米索前列醇不同给药途径减少产后出血及产露时间的效果评价

目的:探讨米索前列醇直肠和宫腔两种不同给药途径在减少产后出血量及缩短产露时间的效果。方法:选择2003年住院阴道分娩300例,剖宫产300例作为两个观察组;将2001年住院阴道分娩300例,剖宫产300例作为两个对照组,进行观察对比。结果:2h内出血量及24h出血量及产露时间,单纯缩宫素组两组及米索+缩宫素两组比较有极显著差异性(P<0.01);同时发现阴道分娩与剖宫产两组的2h及24h出血量有显著差异性,而产露时间基本相等。结论:米索前列醇具有比催产素更强的子宫收缩作用,能减少产后出血量及缩短产露时间,根据不同的分娩方式给予不同的给药途径均能取得较好的效果。

不同给药途径预防产后出血的对比分析

目的:探讨米索前列醇直肠和口服两种不同给药途径在减少产后出血量的效果及安全性。方法:选2009年1月～6月在我院住院阴道分娩的产妇100例,随机分为口服给药组合乎直肠给药组,每组100例。结果:直肠给药组的出血量明显少于口服给药组。两组都无明显不良反应。结论:米索前列醇预防产后出血简便、安全、高效,是应用前景广阔的预防产后出血药物。

Spatial and temporal variability of open biomass burning in Northeast China from 2003 to 2017

Open biomass burning(OBB)has a significant impact on the heavy haze pollution in Northeast China(NEC)in recent years,which requires the investigation of the spatiotemporal variations of OBB with different vegetation types to better monitor and control OBB in NEC.The MODIS C6 fire and land cover products,together with the emissions inventory from the Global Fire Assimilation System,were used in this study.The changes in the total number of MODIS fire points in NEC from 2003 to 2017 demonstrated a fluctuating but generally rising trend,with a peak during 2013–2017.Most fire points concentrated in two key periods,i.e.March–April(37%)and October–November(46%).The total number of crop residue burnings in March–April was basically slightly fluctuating and increased sharply from 2013,whilst the number in October–November had a fluctuating and upward trend until 2015,when a decline appeared.The amount of OBB in March–April was higher than that in October–November during 2016–17.OBB in Heilongjiang Province comprised a major proportion of all fires,which accounted for 70.7%from 2003 to 2017;however,the proportion was only 66.2%during 2013–2017.The largest proportion of all fires was in cropland(90.8%),then forest(5.3%)and grassland(3.1%).The cumulative emissions of fine particulate matter,nitrogen oxides,and ammonia from agricultural open burning in NEC reached 78.43 Gg,24.9 Gg,and 13.7 Gg for March–April during 2013–17,respectively,which were close to those in October–November.

Voluntary Disclosure and the Type of Product Market Competition： Capacity vs. Price

This paper investigates empirically the effect of different types of product market competition on levels of voluntary disclosure of proprietary information in financial markets. The author proposes that there are two types of strategic interaction settings relevant to disclosure： capacity competition and price competition. Capacity competition drives firms to disclose more information to attain financial market valuation-related benefits, while price competition drives them to disclose less to protect long-term product market advantages. The author finds that the type of product market competition affects the level of voluntary disclosure over and above the finn＇s external financing needs documented in the previous literature. That is, firms engaged in capacity competition disclose relatively more information than those in price competition. Further analysis shows that capacity competition firms disclose more information than no-strategic-interaction benchmark firms but that price competition firms do not disclose less information than the benchmark firms.

