This paper is based on Einstein’s supposition about crystal lattice vibration, which states that when Einstein’s temperature ΘE is not less than the crystal temperature T but less than 2T, the expression of crystal...This paper is based on Einstein’s supposition about crystal lattice vibration, which states that when Einstein’s temperature ΘE is not less than the crystal temperature T but less than 2T, the expression of crystal molar heat capacity changes to the Dulong-Petit equation Cv=3R. Thereby this equation can explain why crystal molar heat capacity equals about 3R not only at low temperatures but also at normal temperatures for many kinds of metals. It can be calculated that the nonlinear interaction among atoms contributes to the molar heat capacity using the coefficient of expansion β and the Grüneisen constant γ. The result is that the relative error between the theoretical and the experimental value of the molar heat capacity is reduced greatly for many kinds of metals, especially for metals of IA. The relative error can be cut by about 17%.展开更多
Ruthenium complexes which can bind to DNA via electrostatic and intercalation interactions producing strong luminescence have become ideal candidates for DNA staining. However, some of them such as Ru(phen)_3Cl_2 and ...Ruthenium complexes which can bind to DNA via electrostatic and intercalation interactions producing strong luminescence have become ideal candidates for DNA staining. However, some of them such as Ru(phen)_3Cl_2 and Ru(phen)_2(dppz)Cl_2 could hardly cross the cellular membrane of live cells which limited their further interaction with DNA in live cells. To solve this problem, a potential approach is to find a proper vehicle for loading and delivery of these ruthenium complexes into live cells.Mesoporous silica nanoparticles(MSNs) with non-toxicity and good biocompatibility can be good candidates. More importantly,ruthenium complexes with positively charge could be loaded on negatively charged MSNs via electrostatic attractions to form MSNs-Ru hybrid. In vitro test demonstrated that MSNs had no side effects on the interactions between Ru complexes and DNA.Furthermore, it is found that the MSNs-Ru hybrid can enter into living human cervical cancer cells HeLa and stain the DNA while the corresponding ruthenium complexes alone could hardly cross the cellular membrane in the control experiment, demonstrating MSNs can be employed to be an efficient ruthenium complexes delivery nanomaterial for live cell staining.展开更多
Chirality is a unique phenomenon in nature. Chiral interactions play an important role in biological and physiological process- es, which provides much inspiration for scientists to develop cbiral materials. As a brea...Chirality is a unique phenomenon in nature. Chiral interactions play an important role in biological and physiological process- es, which provides much inspiration for scientists to develop cbiral materials. As a breakthrough from traditional materials, bi- ointerface materials based on chiral polymers have attracted increasing interest over the past few years. Such materials ele- gantly combine the advantages of chiral surfaces and traditional polymers, and provide a novel solution not only for the inves- tigation of chiral interaction mechanisms but also for the design of biomaterials with diverse applications, such as in tissue en- gineering and biocompatible materials, bioregulation, chiral separation and chiral sensors. Herein, we summarize recent ad- vances in the study of chiral effects and applications of chiral polymer-based biointerface materials, and also present some challenges and perspectives.展开更多
文摘This paper is based on Einstein’s supposition about crystal lattice vibration, which states that when Einstein’s temperature ΘE is not less than the crystal temperature T but less than 2T, the expression of crystal molar heat capacity changes to the Dulong-Petit equation Cv=3R. Thereby this equation can explain why crystal molar heat capacity equals about 3R not only at low temperatures but also at normal temperatures for many kinds of metals. It can be calculated that the nonlinear interaction among atoms contributes to the molar heat capacity using the coefficient of expansion β and the Grüneisen constant γ. The result is that the relative error between the theoretical and the experimental value of the molar heat capacity is reduced greatly for many kinds of metals, especially for metals of IA. The relative error can be cut by about 17%.
基金supported by the Scientific Research Foundation of Northwest A&F University (Z111021103, Z111021107)the National Natural Science Foundation of China (21472016, 21272030, 21476185)
文摘Ruthenium complexes which can bind to DNA via electrostatic and intercalation interactions producing strong luminescence have become ideal candidates for DNA staining. However, some of them such as Ru(phen)_3Cl_2 and Ru(phen)_2(dppz)Cl_2 could hardly cross the cellular membrane of live cells which limited their further interaction with DNA in live cells. To solve this problem, a potential approach is to find a proper vehicle for loading and delivery of these ruthenium complexes into live cells.Mesoporous silica nanoparticles(MSNs) with non-toxicity and good biocompatibility can be good candidates. More importantly,ruthenium complexes with positively charge could be loaded on negatively charged MSNs via electrostatic attractions to form MSNs-Ru hybrid. In vitro test demonstrated that MSNs had no side effects on the interactions between Ru complexes and DNA.Furthermore, it is found that the MSNs-Ru hybrid can enter into living human cervical cancer cells HeLa and stain the DNA while the corresponding ruthenium complexes alone could hardly cross the cellular membrane in the control experiment, demonstrating MSNs can be employed to be an efficient ruthenium complexes delivery nanomaterial for live cell staining.
基金the financial support of the National Natural Science Foundation of China(21104061,21275114,91127027,51173142)the National Basic Research Program of China(2013CB933002)the Fundamental Research Funds for the Central Universities(2013-YB-026)
文摘Chirality is a unique phenomenon in nature. Chiral interactions play an important role in biological and physiological process- es, which provides much inspiration for scientists to develop cbiral materials. As a breakthrough from traditional materials, bi- ointerface materials based on chiral polymers have attracted increasing interest over the past few years. Such materials ele- gantly combine the advantages of chiral surfaces and traditional polymers, and provide a novel solution not only for the inves- tigation of chiral interaction mechanisms but also for the design of biomaterials with diverse applications, such as in tissue en- gineering and biocompatible materials, bioregulation, chiral separation and chiral sensors. Herein, we summarize recent ad- vances in the study of chiral effects and applications of chiral polymer-based biointerface materials, and also present some challenges and perspectives.
