Upon flaws of current blockchain platforms of heavyweight, large capacity of ledger, and time-consuming of synchronization of data, in this paper, we proposed a new paradigm of master-slave blockchain scheme(MSB) for ...Upon flaws of current blockchain platforms of heavyweight, large capacity of ledger, and time-consuming of synchronization of data, in this paper, we proposed a new paradigm of master-slave blockchain scheme(MSB) for pervasive computing that suitable for general PC, mobile device such as smart phones or PADs to participants in the working of mining and verification, in which we separated traditional blockchain model in 2 layer defined as master node layer and a series of slavery agents layer, then we proposed 2 approaches for partially computing model(PCM) and non-computing of model(NCM) in the MSB blockchain, Finally large amounts of simulations manifest the proposed master-slave blockchain scheme is feasible, extendible and suitable for pervasive computing especially in the 5 G generation environment, and can apply in the DRM-related applications.展开更多
AIM: To determine serum leptin levels and investigate their correlations with anthropometric and metabolic parameters and biochemical liver function in patients with chronic hepatitis C virus (HCV) infection and their...AIM: To determine serum leptin levels and investigate their correlations with anthropometric and metabolic parameters and biochemical liver function in patients with chronic hepatitis C virus (HCV) infection and their potential clinical implications.METHODS: Forty-two chronic HCV-infected patients without anti-viral treatment were enrolled in this study, 30 patients had chronic hepatitis C, 10 had cirrhosis, and 2 had hepatocellular carcinoma (HCC). Thirty age- and sex-matched healthy individuals served as controls. Serum leptin levels were determined by ELISA. The biochemical liver function and serum lipids were determined at the same time. The height and body weight of patients and controls were measured, and body mass index (BMI) and body fat were calculated simultaneously. The correlations of serum leptin levels with anthropometric and metabolic parameters and biochemical liver function were assessed statistically.RESULTS: The mean of serum leptin levels in patients with chronic hepatitis C, HCV-associated cirrhosis, HCVassociated HCC and control groups was (6.13±3.94),(5.25±4.21), (4.17±0.28), and (3.59±3.44) ng/mL, respectively. The serum leptin level in patients with chronic hepatitis C was significantly higher than that in controls. The serum leptin levels between cirrhotic patients and controls and between male and female cirrhotic patients had no significant difference. Serum leptin levels were positively-correlated with body fat, BMI, and apolipoprotein B (Apo B) in patients with chronic HCV infection. The serum alanine aminotransferase (ALT) levels were closelycorrelated with BMI in patients with chronic hepatitis C. CONCLUSION: HCV infection interferes with fat and lipid metabolism in patients with chronic HCV infection and leptin may play a role in hepatosteatosis.展开更多
Objectives Partial hepatectomy induces a rapid transformation within the remnant liver, prompting a wave of hepatocyte mitosis which abates when the lost cell mass has been recovered. The mechanism of co-ordinated con...Objectives Partial hepatectomy induces a rapid transformation within the remnant liver, prompting a wave of hepatocyte mitosis which abates when the lost cell mass has been recovered. The mechanism of co-ordinated control of metabolism and maintenance of function during this period of dynamic change is incompletely understood. Furthermore, the biochemical basis of growth regulation in the regenerating liver has not been well defined. We have studied human liver regeneration using in vivo 31-phosphorus magnetic resonance spectroscopy (31 P MRS). This non-invasive technique allows assay of high-energy phosphate compounds and also of phospholipid metabolites thought to be involved in cellular renewal processes.Methods Five patients undergoing liver resection were studied. Hepatic metabolism was evaluated using 31P MRS before surgery and on postoperative days 2,4,6 and 14. Estimation of liver volume by magnetic resonance imaging and blood sampling for biochemistry were performed at the same time points.Results We found that the regenerative response following loss of liver parenchyma produced a reversible decline in energy state which necessitated compensatory adjustments in liver synthetic and excretory (unctions. Volume regain was associated with alterations in phospholipid metabolism, which normalized when the hepatic growth spurt was completed.Conclusion These observations indicate that modulation of hepatocyte energy economy is necessary for the integrated recovery of liver cell mass and function. We propose that deficient hepatic energy production may explain the mechanism of liver failure after hepatectomy, and suggest that in vivo measurement of liver metabolism may provide a rational basis for the development and evaluation of hepatic support strategies.展开更多
