Grignard reagents were prepared from the starting materials 1-bromo-3,5-difluorobenzene,1-bromo-2,4-difluorobenzene andbromo-3,4-difluorobenzene respectively,then reacted with diethyl carbonate to form magnesium tris(...Grignard reagents were prepared from the starting materials 1-bromo-3,5-difluorobenzene,1-bromo-2,4-difluorobenzene andbromo-3,4-difluorobenzene respectively,then reacted with diethyl carbonate to form magnesium tris(difluoropheny)methanol,and methacryloyl chloride was added dropwise to abtain tris(difluorophenyl)methyl methacrylates.The target products were synthesized in high overall yield(67～74%)with"one-pot"method.Structures of the compounds were comfirmed by IR,1HNMR,13CNMR and elemental analysis,and methanolysis was also studied.展开更多
文摘Grignard reagents were prepared from the starting materials 1-bromo-3,5-difluorobenzene,1-bromo-2,4-difluorobenzene andbromo-3,4-difluorobenzene respectively,then reacted with diethyl carbonate to form magnesium tris(difluoropheny)methanol,and methacryloyl chloride was added dropwise to abtain tris(difluorophenyl)methyl methacrylates.The target products were synthesized in high overall yield(67～74%)with"one-pot"method.Structures of the compounds were comfirmed by IR,1HNMR,13CNMR and elemental analysis,and methanolysis was also studied.
