treatments,which was significantly higher than the treatment groups with S0,S3 and S9 salinity fluctuation at the same adding level of 1% dietary traditional Chinese herbal medicine. The regression analysis indicated that at S0,S3 and S6 salinity fluctuation,the optimal adding level of dietary traditional Chinese herbal medicines in feeds decreased with the increase of salinity fluctuation,accounting for 2.74%,1.77% and 0.51% respectively. At four adding levels of dietary traditional Chinese herbal medicines,the optimal salinity fluctuation of E.carinicauda also decreased with the increase of dietary traditional Chinese herbal medicines in feeds,accounting for 5.26,4.95,3.54 and 1.97 respectively. [Conclusion]Salinity,dietary traditional Chinese herbal medicines and their interactions have a significant effect on survival,growth and immunity of E.carinicauda,which calls for attentions in the breeding.

Chinese Herbal Medicine Resources with Bacteriostatic and Insecticidal Activities and Their Application as Pesticides

Herbal pesticides refer to the active ingredients extracted from herbs which are used for pest and disease control in crops or pure substances isolated from them. They are of great significance for the production of pollution-free agricultural products, as well as for exploiting the abundant plant resources in China for the prevention and control of pests. In this paper, the advantages of herbal pesticides,such as being environment-friendly, diverse patterns of action, safety for higher animals and the natural enemies of pests and making it hard for pests to produce resistance were first stated; then, Chinese herbal medicine resources with antibacterial and insecticidal activities from 49 families and their functions were reviewed, and 19kinds of herbal pesticides that have been developed and applied in China and seven kinds that have been produced on a large scale were also introduced; finally,three issues deserving further exploration during the development and application of herbal pesticides were presented, that is, research in variety selection and cultivation of herbs, and methods for extraction of active ingredients; basic research in the structure identification of herbal active ingredients, and the relationship between plant variety and active ingredients; development of lead compounds based on herbal active ingredients.