目的:探讨超声评分法在胎盘植入性疾病(placenta accr eta spectr um,PAS)严重程度预测中的应用价值。方法:收集2020年1月1日至2022年6月30日彭水苗族土家族自治县中医院妇产科收治的100例疑似PAS的孕产妇作为研究对象。对其均进行超声...目的:探讨超声评分法在胎盘植入性疾病(placenta accr eta spectr um,PAS)严重程度预测中的应用价值。方法:收集2020年1月1日至2022年6月30日彭水苗族土家族自治县中医院妇产科收治的100例疑似PAS的孕产妇作为研究对象。对其均进行超声检查,对比超声评分法与“金标准”(手术探查)在诊断PAS、初步诊断PAS严重程度、诊断不同严重程度PAS上的差异,从多个角度评估术前超声评分法诊断PAS的临床价值。结果:在诊断孕产妇是否存在PAS上,术前超声评分法与“金标准”之间无明显差异(P=0.687);在初步诊断孕产妇不同严重程度PAS(粘连、植入和穿透)上,术前超声评分法与“金标准”的一致性良好(Kappa值为0.880,P<0.001);术前超声评分法对诊断不同严重程度PAS的准确性不同,对PAS-2、PAS-3、PAS-6的诊断具有高准确性,对PAS-4、PAS-5的诊断具有较高的准确性,对PAS-6的诊断准确性最高(AUC=0.881)。总体上,超声评分法诊断PAS具有高准确性(P<0.05)。结论:超声评分法对PAS的严重程度具有良好的临床预测价值,但在诊断不同严重程度PAS方面存在一定的差异。展开更多
Aims: To ascertain whether the severity of childhood asthma can be reliably assessed by simple clinical features, 94 newly diagnosed, school-aged asthmatic children were investigated. Methods: The study included paren...Aims: To ascertain whether the severity of childhood asthma can be reliably assessed by simple clinical features, 94 newly diagnosed, school-aged asthmatic children were investigated. Methods: The study included parental interviews, physical examination, skin prick tests, lung function studies, including a brief visual interpretation of the flow-volume curve, and a 6-min exercise challenge test on a treadmill, which was used as a reference. Results: Baseline lung function studies showed a concave-shaped flow-volume curve in 40 (43% ) patients, reduced maximal mid-expiratory flow (MMEF) in 25 (27% ) and a reduced ratio of forced expiratory volumein 1 s to forced vital capacity (FEV1/FVC) in 14 (15% ). The drop in peak expiratory flow (PEF) after exercise ranged from 0 to 79% of the baseline (mean 21.3% ) and exceeded 12.5% in 52 (55% ) patients. There was a small but significant correlation between the baseline FEV1/FVC and MMEF values and the response to exercise (r=-0.39 and -0.35; p=0.001, respectively), but when studied by linear regression analysis, the response to exercise was best predicted by the past symptom rate and a concave pattern in the pre-test maximal expiratory flow-volume curve. The values of traditional lung function tests or age, atopy, duration of symptoms or history of exercise-induced wheezing did not remain in the model. Conclusions: These results show that the severity of asthma in school-aged children can be predicted at the first visit based on the past rate of symptoms and a visual interpretation of the maximal expiratory flow-volume curve.展开更多
背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低。目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系。方法选取上海市精神卫生中心的51例住院男性精神分...背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低。目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系。方法选取上海市精神卫生中心的51例住院男性精神分裂症患者,其中40例患者最终完成了个体和社会功能量表(Personal and Social Performance Scale,PSP)中文版、临床疗效总评量表-病情严重程度量表(Clinical Global Impression-Severity,CGI-S)、阳性和阴性症状量表(Positive and Negative Symptom Scale,PANSS)、字母-数字排序以及香港文字记忆学习测试等项目的评定。结果患者PANSS量表的3个临床分量表的分值和社会功能总体评估(PSP总分和CGI-S分值)之间存在明显负相关。患者的神经认知测定结果与症状或社会功能状况均无关。结论对于急性期住院精神分裂症患者而言,临床症状的严重度—而非神经认知缺损程度,与其社会功能水平密切相关。展开更多