The cave-site of Gruta da Furninha is a coastal karstic cavity. In the late 19th century, excavation of the sedimentary infill of the cave allowed the identification of two lithostratigraphic units: a Holocene one do...The cave-site of Gruta da Furninha is a coastal karstic cavity. In the late 19th century, excavation of the sedimentary infill of the cave allowed the identification of two lithostratigraphic units: a Holocene one dominated by sands, containing human bones and a Neolithic industry; and a Late Pleistocene one, containing a diverse set of fossils set and Paleolithic artifacts. This study mainly focuses on taphonomic and palaeoenvironmental data concerning the Pleistocene bird bones that were collected from six layers (at 11 m and 6.7 m asl). A main result of this study was the discovery of a left humerus fragment, with osteological features of the Alcidae family; from comparison with upper arms of distinct species of this family, it was concluded that this fossil belongs to Penguin impennis. The Pleistocene birds of the Furninha cave were also compared with the avifauna that currently occurs in the region of Peniche peninsula and a climate and environmental interpretation of the Pleistocene fossiliferous set is provided.展开更多
The article seeks to elucidate the status of transcendence in the historiography of secularization through the perspective of collective memory. It discusses two typological models dealing with the basic metaphysical ...The article seeks to elucidate the status of transcendence in the historiography of secularization through the perspective of collective memory. It discusses two typological models dealing with the basic metaphysical problem concerned with the presence and meaning of transcendence in real human existence. According to the first, the historical reality of secularization causes a break from the collective memory whose roots are in religion. In contrast, the second model considers that despite the deep transformations in the status of religion in a reality of secularization, an experience of historical continuity may also occur there. These models denote the two poles in the argument about the meaning and value of history for modem people. The article suggests a phenomenological analysis of the two models and criticizes their deficiencies. Finally, the "tension model" is outlined as a third alternative that aims at overcoming the binary situation created by the first two in favor of a perspective that necessitates and contains both immanence and transcendence.展开更多
Many Chinese people leave big cities for family reunions during the Chinese New Year (CNY), which is the most important public holiday in China. However, how modem mass human migration during the CNY holiday affects...Many Chinese people leave big cities for family reunions during the Chinese New Year (CNY), which is the most important public holiday in China. However, how modem mass human migration during the CNY holiday affects the urban heat island (UHI) is still un- known. Here, the authors investigate the role of modem human migration for the UHI effects during the CNY holiday for the period of 1992-2006 in Harbin City, Northeast China. The results show that during the CNY week, the UHI effects expressed as daily mean, maxi- mum, and minimum temperature differences between urban and rural stations averaged over the period of 1992-2006 are 0.65℃ (43%), 0.31℃ (48%), and 1.14℃ (71%) lower than during the background period (four weeks before and four weeks after the CNY week), re- spectively. Our findings identify previously unknown impacts of modem mass human migration on the UHI effects based on a case study in Harbin City.展开更多
Since the reform and opening up, people' s congress system has gone through four stages of development, is to restore respectively, the initial development, further strengthen and improve, deepen the development stag...Since the reform and opening up, people' s congress system has gone through four stages of development, is to restore respectively, the initial development, further strengthen and improve, deepen the development stage. From four stages of development, we can draw the four laws since the reform and opening up people' s congress system changes that adhere to the party' s leadership, adapt to changes in the economic system, in theory and in practice, innovation in the legal, institutional design and constantly improve the standard. Four stages and the four laws draw people' s congress system experiences, the study of people' s congress system in future developments of great significance.展开更多
Liver is a primary site of ethanol metabolism, which makes this organ susceptible to alcohol-induced damage. Alcoholic liver disease (ALD) has many manifestations and complicated pathogenesis. In this Topic Highligh...Liver is a primary site of ethanol metabolism, which makes this organ susceptible to alcohol-induced damage. Alcoholic liver disease (ALD) has many manifestations and complicated pathogenesis. In this Topic Highlight, we included the key reviews that characterize new findings about the mechanisms of ALD development and might be of strong interest for clinicians and researchers involved in liver alcohol studies.展开更多
