Objective To survey the exchange rate of the sodium ion and the magnesium ion in the erythrocyte of patients with the essential hypertension and the cerebral hemorrhage and the cerebral infarction and to probe the rel...Objective To survey the exchange rate of the sodium ion and the magnesium ion in the erythrocyte of patients with the essential hypertension and the cerebral hemorrhage and the cerebral infarction and to probe the relationship with Na +/Mg 2+ ion and endotheinlin -1.Methods The erythrocyte concentration of the sodium and magnesium ion were measured by the flame assay of atomic absorption spectropholometry in 23 patients with EH and 21 patients with CH and 34 patients with CI. The maximum rates of total magnesium efflux(VTmax) and the sodium-independent magnesium efflux (VNImax) and the sodium-dependent magnesium efflux(VNDmax) were determined . The plasma endothenlin-1 was measured in all patients Results (1)There were no difference for the plasma sodium and the plasma magnesium in patients with EH and the normal control (P> 0.05). The EH cases showed significantly a lower EMC and a higher VNDmax and VTmax than normal controls (P<0.05). (2)The CH and CI cases showed significantly higher in ESC and lower EMC and faster VNDmax and VTmax than normal controls. There were the significantly negative correlated with EMC and ET and the significantly positive correlated with the EMC and the sodium ion in erythrocyte in these cases. Conclusion The rapid exchange rate of the sodium ion and the magnesium ion in erythrocyte leads the higher in sodium ion and lower magnesium ion in erythrocyte, meanwhile the ET influence these effect.展开更多
目的对所有症状限制性最大极限心肺运动试验(CPET)的呼吸交换率(RER)相关数据进行再分析,以期探讨CPET中RER为何水平时应该作为终止试验的参考依据。方法第4版Principles of Exercise Testing and Interpretation一书中收录的85例受试...目的对所有症状限制性最大极限心肺运动试验(CPET)的呼吸交换率(RER)相关数据进行再分析,以期探讨CPET中RER为何水平时应该作为终止试验的参考依据。方法第4版Principles of Exercise Testing and Interpretation一书中收录的85例受试者以标准连续递增功率方案共完成112例次CPET,其中完成RER记录的有102例次。计算并比较同一个CPET中峰值运动时与RER≥1.10、1.15、1.20时的运动时间、功率、收缩压、心率、呼吸频率、分钟通气量、二氧化碳排出量、摄氧量、氧脉搏和RER。结果 102例次CPET的峰值RER[范围0.86～1.77,(1.21±0.16)],其中四分之三至半数CPET的峰值RER≥1.10、1.15和1.20;但同时峰值RER<1.0者也有7例次。峰值RER≥1.10的77例次CPET,其峰值运动时与RER≥1.10时的运动时间、功率、心率、呼吸频率、分钟通气量、二氧化碳排出量、摄氧量、氧脉搏和RER比较,差异有统计学意义(P<0.05)。CPET峰值RER≥1.15者60例次,峰值运动时与RER≥1.15时的运动时间、功率、心率、呼吸频率、分钟通气量、二氧化碳排出量和RER比较,差异有统计学意义(P<0.05)。CPET峰值RER≥1.20者50例次,峰值运动时与RER≥1.20时的运动时间、功率、心率、呼吸频率、分钟通气量和RER比较,差异有统计学意义(P<0.05)。结论个体化症状限制性最大极限CPET大多数患者峰值RER达到或者超过1.10,但也有很多患者没有达到此值;不能以某特定RER值作为CPET的绝对标准。CPET临床实践中强调严密监护保安全前提下的"症状限制",既不能以达到特定RER值终止试验,而低估患者整体功能状态;也不能以未达到特定RER值来否定患者CPET的极限运动状态,从而产生过度运动风险的可能,为此本研究提出了Max试验的方法以验证CPET是否为极限运动。展开更多
文摘Objective To survey the exchange rate of the sodium ion and the magnesium ion in the erythrocyte of patients with the essential hypertension and the cerebral hemorrhage and the cerebral infarction and to probe the relationship with Na +/Mg 2+ ion and endotheinlin -1.Methods The erythrocyte concentration of the sodium and magnesium ion were measured by the flame assay of atomic absorption spectropholometry in 23 patients with EH and 21 patients with CH and 34 patients with CI. The maximum rates of total magnesium efflux(VTmax) and the sodium-independent magnesium efflux (VNImax) and the sodium-dependent magnesium efflux(VNDmax) were determined . The plasma endothenlin-1 was measured in all patients Results (1)There were no difference for the plasma sodium and the plasma magnesium in patients with EH and the normal control (P> 0.05). The EH cases showed significantly a lower EMC and a higher VNDmax and VTmax than normal controls (P<0.05). (2)The CH and CI cases showed significantly higher in ESC and lower EMC and faster VNDmax and VTmax than normal controls. There were the significantly negative correlated with EMC and ET and the significantly positive correlated with the EMC and the sodium ion in erythrocyte in these cases. Conclusion The rapid exchange rate of the sodium ion and the magnesium ion in erythrocyte leads the higher in sodium ion and lower magnesium ion in erythrocyte, meanwhile the ET influence these effect.
文摘目的对所有症状限制性最大极限心肺运动试验(CPET)的呼吸交换率(RER)相关数据进行再分析,以期探讨CPET中RER为何水平时应该作为终止试验的参考依据。方法第4版Principles of Exercise Testing and Interpretation一书中收录的85例受试者以标准连续递增功率方案共完成112例次CPET,其中完成RER记录的有102例次。计算并比较同一个CPET中峰值运动时与RER≥1.10、1.15、1.20时的运动时间、功率、收缩压、心率、呼吸频率、分钟通气量、二氧化碳排出量、摄氧量、氧脉搏和RER。结果 102例次CPET的峰值RER[范围0.86～1.77,(1.21±0.16)],其中四分之三至半数CPET的峰值RER≥1.10、1.15和1.20;但同时峰值RER<1.0者也有7例次。峰值RER≥1.10的77例次CPET,其峰值运动时与RER≥1.10时的运动时间、功率、心率、呼吸频率、分钟通气量、二氧化碳排出量、摄氧量、氧脉搏和RER比较,差异有统计学意义(P<0.05)。CPET峰值RER≥1.15者60例次,峰值运动时与RER≥1.15时的运动时间、功率、心率、呼吸频率、分钟通气量、二氧化碳排出量和RER比较,差异有统计学意义(P<0.05)。CPET峰值RER≥1.20者50例次,峰值运动时与RER≥1.20时的运动时间、功率、心率、呼吸频率、分钟通气量和RER比较,差异有统计学意义(P<0.05)。结论个体化症状限制性最大极限CPET大多数患者峰值RER达到或者超过1.10,但也有很多患者没有达到此值;不能以某特定RER值作为CPET的绝对标准。CPET临床实践中强调严密监护保安全前提下的"症状限制",既不能以达到特定RER值终止试验,而低估患者整体功能状态;也不能以未达到特定RER值来否定患者CPET的极限运动状态,从而产生过度运动风险的可能,为此本研究提出了Max试验的方法以验证CPET是否为极限运动。
