Three well-preserved fossil species ofParandrexis longicornis Lu, Shih & Ren sp. nov., P. agilis Lu, Shih & Ren sp. nov. and P. oblongis Lu, Shih & Ren sp. nov. are described and illustrated from the late Middle Ju...Three well-preserved fossil species ofParandrexis longicornis Lu, Shih & Ren sp. nov., P. agilis Lu, Shih & Ren sp. nov. and P. oblongis Lu, Shih & Ren sp. nov. are described and illustrated from the late Middle Jurassic Jiulongshan Formation of Daohugou in Inner Mongolia Autonomous Region, China. These new species are distinguished from other described species of Parandrexis by body size, head dimension (ratio of length to width), pronotum shape, and antennal characters. Based on new morphological data, we emend the generic diagnosis. These findings support the sexual size dimorphism of parandrexids and suggest a gymnosperm sap feeding habit by Parandrexis.展开更多
AIM:To assess the safety and efficacy of carbon dioxide (CO2) insufflation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:The Cochrane Library, Medical Literature Analysis and Retrieval System O...AIM:To assess the safety and efficacy of carbon dioxide (CO2) insufflation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:The Cochrane Library, Medical Literature Analysis and Retrieval System Online, Excerpta Medica Database, Science Citation Index Expanded, Chinese Biomedical Literature Database, and references in relevant publications were searched up to December 2011 to identify randomized controlled trials (RCTs) comparing CO2 insufflation with air insufflation during ERCP. The trials were included in the review irrespec-tive of sample size, publication status, or language. Study selection and data extraction were performed by two independent authors. The meta-analysis was performed using Review Manager 5.1.6. A random-effects model was used to analyze various outcomes.Sensitivity and subgroup analyses were performed if necessary. R ESULTS:Seven double-blind RCTs involving a total of 818 patients were identified that compared CO2 insufflation (n = 404) with air insufflation (n = 401) during ERCP. There were a total of 13 post-random- ization dropouts in four RCTs. Six RCTs had a high risk of bias and one had a low risk of bias. None of the RCTs reported any severe gas-related adverse events in either group. A meta-analysis of 5 RCTs (n = 459) indicated that patients in the CO2 insufflation group had less post-ERCP abdominal pain and distension for at least 1 h compared with patients in the air insuf-flation group. There were no significant differences in mild cardiopulmonary complications [risk ratio (RR) = 0.43, 95% CI:0.07-2.66, P = 0.36], cardiopulmonary (e.g., blood CO2 level) changes [standardized mean difference (SMD) = -0.97, 95% CI: -2.58-0.63, P = 0.23], cost analysis (mean difference = 3.14, 95% CI:-14.57-20.85, P = 0.73), and total procedure time (SMD = -0.05, 95% CI:-0.26-0.17, P = 0.67) between the two groups. C ONCLUSION:CO2 insufflation during ERCP appears to be safe and reduces post-ERCP abdominal pain and discomfort.展开更多
基金supported by the National Basic Research Program of China (973 Program) (2012CB821906)the National Natural Science Foundation of China (31230065,41272006)+1 种基金Great Wall Scholar and KEY project of the Beijing Municipal Commission of Education (KZ201310028033)Program for Changjiang Scholars and Innovative Research Team in University (IRT13081)
文摘Three well-preserved fossil species ofParandrexis longicornis Lu, Shih & Ren sp. nov., P. agilis Lu, Shih & Ren sp. nov. and P. oblongis Lu, Shih & Ren sp. nov. are described and illustrated from the late Middle Jurassic Jiulongshan Formation of Daohugou in Inner Mongolia Autonomous Region, China. These new species are distinguished from other described species of Parandrexis by body size, head dimension (ratio of length to width), pronotum shape, and antennal characters. Based on new morphological data, we emend the generic diagnosis. These findings support the sexual size dimorphism of parandrexids and suggest a gymnosperm sap feeding habit by Parandrexis.
文摘AIM:To assess the safety and efficacy of carbon dioxide (CO2) insufflation during endoscopic retrograde cholangiopancreatography (ERCP). METHODS:The Cochrane Library, Medical Literature Analysis and Retrieval System Online, Excerpta Medica Database, Science Citation Index Expanded, Chinese Biomedical Literature Database, and references in relevant publications were searched up to December 2011 to identify randomized controlled trials (RCTs) comparing CO2 insufflation with air insufflation during ERCP. The trials were included in the review irrespec-tive of sample size, publication status, or language. Study selection and data extraction were performed by two independent authors. The meta-analysis was performed using Review Manager 5.1.6. A random-effects model was used to analyze various outcomes.Sensitivity and subgroup analyses were performed if necessary. R ESULTS:Seven double-blind RCTs involving a total of 818 patients were identified that compared CO2 insufflation (n = 404) with air insufflation (n = 401) during ERCP. There were a total of 13 post-random- ization dropouts in four RCTs. Six RCTs had a high risk of bias and one had a low risk of bias. None of the RCTs reported any severe gas-related adverse events in either group. A meta-analysis of 5 RCTs (n = 459) indicated that patients in the CO2 insufflation group had less post-ERCP abdominal pain and distension for at least 1 h compared with patients in the air insuf-flation group. There were no significant differences in mild cardiopulmonary complications [risk ratio (RR) = 0.43, 95% CI:0.07-2.66, P = 0.36], cardiopulmonary (e.g., blood CO2 level) changes [standardized mean difference (SMD) = -0.97, 95% CI: -2.58-0.63, P = 0.23], cost analysis (mean difference = 3.14, 95% CI:-14.57-20.85, P = 0.73), and total procedure time (SMD = -0.05, 95% CI:-0.26-0.17, P = 0.67) between the two groups. C ONCLUSION:CO2 insufflation during ERCP appears to be safe and reduces post-ERCP abdominal pain and discomfort.