Field experiments were conducted to study the inheritance of boron efficiency in oilseed rape (Brassica napus L.) by evaluating the boron (B) efficiency coefficient (BEC, the ratio of the seed yield at below the criti...Field experiments were conducted to study the inheritance of boron efficiency in oilseed rape (Brassica napus L.) by evaluating the boron (B) efficiency coefficient (BEC, the ratio of the seed yield at below the critical boron level to that at the boron-sufficient level) with 657 F2:3 lines of a population derived from a cross between a B-efficient cultivar, Qingyou 10, and a B-inefficient cultivar, Bakow. Qingyou 10 had high BEC as well as high seed yield at low available soil B. On the contrary, Bakow produced low seed yield at low B status. Boron deficiency decreased the seed yield of the F2:3 lines to different extents and the distribution of BEC of the population showed a bimodal pattern. When the 657 F2:3 lines were grouped into B-efficient lines and B-inefficient lines according to their BEC, the ratio of B-efficient lines to B-inefficient lines fitted the expected ratio (3:1), indicating that one major gene controlled the B-efficiency trait. 127 F2:3 lines selected from the population at random, with distribution of BEC similar to that of the overall population, were used to identify the target region for fine mapping of the boron efficiency gene.展开更多
This thesis makes an analysis of the influence of the implementation of university personnel agency on three participators of universities, agency, and agency personnel. It is pointed out those personnel agency of the...This thesis makes an analysis of the influence of the implementation of university personnel agency on three participators of universities, agency, and agency personnel. It is pointed out those personnel agency of the current period is mainly transforming fi'om "personnel relations agency" to "household register relation affiliation" in terms of initial system design intention. Finally, it proposes that we should further improve the existing university personnel agency system, so as to eliminate the adverse effects on all parties.展开更多
Representing the fundamental eore of China's political fabric, the system of people's congresses ensures that the people are the mas- ters of the country. State power is exercised by the people through the Nat...Representing the fundamental eore of China's political fabric, the system of people's congresses ensures that the people are the mas- ters of the country. State power is exercised by the people through the National People's Congress (NPC) and local people's congresses. The preeminence of the NPC as the highest organ of state power is enshrined in China's Constitution. Heads of exeeutive, judicial and procuratorial organs are elected or appointed by people's congress- es, responsible to them and subject to their oversight. The decision- making on major public affairs is within the purview of people's congresses. The executive branch is responsible for implementing the laws, resolutions and decisions adopted by people's congresses.展开更多
Political development under socialism with Chinese character- istics has evolved over time as the Chinese people made sustained efforts to build a better society under the leadership of the CPC by integrating the basi...Political development under socialism with Chinese character- istics has evolved over time as the Chinese people made sustained efforts to build a better society under the leadership of the CPC by integrating the basic tenets of Marxism with China's specific conditions. The key features of such a process comprise leader- ship by the CPC, ownership by the people, and the rule of law. It is informed by continued efforts to improve the system of people's congresses, multiparty eooperation and political consultation under the leadership of the CPC, regional ethnic autonomy and community-level self-governance. Its objective is to continuously improve and develop the socialist political system.展开更多
基金supported by the National Natural Science Foundation of China under Grant 61272519the Research Funds of Blockchain Joint Lab between BUPT and BCTthe joint Blockchain and Security Lab between BUPT and CAPSTONE
文摘Upon flaws of current blockchain platforms of heavyweight, large capacity of ledger, and time-consuming of synchronization of data, in this paper, we proposed a new paradigm of master-slave blockchain scheme(MSB) for pervasive computing that suitable for general PC, mobile device such as smart phones or PADs to participants in the working of mining and verification, in which we separated traditional blockchain model in 2 layer defined as master node layer and a series of slavery agents layer, then we proposed 2 approaches for partially computing model(PCM) and non-computing of model(NCM) in the MSB blockchain, Finally large amounts of simulations manifest the proposed master-slave blockchain scheme is feasible, extendible and suitable for pervasive computing especially in the 5 G generation environment, and can apply in the DRM-related applications.
