Objectives:This study aimed to identify facilitators and barriers to parent-child communication in pediatric palliative care,providing insights for medical professionals developing targeted interventions to enhance pa...Objectives:This study aimed to identify facilitators and barriers to parent-child communication in pediatric palliative care,providing insights for medical professionals developing targeted interventions to enhance parent-child communication and improve its effectiveness.Methods:Whittemore and Knafl’s integrative review method was employed to guide a systematic search for literature in six databases(Medline,Embase,CINAHL Complete,PsycINFO,Web of Science,and Cochrane Library).Peer-reviewer articles published in the English language from inception to December 2023.All of the identified studies were screened,extracted,and analyzed independently by two researchers.Results:Twenty-four articles were included.Thefindings of the relevant studies were analyzed using thematic analysis.Four themes were identified as facilitators:legacy-making,resilience training programs,guidance from the healthcare team,and positive communication.Seven themes were identified as barriers:denial,being unprepared and evasive,mutual protection,being overwhelmed by painful emotions and overloaded with information,incorrect views of medical professionals and parents,negative communication,and cultural context.Conclusions:Parents and professionals should avoid myths about protecting the child and encourage open communication that respects the child’s wishes.The specialized pediatric palliative care team should carefully monitor parent-child communication,determine if any obstacles exist,and design more interventions to enhance it.展开更多
Objective The entorhino-hippocampal pathway is the major excitatory input from neurons of the entorhinal cortex on both ipsilateral and contralateral hippocampus/dentate gyrus. This fiber tract consists of the alvear ...Objective The entorhino-hippocampal pathway is the major excitatory input from neurons of the entorhinal cortex on both ipsilateral and contralateral hippocampus/dentate gyrus. This fiber tract consists of the alvear path, the perforant path and a crossed commissural projection. In this study, the histogenesis and development of the various subsets of the entorhino-hippocampal projection have been investigated. Methods Dil, DiO and fast blue tracing as well as anti-calretinin immunocytochemistry were carried out with prenatal and postnatal rats at different ages. Results The alvear path and the commissural pathway started to develop as early as embryonic day （E） 16, while the first perforant afferents reached the stratum lacunosum-moleculare of the hippocampus at E 17 and the outer molecular layer of dentate gyrus at postnatal day （P） 2, respectively. Retrograde tracing with DiI identified entorhinal neurons in layer II to IV as the origin of entorhino-hippocampal pathway. Furthermore, anti-calretinin immunocytochemistry revealed transitory Cajal- Retzius （CR） cells in the stratum lacunosum-moleculare of the hippocampus from as early as E 16. DiI labeling of entorhinal cortex fibers and combined calretinin-immunocytochemistry showed a close association between CR cells and entorhinal afferents. Conclusion The subsets of entorhino-hippocampal pathway appear in the developmental hippocampus during El6 - P2. The temporal and spatial relationship between CR cell and perforant afferent suggests the role of this cell type as a guiding cue for entorhinal afferents at early cortical development.展开更多
The differences in growth period and seeding to heading duration of both parents of Tongyoujing 1 are 4-6 and 3-5 d, respectively. Plant height of the male parent was 6-8 cm higher than that of the female parent, and ...The differences in growth period and seeding to heading duration of both parents of Tongyoujing 1 are 4-6 and 3-5 d, respectively. Plant height of the male parent was 6-8 cm higher than that of the female parent, and blooming time of the male parent was 30-60 min earlier than that of the female parent. The seed pro-duction technology points of Tongyoujing 1 include appropriate seeding （the differ-ence in sowing period of both parents is 3-5 d）, timely transplanting, reasonable layout （ratio of rows between both parents is 2：（6-8））, strengthening variety isolation, scientific fertilizer and water management （high fertilization for male parent and ade-quate fertilization for female parent）, reasonably regulating flowering period （to pro-mote flower synchronization）, artificial pollination （to improve outcrossing rate）, paying attention to miscel aneous plant removal and pest control and timely harvest.展开更多
Although reviewers of Tremblay＇s play For the Pleasure of Seeing Her Again （1998） focus on the monologues of the angry mother who rants about everyday concerns for the well-being of her child, a character much like...Although reviewers of Tremblay＇s play For the Pleasure of Seeing Her Again （1998） focus on the monologues of the angry mother who rants about everyday concerns for the well-being of her child, a character much like the one who initiated Tremblay＇s career （the old song）, the author will focus on how the narrator＇s memory of his mother stage by stage in his life enacted before our eyes, permits Tremblay to self-consciously explain that his artistry reaches far beyond bringing the people he knew best in his youth, who had no knowledge of theater history, acting, and directing and staging, to the stage. His growth as an artist and his ＂new songs＂ are a result of his own continuous development of that knowledge展开更多
Graphene oxide(GO) has been demonstrated to be an effective hydrophilic nanofiller to modify the polymeric membranes when forming a mixed matrix structure. GO quantum dots(QDs) are promising candidates to fully exert ...Graphene oxide(GO) has been demonstrated to be an effective hydrophilic nanofiller to modify the polymeric membranes when forming a mixed matrix structure. GO quantum dots(QDs) are promising candidates to fully exert the rich oxygen containing functional groups due to their unique size induced edge effects. In this work, GO QDs modified polysulfone(PSF) ultrafiltration(UF) membranes were prepared by phase inversion method with various GO QDs loadings(0.1–0.5 wt.%). A proper amount of GO QDs addition led to a more porous and hydrophilic membrane structure. With 0.3 wt.% GO QDs, the membranes showed a60% increase in permeability(130.54 vs. 82.52 LMH bar^-1).The pristine PSF membranes had a complete cutoff of bovine serum albumin molecules and it was well maintained with GO QDs incorporated. The membranes with 0.5 wt.% GO QDs exhibited the highest flux recovery ratio of 89.7% and the lowest irreversible fouling of 10.3%(54.5% and 33.3% for the pristine PSF membranes). Our results proved that GO QDs can function as effective nanofillers to enhance the hydrophilicity, permeability and antifouling performance of PSF UF membranes.展开更多
文摘Objectives:This study aimed to identify facilitators and barriers to parent-child communication in pediatric palliative care,providing insights for medical professionals developing targeted interventions to enhance parent-child communication and improve its effectiveness.Methods:Whittemore and Knafl’s integrative review method was employed to guide a systematic search for literature in six databases(Medline,Embase,CINAHL Complete,PsycINFO,Web of Science,and Cochrane Library).Peer-reviewer articles published in the English language from inception to December 2023.All of the identified studies were screened,extracted,and analyzed independently by two researchers.Results:Twenty-four articles were included.Thefindings of the relevant studies were analyzed using thematic analysis.Four themes were identified as facilitators:legacy-making,resilience training programs,guidance from the healthcare team,and positive communication.Seven themes were identified as barriers:denial,being unprepared and evasive,mutual protection,being overwhelmed by painful emotions and overloaded with information,incorrect views of medical professionals and parents,negative communication,and cultural context.Conclusions:Parents and professionals should avoid myths about protecting the child and encourage open communication that respects the child’s wishes.The specialized pediatric palliative care team should carefully monitor parent-child communication,determine if any obstacles exist,and design more interventions to enhance it.