文摘目的:探讨超声评分法在胎盘植入性疾病(placenta accr eta spectr um,PAS)严重程度预测中的应用价值。方法:收集2020年1月1日至2022年6月30日彭水苗族土家族自治县中医院妇产科收治的100例疑似PAS的孕产妇作为研究对象。对其均进行超声检查,对比超声评分法与“金标准”(手术探查)在诊断PAS、初步诊断PAS严重程度、诊断不同严重程度PAS上的差异,从多个角度评估术前超声评分法诊断PAS的临床价值。结果:在诊断孕产妇是否存在PAS上,术前超声评分法与“金标准”之间无明显差异(P=0.687);在初步诊断孕产妇不同严重程度PAS(粘连、植入和穿透)上,术前超声评分法与“金标准”的一致性良好(Kappa值为0.880,P<0.001);术前超声评分法对诊断不同严重程度PAS的准确性不同,对PAS-2、PAS-3、PAS-6的诊断具有高准确性,对PAS-4、PAS-5的诊断具有较高的准确性,对PAS-6的诊断准确性最高(AUC=0.881)。总体上,超声评分法诊断PAS具有高准确性(P<0.05)。结论:超声评分法对PAS的严重程度具有良好的临床预测价值,但在诊断不同严重程度PAS方面存在一定的差异。
文摘Aims: To ascertain whether the severity of childhood asthma can be reliably assessed by simple clinical features, 94 newly diagnosed, school-aged asthmatic children were investigated. Methods: The study included parental interviews, physical examination, skin prick tests, lung function studies, including a brief visual interpretation of the flow-volume curve, and a 6-min exercise challenge test on a treadmill, which was used as a reference. Results: Baseline lung function studies showed a concave-shaped flow-volume curve in 40 (43% ) patients, reduced maximal mid-expiratory flow (MMEF) in 25 (27% ) and a reduced ratio of forced expiratory volumein 1 s to forced vital capacity (FEV1/FVC) in 14 (15% ). The drop in peak expiratory flow (PEF) after exercise ranged from 0 to 79% of the baseline (mean 21.3% ) and exceeded 12.5% in 52 (55% ) patients. There was a small but significant correlation between the baseline FEV1/FVC and MMEF values and the response to exercise (r=-0.39 and -0.35; p=0.001, respectively), but when studied by linear regression analysis, the response to exercise was best predicted by the past symptom rate and a concave pattern in the pre-test maximal expiratory flow-volume curve. The values of traditional lung function tests or age, atopy, duration of symptoms or history of exercise-induced wheezing did not remain in the model. Conclusions: These results show that the severity of asthma in school-aged children can be predicted at the first visit based on the past rate of symptoms and a visual interpretation of the maximal expiratory flow-volume curve.
基金supported by funds awarded to Dr.Linda Byrne from the Adult Mental Health Strategic Research Centrethe School of Psychology at Deakin University,Melbourne,AustraliaDr.Daihui Peng from the Shanghai City Health Bureau Fund(grant number:2010086)
文摘背景以往研究表明精神分裂症患者的神经认知缺损和精神病性症状会导致其职业和社会功能降低。目的评估中国精神分裂症男性住院患者的神经认知和精神病性症状与社会心理功能之间的关系。方法选取上海市精神卫生中心的51例住院男性精神分裂症患者,其中40例患者最终完成了个体和社会功能量表(Personal and Social Performance Scale,PSP)中文版、临床疗效总评量表-病情严重程度量表(Clinical Global Impression-Severity,CGI-S)、阳性和阴性症状量表(Positive and Negative Symptom Scale,PANSS)、字母-数字排序以及香港文字记忆学习测试等项目的评定。结果患者PANSS量表的3个临床分量表的分值和社会功能总体评估(PSP总分和CGI-S分值)之间存在明显负相关。患者的神经认知测定结果与症状或社会功能状况均无关。结论对于急性期住院精神分裂症患者而言,临床症状的严重度—而非神经认知缺损程度,与其社会功能水平密切相关。