基金Supported by the National Natural Science Foundation of China, No. 30170842
文摘AIM: To determine serum leptin levels and investigate their correlations with anthropometric and metabolic parameters and biochemical liver function in patients with chronic hepatitis C virus (HCV) infection and their potential clinical implications.METHODS: Forty-two chronic HCV-infected patients without anti-viral treatment were enrolled in this study, 30 patients had chronic hepatitis C, 10 had cirrhosis, and 2 had hepatocellular carcinoma (HCC). Thirty age- and sex-matched healthy individuals served as controls. Serum leptin levels were determined by ELISA. The biochemical liver function and serum lipids were determined at the same time. The height and body weight of patients and controls were measured, and body mass index (BMI) and body fat were calculated simultaneously. The correlations of serum leptin levels with anthropometric and metabolic parameters and biochemical liver function were assessed statistically.RESULTS: The mean of serum leptin levels in patients with chronic hepatitis C, HCV-associated cirrhosis, HCVassociated HCC and control groups was (6.13±3.94),(5.25±4.21), (4.17±0.28), and (3.59±3.44) ng/mL, respectively. The serum leptin level in patients with chronic hepatitis C was significantly higher than that in controls. The serum leptin levels between cirrhotic patients and controls and between male and female cirrhotic patients had no significant difference. Serum leptin levels were positively-correlated with body fat, BMI, and apolipoprotein B (Apo B) in patients with chronic HCV infection. The serum alanine aminotransferase (ALT) levels were closelycorrelated with BMI in patients with chronic hepatitis C. CONCLUSION: HCV infection interferes with fat and lipid metabolism in patients with chronic HCV infection and leptin may play a role in hepatosteatosis.
文摘Objectives Partial hepatectomy induces a rapid transformation within the remnant liver, prompting a wave of hepatocyte mitosis which abates when the lost cell mass has been recovered. The mechanism of co-ordinated control of metabolism and maintenance of function during this period of dynamic change is incompletely understood. Furthermore, the biochemical basis of growth regulation in the regenerating liver has not been well defined. We have studied human liver regeneration using in vivo 31-phosphorus magnetic resonance spectroscopy (31 P MRS). This non-invasive technique allows assay of high-energy phosphate compounds and also of phospholipid metabolites thought to be involved in cellular renewal processes.Methods Five patients undergoing liver resection were studied. Hepatic metabolism was evaluated using 31P MRS before surgery and on postoperative days 2,4,6 and 14. Estimation of liver volume by magnetic resonance imaging and blood sampling for biochemistry were performed at the same time points.Results We found that the regenerative response following loss of liver parenchyma produced a reversible decline in energy state which necessitated compensatory adjustments in liver synthetic and excretory (unctions. Volume regain was associated with alterations in phospholipid metabolism, which normalized when the hepatic growth spurt was completed.Conclusion These observations indicate that modulation of hepatocyte energy economy is necessary for the integrated recovery of liver cell mass and function. We propose that deficient hepatic energy production may explain the mechanism of liver failure after hepatectomy, and suggest that in vivo measurement of liver metabolism may provide a rational basis for the development and evaluation of hepatic support strategies.
文摘The cave-site of Gruta da Furninha is a coastal karstic cavity. In the late 19th century, excavation of the sedimentary infill of the cave allowed the identification of two lithostratigraphic units: a Holocene one dominated by sands, containing human bones and a Neolithic industry; and a Late Pleistocene one, containing a diverse set of fossils set and Paleolithic artifacts. This study mainly focuses on taphonomic and palaeoenvironmental data concerning the Pleistocene bird bones that were collected from six layers (at 11 m and 6.7 m asl). A main result of this study was the discovery of a left humerus fragment, with osteological features of the Alcidae family; from comparison with upper arms of distinct species of this family, it was concluded that this fossil belongs to Penguin impennis. The Pleistocene birds of the Furninha cave were also compared with the avifauna that currently occurs in the region of Peniche peninsula and a climate and environmental interpretation of the Pleistocene fossiliferous set is provided.
