乳腺硬癌的临床分析

目的 :探讨乳腺硬癌临床特征和生物学行为。方法 :对140例女性原发乳腺硬癌进行回顾性研究。结果 :硬癌占乳腺癌总发病率的2 % ,5年和10年生存率分别为53.6 %和38.4 % ,临床分期和腋窝淋巴结转移是影响预后的重要因素。硬癌X线检出率为71.9% ,细针吸细胞学检出率为57.1%。结论 :乳腺硬癌恶性程度高 ,预后差 ,其X线特点为星形肿块影 ,密度低 ,毛刺多 ,钙化少。细针吸细胞学诊断率低。

细针吸取细胞学诊断32例乳腺硬癌的价值探讨

目的 探讨细针吸取细胞学诊断乳腺硬癌的价值。方法 对 32例乳腺硬癌 (包括混合型 ) (fineneedleaspirationcy tology,FNAC)涂片基本形态学诊断要素进行回顾性研究 ,并对Ⅲ级诊断病例进行原因分析。 结果 乳腺硬癌诊断的敏感性为96 .9% (32 / 33) ,假阴性为 3.1% (1/ 32 )。结论 在细针吸取细胞学诊断中采用”一体化”工作程序 ,抓住拥挤重叠或弥散的细胞排列方式以及游离的细胞浆丰富的细胞、异型裸核等恶性形态学特征 ,可显著提高乳腺硬癌的诊断率。

4例乳腺硬化性腺病冰冻切片诊断为乳腺硬癌的原因分析

乳腺肿块在术前检查不能确定良恶性时,而在术中做冰冻切片观察,可达到快速病理诊断、指导外科医师手术大小和范围的目的。现总结4例乳腺硬化性腺病术中冰冻切片观察误诊为乳腺硬癌,旨在探讨其误诊原因,以提高对该病的准确率,更好的为临床服务。

男性乳腺癌一例报告

患者男,65岁,因左侧乳房无痛性包块二年,增大伴疼痛半年于1993年6月15日入院。检查:体温37℃,脉搏86次/分,呼吸20次/分,血压21/13Kpa,消瘦面容,于左侧乳晕下可扪及直径约4厘米大小的肿块,质硬,边界不清、与皮肤有粘连,皮肤呈桔皮样改变,与胸壁不粘连,可被推动,乳头凹陷,但无溢液、溢血和溃破。左侧腋窝可扪及一枚花生米大小的肿大的淋巴结。入院诊断为男性乳腺癌而行根治术,术后病理报告为乳腺硬癌,左侧腋窝淋巴结二枚阳性。

狼犬乳腺肿瘤切除与术后管理不当后的处理

养殖户对患病动物的治疗很在意,但动物的后期管理,得不到畜主的重视,这是动物治疗过程中普遍的现象,本例犬的乳腺肿瘤切除后,管理不当导致术部发生严重的感染,此病例对兽医外科坚持"三分治疗,七分管理"的原则,值得同广大兽医工作者进一步探讨。

乳腺

~~

Pseudocirrhosis after the Use of Taxanes and Bevacizumab in Metastatic Breast Cancer： Case Reports

Currently, multiple lines of cytotoxic chemotherapy for treatment of metastatic breast cancer are available, and Taxanes, used as monotherapy or in combination with anti-angiogenic drugs, such as Bevacizumab, are one of the most used schemes in clinical practice. These drugs have different side effects and the liver is one of the most affected organs. The objective of this paper is to report three cases of metastatic breast cancer with positive expression of hormone receptors and without amplification of HER-2 protein that were treated with Taxane and Bevacizumab, developed pseudocirrosis probably caused by these drugs and died due to liver failure. It can be drawn from the study that liver failure, as a pseudocirrhosis evolution, is an unusual but lethal event that may occur during the treatment of metastatic breast cancer with Taxanes and Bevacizumab. This warns the importance of diagnostic suspicion of this pathology.