期刊文献+
共找到4篇文章
< 1 >
每页显示 20 50 100
醇简便实用的乙酰化方法
1
作者 CarriganMD 高伟 《中国医药工业杂志》 CAS CSCD 北大核心 2002年第10期486-486,共1页
关键词 乙酰化方法 简便法
下载PDF
金雀花提取物正丁醇沉淀部分化学成分研究 被引量:6
2
作者 张妮 穆淑珍 +2 位作者 王家胜 孔琪 余正文 《林产化学与工业》 EI CAS CSCD 北大核心 2015年第3期121-124,共4页
采用乙酰化方法对金雀花中正丁醇沉淀部分的化学成分进行研究。金雀花的地上部分用75%的乙醇提取,乙醇总浸膏用去离子水饱和悬浮,依次用石油醚、乙酸乙酯、正丁醇萃取;其中正丁醇萃取物沉淀部分乙酰化衍生后采用各种柱色谱进行分离纯化... 采用乙酰化方法对金雀花中正丁醇沉淀部分的化学成分进行研究。金雀花的地上部分用75%的乙醇提取,乙醇总浸膏用去离子水饱和悬浮,依次用石油醚、乙酸乙酯、正丁醇萃取;其中正丁醇萃取物沉淀部分乙酰化衍生后采用各种柱色谱进行分离纯化,结合理化性质及光谱数据鉴定化合物结构。从正丁醇沉淀部分分离出4个化合物,分别鉴定为β-谷甾醇、1-三十烷醇、美迪紫檀素及车轴草醇,所有的化合物均为首次从该植物中分离得到。此外,乙酰化反应使得正丁醇沉淀部分的溶解性增加,极性降低,为其他植物中大极性化合物的分离纯化提供参考。 展开更多
关键词 金雀花 乙酰化方法 正丁醇沉淀 化学成分
下载PDF
Study on Deactivation by Sulfur and Regeneration of Pd/C Catalyst in Hydrogenation of N-(3-nitro-4-methoxyphenyl) Acetamide 被引量:1
3
作者 ZHANG Qunfeng LU Jinghui MA Lei LU Chunshan HIU Wei LI Xiaonian 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2013年第6期622-626,共5页
Deactivation of Pd/C catalyst often occurs in liquid hydrogenation using industrial materials. For in-stance, the Pd/C catalyst is deactivated severely in the hydrogenation of N-(3-nitro-4-methoxyphenyl) acetamide. In... Deactivation of Pd/C catalyst often occurs in liquid hydrogenation using industrial materials. For in-stance, the Pd/C catalyst is deactivated severely in the hydrogenation of N-(3-nitro-4-methoxyphenyl) acetamide. In this study, the chemisorption of sulfur on the surface of deactivated Pd/C was detected by energy dispersive spec-trometer and X-ray photoelectron spectroscopy. Sulfur compounds poison the Pd/C catalyst and increase the forma-tion of azo deposit, reducing the activity of catalyst. We report a mild method to regenerate the Pd/C catalyst: wash the deposit by N,N-dimethylformamide and oxidize the chemisorbed sulfur by hot air. The regenerated Pd/C cata-lyst can be reused at least ten runs with stable activity. 展开更多
关键词 Pd/C catalyst HYDROGENATION DEACTIVATION REGENERATION SULFUR
下载PDF
Therapeutic effects of human amniotic epithelial cell transplantation on double-transgenic mice co-expressing APPswe and PS1ΔE9-deleted genes 被引量:3
4
作者 XUE ShouRu CHEN ChongFang +3 位作者 DONG WanLi HUI GuoZhen LIU TianJun GUO Lille 《Science China(Life Sciences)》 SCIE CAS 2012年第2期132-140,共9页
Human amniotic epithelial cells (HAECs), which exhibit characteristics of embryonic and pluripotent stem cells, could be utilized for cell therapy without legal or ethical problems. Double-transgenic (TG) mice (n=20) ... Human amniotic epithelial cells (HAECs), which exhibit characteristics of embryonic and pluripotent stem cells, could be utilized for cell therapy without legal or ethical problems. Double-transgenic (TG) mice (n=20) and wild-type (WT) mice (n=20) were randomly assigned to two groups, respectively. The transplantation group was treated with HAECs and the control group with PBS. A six-radial arm water maze was used to assess spatial memory. Immunofluorescence was utilized to track HAEC survival. Immunohistochemistry was used to determine octamer-binding protein 4 (oct-4) and nanog expression in the HAECs. High-performance liquid chromatography (HPLC) was used to measure acetylcholine levels in the hippocampus. The density of cholinergic neurons in the basal forebrain and nerve fibers in the hippocampus was measured following acetylcholinesterase staining. Results showed that transplanted HAECs survived for at least eight weeks and migrated to the third ventricle without immune rejection. Graft HAECs also expressed the specific stem cell markers oct-4 and nanog. Compared with the control group, HAEC transplantation significantly ameliorated spatial memory deficits in TG mice, as well as increased acetylcholine levels and the number of hippocampal cholinergic neurites. Intracerebroventricular HAEC transplantation improved spatial memory in double-TG mice, and results suggested that increased acetylcholine levels in the hippocampus, released by surviving cholinergic neurites, were responsible for this improvement. 展开更多
关键词 Alzheimer's disease human amniotic epithelial cells spatial memory deficit transgenic mice
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部