微波辐射下合成5-亚苄基假乙内酰硫脲

在微波辐射条件下,以冰醋酸为介质,醋酸钠为催化剂,使芳醛与假乙内酰硫脲发生缩合反应,生成5-亚苄基假乙内酰硫脲,该法在10 min内完成,产率63%～91%,具有反应时间短、操作简便和环境友好等优点.

新型2-乙内酰硫脲衍生物的合成与表征

通过异氰酸酯法合成一系列新型2-乙内酰硫脲衍生物,应用1H NMR、13C NMR、IR测试技术对分子的结构进行了表征;初步测定了化合物的除草活性;对构效关系进行了分析。结果表明,在乙内酰硫脲5位上含有甲基取代基的化合物的除草活性要高于5位上没有取代基的化合物。最大的芽抑制率为56.5%,最大的根抑制率为53.8%。2-乙内酰硫脲衍生物可以作为一类新的农药先导化合物。

对苯基双乙内酰硫脲衍生物的合成与表征

以对苯二甲醛为原料,制得对苯基双异硫氰酸酯,再和L构型的氨基酸反应制得11种含有双杂环基团的对苯基双乙内酰硫脲类衍生物,其中有9种未见文献报道。产物经1HNMR、13CNMR和元素分析得到了确认和表征。

一种用于蛋白质C端序列测定的脯氨酸乙内酰硫脲(TH-Pro)新制备方法

采用Ｌ－型脯氨酸（Ｌ－Ｐｒｏ）作为原料，三甲基硅烷异硫氰酸酯（ＴＭＳ－ＩＴＣ）作为偶联试剂制备脯氨酸乙内酰硫脲（ＴＨ－Ｐｒｏ）．产物经反相ＨＰＬＣ分离纯化，并通过氨基酸组成分析，紫外光谱扫描，质谱和核磁共振等方法鉴定．反应产率高达９６％．

Depression effect of pseudo glycolythiourea acid in flotation separation of copper-molybdenum

Pseudo glycolythiourea acid（PGA） was synthesized and used as depressant for flotation separation of Cu and Mo.The results indicate that a low amount of PGA has strong depression effect on chalcopyrite.Mo grade of 26.17% and recovery of 89.83% were achieved with rougher and scavenger one time and cleaners twice,while the recovery of Mo was deceased by 2% when Na2S was used as depressant.Measurement on adsorption of PGA on the mineral surface indicates that PGA and xanthate were adsorbed on mineral surface by competition,and PGA was adsorbed on chalcopyrite surface much stronger than on molybdenite surface.FTIR results indicate a chemical absorption process for PGA on chalcopyrite surface and a physical adsorption process on molybdenite surface.The frontier orbital calculation shows that the S atom is an active center,and the depression of PGA can be explained with the Fermi level of energy based on the electrochemical mechanism.

Efficient synthesis of thiohydantoin derivatives from amino acid esters and isothiocyanates in alkaline Al_2O_3

Various amino acid esters were reacted with different isothiocyanates in alkaline Al2O3 at room temperature for 1 h affording thiohydantoins in moderate to excellent yields.