seventeen cases of juvenile laryngeal papilloma were investigated for human papiliomavirus (HPV) using in situDNA hybridisation to determine the HPV infection in the disease in Guangdong Chinese . The results showedth...seventeen cases of juvenile laryngeal papilloma were investigated for human papiliomavirus (HPV) using in situDNA hybridisation to determine the HPV infection in the disease in Guangdong Chinese . The results showedthat ten of seventeen cases were positive forHPV-DNA, countering for 58.8%, while the controlwas negative(P<0.005). this implies that the HPV infection is reponsible for the development of the disease inGuangdong area. The authours believe that it is necessaryto classify the disease into two types: juvenile laryngealpaillomas with and without HPV infection,. afterconsidering the history of their parents’ condylomaaccuminatum , the age of onset, the recurrence after treatment, the morphologic feature and the evidence of HPVinfection including the HPA subtypes which is the mostimportant of all.展开更多
文摘seventeen cases of juvenile laryngeal papilloma were investigated for human papiliomavirus (HPV) using in situDNA hybridisation to determine the HPV infection in the disease in Guangdong Chinese . The results showedthat ten of seventeen cases were positive forHPV-DNA, countering for 58.8%, while the controlwas negative(P<0.005). this implies that the HPV infection is reponsible for the development of the disease inGuangdong area. The authours believe that it is necessaryto classify the disease into two types: juvenile laryngealpaillomas with and without HPV infection,. afterconsidering the history of their parents’ condylomaaccuminatum , the age of onset, the recurrence after treatment, the morphologic feature and the evidence of HPVinfection including the HPA subtypes which is the mostimportant of all.
