In order to realize interoperability to a large number of autonomous and heterogeneous information sources with high efficiency, an agent-based multi-broker architecture （AMA）-HustEven, is constructed. A group of br...In order to realize interoperability to a large number of autonomous and heterogeneous information sources with high efficiency, an agent-based multi-broker architecture （AMA）-HustEven, is constructed. A group of broker agents are designed to provide brokering services in a peer-to-peer （P2P） manner for the non- broker agents （user agents, resource agents, query agents）. Thus, the scalability and robustness of the system are enhanced. Ontology is also used by the broker agents for facilitating interoperability among all the agents in HustEven. Unlike any other AMAs, an interdomain ontology is built in this system to represent the relationships among the common concepts in the innerdomain ontologies. Therefore, a broker forwards the queries only to the other related brokers according to the interdomain ontology and the communication overhead among the brokers is reduced. Obviously, the application of the interdomain ontology enables a broker to fully take advantage of the multi-broker architecture. The experimental results show that the HustEven performs more efficiently than any other existing systems.展开更多
基金国家自然科学基金青年基金项目“基于本体方法的我国上市甲乙肝疫苗相关不良反应数据挖掘与建模分析”(61801067)重庆市教育委员会科学技术研究重点项目“卡介苗两种用途下相应不良反应信息的本体化表征与建模分析”(KJZD-K202000603)+4 种基金中国医学科学院中央级公益性科研院所基本科研业务费专项资金资助,“国家卫生健康委员会肺脏免疫性疾病诊治重点实验室”建设项目(2019PT320003)University of Michigan Medical School Global Reach FundMichigan Medicine-Peking University Health Sciences Center Joint Institute for Clinical and Translational Research“Systemic Investigation of the Microbiome-host interactions in H.pylori-associated Gastric Cancer Patients”(U063430,BMU2019JI010)国家重点研发计划精准医学研究专项“疾病表型组-实验组学数据分析、注释与整合”(2017YFC0908404)中国医学科学院医学与健康科技创新工程项目“生物医学本体支持的通用数据元素表示和应用系统建设”(2018-I2M-AI-009)。
基金The National Natural Science Foundation of China(No60673128)
文摘In order to realize interoperability to a large number of autonomous and heterogeneous information sources with high efficiency, an agent-based multi-broker architecture （AMA）-HustEven, is constructed. A group of broker agents are designed to provide brokering services in a peer-to-peer （P2P） manner for the non- broker agents （user agents, resource agents, query agents）. Thus, the scalability and robustness of the system are enhanced. Ontology is also used by the broker agents for facilitating interoperability among all the agents in HustEven. Unlike any other AMAs, an interdomain ontology is built in this system to represent the relationships among the common concepts in the innerdomain ontologies. Therefore, a broker forwards the queries only to the other related brokers according to the interdomain ontology and the communication overhead among the brokers is reduced. Obviously, the application of the interdomain ontology enables a broker to fully take advantage of the multi-broker architecture. The experimental results show that the HustEven performs more efficiently than any other existing systems.
