Reaction of 2,4-di-Eert-butyl-phenol,ethylenediamine and formaldehyde （37% solution in water）in 2:1:5molar ratio in methanol afforded the 1,2-bis[3-（6,8-di-tert-butyl-3,4-dihydro-2[H]-1,3-benzoxazine）-yl]ethane in...Reaction of 2,4-di-Eert-butyl-phenol,ethylenediamine and formaldehyde （37% solution in water）in 2:1:5molar ratio in methanol afforded the 1,2-bis[3-（6,8-di-tert-butyl-3,4-dihydro-2[H]-1,3-benzoxazine）-yl]ethane in high yields.This compound was fully characterized by elemental analysis,1H NMR,MS,and IR spectroscopies.The crystal structure of the title compound was determined by X-ray diffraction method.It crystallizes in triclinic,space group P（1）,a=0.5727（2）,b=0.9268（3）,c=1.4666（4）nm,a=88.12（1）°,β=88.54（1）°,γ=80.82（1）°,V=0.7679（4）nm3,Z=1,DC=1.126Mg·m-3,F（000）=286,μ（MoKα）=0.69cm-1,R=0.048,wR=0.140.This compound had a centrosymmetrical structure.展开更多
Ring closure reactions of 1, 6-diamino-4- （4-chlorophenyl）-2-oxopyridine-3, 5-dicarbonitrile （1） with various 1, 3-dielectrophiles namely, diethyl malonate, ethyl cthoxymethylene cyanoacetate, 2-cyano-3, 3-bis（me...Ring closure reactions of 1, 6-diamino-4- （4-chlorophenyl）-2-oxopyridine-3, 5-dicarbonitrile （1） with various 1, 3-dielectrophiles namely, diethyl malonate, ethyl cthoxymethylene cyanoacetate, 2-cyano-3, 3-bis（methylthio） acrylonitril, dimethyl acetylenedicarboxylate, dehydroacetic acid, chromon- 3-carbonitrile and 3-formylchromone led to the formation of the target bihetherocylicl,2,4-triazepines. The effect of 3-phenylazo-2, 4-pentandione, ethyl ct-cyano-ct-phenylazoacetate and 3, 1-benzoxazin-4-one derivative on 1 was also discussed.展开更多
文摘Reaction of 2,4-di-Eert-butyl-phenol,ethylenediamine and formaldehyde （37% solution in water）in 2:1:5molar ratio in methanol afforded the 1,2-bis[3-（6,8-di-tert-butyl-3,4-dihydro-2[H]-1,3-benzoxazine）-yl]ethane in high yields.This compound was fully characterized by elemental analysis,1H NMR,MS,and IR spectroscopies.The crystal structure of the title compound was determined by X-ray diffraction method.It crystallizes in triclinic,space group P（1）,a=0.5727（2）,b=0.9268（3）,c=1.4666（4）nm,a=88.12（1）°,β=88.54（1）°,γ=80.82（1）°,V=0.7679（4）nm3,Z=1,DC=1.126Mg·m-3,F（000）=286,μ（MoKα）=0.69cm-1,R=0.048,wR=0.140.This compound had a centrosymmetrical structure.
文摘Ring closure reactions of 1, 6-diamino-4- （4-chlorophenyl）-2-oxopyridine-3, 5-dicarbonitrile （1） with various 1, 3-dielectrophiles namely, diethyl malonate, ethyl cthoxymethylene cyanoacetate, 2-cyano-3, 3-bis（methylthio） acrylonitril, dimethyl acetylenedicarboxylate, dehydroacetic acid, chromon- 3-carbonitrile and 3-formylchromone led to the formation of the target bihetherocylicl,2,4-triazepines. The effect of 3-phenylazo-2, 4-pentandione, ethyl ct-cyano-ct-phenylazoacetate and 3, 1-benzoxazin-4-one derivative on 1 was also discussed.