文摘Objective The entorhino-hippocampal pathway is the major excitatory input from neurons of the entorhinal cortex on both ipsilateral and contralateral hippocampus/dentate gyrus. This fiber tract consists of the alvear path, the perforant path and a crossed commissural projection. In this study, the histogenesis and development of the various subsets of the entorhino-hippocampal projection have been investigated. Methods Dil, DiO and fast blue tracing as well as anti-calretinin immunocytochemistry were carried out with prenatal and postnatal rats at different ages. Results The alvear path and the commissural pathway started to develop as early as embryonic day （E） 16, while the first perforant afferents reached the stratum lacunosum-moleculare of the hippocampus at E 17 and the outer molecular layer of dentate gyrus at postnatal day （P） 2, respectively. Retrograde tracing with DiI identified entorhinal neurons in layer II to IV as the origin of entorhino-hippocampal pathway. Furthermore, anti-calretinin immunocytochemistry revealed transitory Cajal- Retzius （CR） cells in the stratum lacunosum-moleculare of the hippocampus from as early as E 16. DiI labeling of entorhinal cortex fibers and combined calretinin-immunocytochemistry showed a close association between CR cells and entorhinal afferents. Conclusion The subsets of entorhino-hippocampal pathway appear in the developmental hippocampus during El6 - P2. The temporal and spatial relationship between CR cell and perforant afferent suggests the role of this cell type as a guiding cue for entorhinal afferents at early cortical development.
基金Supported by Applied and Basic Research Plan of Nantong City,Jiangsu Province(MS12015074)~~
文摘The differences in growth period and seeding to heading duration of both parents of Tongyoujing 1 are 4-6 and 3-5 d, respectively. Plant height of the male parent was 6-8 cm higher than that of the female parent, and blooming time of the male parent was 30-60 min earlier than that of the female parent. The seed pro-duction technology points of Tongyoujing 1 include appropriate seeding （the differ-ence in sowing period of both parents is 3-5 d）, timely transplanting, reasonable layout （ratio of rows between both parents is 2：（6-8））, strengthening variety isolation, scientific fertilizer and water management （high fertilization for male parent and ade-quate fertilization for female parent）, reasonably regulating flowering period （to pro-mote flower synchronization）, artificial pollination （to improve outcrossing rate）, paying attention to miscel aneous plant removal and pest control and timely harvest.
文摘Although reviewers of Tremblay＇s play For the Pleasure of Seeing Her Again （1998） focus on the monologues of the angry mother who rants about everyday concerns for the well-being of her child, a character much like the one who initiated Tremblay＇s career （the old song）, the author will focus on how the narrator＇s memory of his mother stage by stage in his life enacted before our eyes, permits Tremblay to self-consciously explain that his artistry reaches far beyond bringing the people he knew best in his youth, who had no knowledge of theater history, acting, and directing and staging, to the stage. His growth as an artist and his ＂new songs＂ are a result of his own continuous development of that knowledge
基金supported by Beijing Natural Science Foundation(2172027)
文摘Graphene oxide(GO) has been demonstrated to be an effective hydrophilic nanofiller to modify the polymeric membranes when forming a mixed matrix structure. GO quantum dots(QDs) are promising candidates to fully exert the rich oxygen containing functional groups due to their unique size induced edge effects. In this work, GO QDs modified polysulfone(PSF) ultrafiltration(UF) membranes were prepared by phase inversion method with various GO QDs loadings(0.1–0.5 wt.%). A proper amount of GO QDs addition led to a more porous and hydrophilic membrane structure. With 0.3 wt.% GO QDs, the membranes showed a60% increase in permeability(130.54 vs. 82.52 LMH bar^-1).The pristine PSF membranes had a complete cutoff of bovine serum albumin molecules and it was well maintained with GO QDs incorporated. The membranes with 0.5 wt.% GO QDs exhibited the highest flux recovery ratio of 89.7% and the lowest irreversible fouling of 10.3%(54.5% and 33.3% for the pristine PSF membranes). Our results proved that GO QDs can function as effective nanofillers to enhance the hydrophilicity, permeability and antifouling performance of PSF UF membranes.