Optimization of drilling and blasting operations in an open pit mine——the SOMAIR experience

Drilling and blasting play vital roles in opencast mining. These operations not only affect the cost of production directly but as well and significantly, the overall operational costs. This research was carried out to find a possible way of optimizing the drilling and blasting operations in an open pit mine of Somair (Société des Mines de l’Air), in the Niger Republic. In order to optimize the drilling operation, the time taken by two drilling machines to accomplish the same task was analyzed statistically. The result indicates that the Down the Hole Hammer Drilling Rig (DMNo406) is more efficient than the Drill Master (DM405). The relative unit consumption of two explosives (Explus and Nitram 9), when used under the same operating conditions, were also considered and the results indicate Explus to be more economical per unit consumption with a range of 0.15 g/t–0.183 g/t, when compared with Nitram 9 with a unit consumption range of 0.19 g/t-0.24 g/t in the study area.

Improving performance of open-pit mine production scheduling problem under grade uncertainty by hybrid algorithms

One of the surface mining methods is open-pit mining,by which a pit is dug to extract ore or waste downwards from the earth’s surface.In the mining industry,one of the most significant difficulties is long-term production scheduling(LTPS)of the open-pit mines.Deterministic and uncertainty-based approaches are identified as the main strategies,which have been widely used to cope with this problem.Within the last few years,many researchers have highly considered a new computational type,which is less costly,i.e.,meta-heuristic methods,so as to solve the mine design and production scheduling problem.Although the optimality of the final solution cannot be guaranteed,they are able to produce sufficiently good solutions with relatively less computational costs.In the present paper,two hybrid models between augmented Lagrangian relaxation(ALR)and a particle swarm optimization(PSO)and ALR and bat algorithm(BA)are suggested so that the LTPS problem is solved under the condition of grade uncertainty.It is suggested to carry out the ALR method on the LTPS problem to improve its performance and accelerate the convergence.Moreover,the Lagrangian coefficients are updated by using PSO and BA.The presented models have been compared with the outcomes of the ALR-genetic algorithm,the ALR-traditional sub-gradient method,and the conventional method without using the Lagrangian approach.The results indicated that the ALR is considered a more efficient approach which can solve a large-scale problem and make a valid solution.Hence,it is more effectual than the conventional method.Furthermore,the time and cost of computation are diminished by the proposed hybrid strategies.The CPU time using the ALR-BA method is about 7.4%higher than the ALR-PSO approach.

Annual risk reporting of listed companies in Malaysia

This study examines risk reporting in annual reports of Malaysian listed companies. The mandatory and voluntary disclosures of risk information are analyzed and the authors examine whether a relationship exists between company size, leverage, and industry type and risk disclosure levels. 150 listed companies from five industries are selected as sample. Content analysis and risk disclosure index of dichotomous measurement are used in data collection. Overall the results indicate that level of risk information disclosed in the annual reports is still minimal. OLS （Ordinary least squares） regression analysis indicates that the level of risk information disclosure is positively associated with size and not with leverage. However, a mixed result has been found for industry type; where only property industry shows a significant relationship with level of risk disclosure, and not for the other industries. This study contributes to financial reporting literature in relation to risk reporting, particularly the practice of Malaysian companies. Findings from this study are also useful to regulators and accounting standard setting body to assess the level of compliance to regulations and standards relating to risk reporting by these companies. More studies are required to further understand the importance of risk information disclosure, such as risk disclosure within specific industry, cross-country studies and usefulness of risk information disclosure from the stakeholders＇ perspectives.

Improvement of Lagrangian relaxation performance for open pit mines constrained long-term production scheduling problem

Constrained long-term production scheduling problem(CLTPSP) of open pit mines has been extensively studied in the past few decades due to its wide application in mining projects and the computational challenges it poses become an NP-hard problem.This problem has major practical significance because the effectiveness of the schedules obtained has strong economical impact for any mining project.Despite of the rapid theoretical and technical advances in this field,heuristics is still the only viable approach for large scale industrial applications.This work presents an approach combining genetic algorithms(GAs) and Lagrangian relaxation(LR) to optimally determine the CLTPSP of open pit mines.GAs are stochastic,parallel search algorithms based on the natural selection and the process of evolution.LR method is known for handling large-scale separable problems; however,the convergence to the optimal solution can be slow.The proposed Lagrangian relaxation and genetic algorithms(LR-GAs) combines genetic algorithms into Lagrangian relaxation method to update the Lagrangian multipliers.This approach leads to improve the performance of Lagrangian relaxation method in solving CLTPSP.Numerical results demonstrate that the LR method using GAs to improve its performance speeding up the convergence.Subsequently,highly near-optimal solution to the CLTPSP can be achieved by the LR-GAs.

