据医学空间网12月29日报道（原载Journal of Infections Diseases192（11）：1943-1949），肝脏皮脂腺病是丙型肝炎病毒感染患者中常见的症状，常常伴随着严重的肝纤维化。同时感染了HIV和丙型肝炎病毒的肝脏皮脂腺病人的特点目前还没...据医学空间网12月29日报道（原载Journal of Infections Diseases192（11）：1943-1949），肝脏皮脂腺病是丙型肝炎病毒感染患者中常见的症状，常常伴随着严重的肝纤维化。同时感染了HIV和丙型肝炎病毒的肝脏皮脂腺病人的特点目前还没有系统地研究过。科学家们检查了106名同时患有HIV和HCV但没有感染HBV的患者的肝脏活组织，检测皮脂腺病和脂肪性肝炎与病毒感染之间的关系，并由此来解释皮脂腺病的风险因子。展开更多
To evaluate the clinical characteristics, risk factors, and outcomes of hypotension in unselected patients who had acute aortic dissection(AAD), we studied 1,073 such patients who were enrolled in the International Re...To evaluate the clinical characteristics, risk factors, and outcomes of hypotension in unselected patients who had acute aortic dissection(AAD), we studied 1,073 such patients who were enrolled in the International Registry of Acute Aortic Dissection between 1996 and 2001. Hypotension was noted in 313 patients(29.2%)who had AAD(46.0%on admission). Multivariate logistic regression identified age ≥70 years(odds ratio [OR] 2.0, 95%confidence interval [CI] 1.4 to 2.9), type A dissection(referent type B AAD; OR 2.1, 95%CI 1.4 to 3.2), neurologic deficit(OR 3.8,95%CI 2.2 to 6.6), syncope(OR 2.9, 95%CI 1.8 to 4.7), aortic regurgitation requiring valve surgery(OR 1.9, 95%CI 1.1 to 3.3), cardiac tamponade(OR 5.1, 95%CI 3.0 to 8.8), and new Q-wave or ST-segment deviation on an electrocardiogram(OR 1.6, 95%CI 1.1 to 2.4)as independent associations of hypotension(c statistic 0.78). Hospital complications(neurologic deficits 22.7%vs 12.0%, altered mental status 26.1%vs 4.4%, myocardial ischemia 14.6%vs 6.9%, mesenteric ischemia 6.9%vs 2.6%, or limb ischemia 14.6%vs 6.9%, and death 55.0%vs 10.3%)occurred more frequently in patients who had hypotension than in those who did not(p< 0.001 for all comparisons). We concluded that hypotension that occurred in>25%of patients who had AAD was associated with a much higher rate of in-hospital adverse events. Our study also identified factors associated with hypotension in patients who had AAD.展开更多
文摘据医学空间网12月29日报道（原载Journal of Infections Diseases192（11）：1943-1949），肝脏皮脂腺病是丙型肝炎病毒感染患者中常见的症状，常常伴随着严重的肝纤维化。同时感染了HIV和丙型肝炎病毒的肝脏皮脂腺病人的特点目前还没有系统地研究过。科学家们检查了106名同时患有HIV和HCV但没有感染HBV的患者的肝脏活组织，检测皮脂腺病和脂肪性肝炎与病毒感染之间的关系，并由此来解释皮脂腺病的风险因子。
文摘To evaluate the clinical characteristics, risk factors, and outcomes of hypotension in unselected patients who had acute aortic dissection(AAD), we studied 1,073 such patients who were enrolled in the International Registry of Acute Aortic Dissection between 1996 and 2001. Hypotension was noted in 313 patients(29.2%)who had AAD(46.0%on admission). Multivariate logistic regression identified age ≥70 years(odds ratio [OR] 2.0, 95%confidence interval [CI] 1.4 to 2.9), type A dissection(referent type B AAD; OR 2.1, 95%CI 1.4 to 3.2), neurologic deficit(OR 3.8,95%CI 2.2 to 6.6), syncope(OR 2.9, 95%CI 1.8 to 4.7), aortic regurgitation requiring valve surgery(OR 1.9, 95%CI 1.1 to 3.3), cardiac tamponade(OR 5.1, 95%CI 3.0 to 8.8), and new Q-wave or ST-segment deviation on an electrocardiogram(OR 1.6, 95%CI 1.1 to 2.4)as independent associations of hypotension(c statistic 0.78). Hospital complications(neurologic deficits 22.7%vs 12.0%, altered mental status 26.1%vs 4.4%, myocardial ischemia 14.6%vs 6.9%, mesenteric ischemia 6.9%vs 2.6%, or limb ischemia 14.6%vs 6.9%, and death 55.0%vs 10.3%)occurred more frequently in patients who had hypotension than in those who did not(p< 0.001 for all comparisons). We concluded that hypotension that occurred in>25%of patients who had AAD was associated with a much higher rate of in-hospital adverse events. Our study also identified factors associated with hypotension in patients who had AAD.
