乳腺纤维腺瘤内癌(carcinoma within fibroadnoma,CWFA)指的是上皮成分的癌变,非常少见,文献报道其癌变率为0.02%~0.30%,以小叶癌最常见,导管癌少见。平均发病年龄为42.5岁,比单纯乳腺纤维腺瘤平均年龄晚10-20岁。因此应该注意临床纤维...乳腺纤维腺瘤内癌(carcinoma within fibroadnoma,CWFA)指的是上皮成分的癌变,非常少见,文献报道其癌变率为0.02%~0.30%,以小叶癌最常见,导管癌少见。平均发病年龄为42.5岁,比单纯乳腺纤维腺瘤平均年龄晚10-20岁。因此应该注意临床纤维腺瘤出现在40岁以上的女性,因为他们可能潜在恶性病变的风险。其病理表现为乳腺纤维腺瘤背景中,乳腺导管上皮细胞增生伴有灶状异型细胞增生,病变符合纤维腺瘤内癌,周围组织无癌细胞浸润,组织学形态与普通乳腺癌相似,但各种类型癌的发生率、治疗方式及预后却相差甚远。本文对乳腺纤维腺瘤内癌的相关因素这一热点进行综述。展开更多
Objective: The aim of our study was to evaluate the pathological features of posterior echo attenuation of papillary thyroid microcarcinoma (PTMC) and cystic degeneration of cervical lymph node metastasis. Methods: We...Objective: The aim of our study was to evaluate the pathological features of posterior echo attenuation of papillary thyroid microcarcinoma (PTMC) and cystic degeneration of cervical lymph node metastasis. Methods: We retrospectively evaluated the ultrasound results from 36 cases of PTMC with 20 nodules of cystic degeneration of cervical lymph node metastasis and correlated the results with the histopathologic findings. Results: The preliminary study indicated certain correlation between histopathologic findings and ultrasound results of posterior echo attenuation of papillary thyroid microcarcinoma and cystic degeneration of cervical lymph node metastasis. Conclusion: Posterior echo attenuation detected by ultrasound was associated with fibrous structures in PTMC nodules, while cystic degeneration and papillary changes of cervical lymph node metastasis in PTMC showed liquefactive necrosis, degenerative changes and enlarged follicular of nodular structures.展开更多
文摘乳腺纤维腺瘤内癌(carcinoma within fibroadnoma,CWFA)指的是上皮成分的癌变,非常少见,文献报道其癌变率为0.02%~0.30%,以小叶癌最常见,导管癌少见。平均发病年龄为42.5岁,比单纯乳腺纤维腺瘤平均年龄晚10-20岁。因此应该注意临床纤维腺瘤出现在40岁以上的女性,因为他们可能潜在恶性病变的风险。其病理表现为乳腺纤维腺瘤背景中,乳腺导管上皮细胞增生伴有灶状异型细胞增生,病变符合纤维腺瘤内癌,周围组织无癌细胞浸润,组织学形态与普通乳腺癌相似,但各种类型癌的发生率、治疗方式及预后却相差甚远。本文对乳腺纤维腺瘤内癌的相关因素这一热点进行综述。
文摘Objective: The aim of our study was to evaluate the pathological features of posterior echo attenuation of papillary thyroid microcarcinoma (PTMC) and cystic degeneration of cervical lymph node metastasis. Methods: We retrospectively evaluated the ultrasound results from 36 cases of PTMC with 20 nodules of cystic degeneration of cervical lymph node metastasis and correlated the results with the histopathologic findings. Results: The preliminary study indicated certain correlation between histopathologic findings and ultrasound results of posterior echo attenuation of papillary thyroid microcarcinoma and cystic degeneration of cervical lymph node metastasis. Conclusion: Posterior echo attenuation detected by ultrasound was associated with fibrous structures in PTMC nodules, while cystic degeneration and papillary changes of cervical lymph node metastasis in PTMC showed liquefactive necrosis, degenerative changes and enlarged follicular of nodular structures.