Sustainable development of lignite production on open cast mines in Serbia

Energy sector represents a key industrial branch for national, environmental and economic success. With its exclusive access to domestic deposits, lignite industry represents a guarantor of reliable raw materials, offering long-term supply security based on verified reserves. Currently operated coalmines in Serbia (Kolubara and Kostolac) have production around 36 million tons of lignite, and over 108 million m3 of overburden. Consequently, sustainability of lignite production requires cost reduction and environmental protection, as well as capacity increase. In order to rationalise, and increase efficiency of Serbian lignite mines, it is necessary to focus the activities on major issues shown within the triangle of energy policy objectives (security of supply, competi- tive prices and environmental protection). Production process optimisation singled out several special programs. Equipment revi- talization and modernization is necessary taking into account that majority of the currently operated machinery has a life up to 25 years. Production process automation would enable high level of technical operation in the field of open cast mines management. Lack of coal quality uniformity is the permanent problem resulting by great amounts of coal reserves to be used uneconomically. Planning and training at all levels and finally cooperative software for business procedures and work order management. The measures suggested are a key precondition for maintaining competitive position of lignite production on international level.

Toxic hepatitis in occupational exposure to solvents

The liver is the main organ responsible for the metabolism of drugs and toxic chemicals, and so is the primary target organ for many organic solvents. Work activities with hepatotoxins exposures are numerous and, moreover, organic solvents are used in various industrial processes. Organic solvents used in different industrial processes may be associated with hepatotoxicity. Several factors contribute to liver toxicity; among these are: species differences, nutritional condition, genetic factors, interaction with medications in use, alcohol abuse and interaction, and age. This review addresses the mechanisms of hepatotoxicity. The main pathogenic mechanisms responsible for functional and organic damage caused by solvents are: inflammation, dysfunction of cytochrome P450, mitochondrial dysfunction and oxidative stress. The health impact of exposure to solvents in the workplace remains an interesting and worrying question for professional health work.

Maize Seeds Submitted to Thermotherapy and Analyzed by Dynamic Speckle

The quality of the seeds used for sowing is fundamental for a high productivity and quality of the crop. Therefore, eradicating pathogens is essential for the plant to develop in the best possible way. The eradication of those pathogens can be accomplished by means of treatments that consist of the application of substances to the seeds or by performing physical procedures. Thermotherapy is a physical treatment, in which the seed is exposed to a given thermal energy, such as heated air or steam, and can be highly efficient for controlling those pathogens, in addition to reducing environmental damage and costs. The present work aimed to evaluate the efficiency of thermotherapy in two ways： wet heat （water） and dry heat （water vapor）, both at 60 °C, alternating the exposure time to the thermal sources. The treatment with humid heat with a time of exposure of 5 min was the most efficient, since it presented higher germination percentages （83%） and less occurrence of Fusarium sp. （33%）. It was observed that the most efficient thermotherapy is in the control of Fusarium, the most aggressive is for the quality of the seed. The quality of the treatments was evaluated through standard methodologies, according to the rules for seed analysis, such as germination and sanitation tests. Biospeckle laser was used to identify the microbial activity in these seeds, through activity maps generated by laser speckle contrast analysis （LASCA） processing. In this way, the research involving thermotherapy can be done by varying the temperature and the time of exposure to obtain values that considerably reduce the pathogenic agents and preserve the quality, in order to maintain the values of germination and vigor acceptable for commercialization.