文摘The article seeks to elucidate the status of transcendence in the historiography of secularization through the perspective of collective memory. It discusses two typological models dealing with the basic metaphysical problem concerned with the presence and meaning of transcendence in real human existence. According to the first, the historical reality of secularization causes a break from the collective memory whose roots are in religion. In contrast, the second model considers that despite the deep transformations in the status of religion in a reality of secularization, an experience of historical continuity may also occur there. These models denote the two poles in the argument about the meaning and value of history for modem people. The article suggests a phenomenological analysis of the two models and criticizes their deficiencies. Finally, the "tension model" is outlined as a third alternative that aims at overcoming the binary situation created by the first two in favor of a perspective that necessitates and contains both immanence and transcendence.
基金supported by the National Natural Science Foundation of China(Grant Nos.41275089 and 41305071)the National Basic Research Program of China(Grant No.2012CB955604)Jingyong ZHANG was supported by the Jiangsu Collaborative Innovation Center for Climate Change
文摘Many Chinese people leave big cities for family reunions during the Chinese New Year (CNY), which is the most important public holiday in China. However, how modem mass human migration during the CNY holiday affects the urban heat island (UHI) is still un- known. Here, the authors investigate the role of modem human migration for the UHI effects during the CNY holiday for the period of 1992-2006 in Harbin City, Northeast China. The results show that during the CNY week, the UHI effects expressed as daily mean, maxi- mum, and minimum temperature differences between urban and rural stations averaged over the period of 1992-2006 are 0.65℃ (43%), 0.31℃ (48%), and 1.14℃ (71%) lower than during the background period (four weeks before and four weeks after the CNY week), re- spectively. Our findings identify previously unknown impacts of modem mass human migration on the UHI effects based on a case study in Harbin City.
文摘Since the reform and opening up, people' s congress system has gone through four stages of development, is to restore respectively, the initial development, further strengthen and improve, deepen the development stage. From four stages of development, we can draw the four laws since the reform and opening up people' s congress system changes that adhere to the party' s leadership, adapt to changes in the economic system, in theory and in practice, innovation in the legal, institutional design and constantly improve the standard. Four stages and the four laws draw people' s congress system experiences, the study of people' s congress system in future developments of great significance.
文摘Liver is a primary site of ethanol metabolism, which makes this organ susceptible to alcohol-induced damage. Alcoholic liver disease (ALD) has many manifestations and complicated pathogenesis. In this Topic Highlight, we included the key reviews that characterize new findings about the mechanisms of ALD development and might be of strong interest for clinicians and researchers involved in liver alcohol studies.
基金Project supported by the National Natural Science Foundation of China (No.30170549) the National High Tech-nology Research and Development Program (863 Program) of China (No.2004AA222190).
文摘Field experiments were conducted to study the inheritance of boron efficiency in oilseed rape (Brassica napus L.) by evaluating the boron (B) efficiency coefficient (BEC, the ratio of the seed yield at below the critical boron level to that at the boron-sufficient level) with 657 F2:3 lines of a population derived from a cross between a B-efficient cultivar, Qingyou 10, and a B-inefficient cultivar, Bakow. Qingyou 10 had high BEC as well as high seed yield at low available soil B. On the contrary, Bakow produced low seed yield at low B status. Boron deficiency decreased the seed yield of the F2:3 lines to different extents and the distribution of BEC of the population showed a bimodal pattern. When the 657 F2:3 lines were grouped into B-efficient lines and B-inefficient lines according to their BEC, the ratio of B-efficient lines to B-inefficient lines fitted the expected ratio (3:1), indicating that one major gene controlled the B-efficiency trait. 127 F2:3 lines selected from the population at random, with distribution of BEC similar to that of the overall population, were used to identify the target region for fine mapping of the boron efficiency gene.
文摘This thesis makes an analysis of the influence of the implementation of university personnel agency on three participators of universities, agency, and agency personnel. It is pointed out those personnel agency of the current period is mainly transforming fi'om "personnel relations agency" to "household register relation affiliation" in terms of initial system design intention. Finally, it proposes that we should further improve the existing university personnel agency system, so as to eliminate the adverse effects on all parties.
文摘Representing the fundamental eore of China's political fabric, the system of people's congresses ensures that the people are the mas- ters of the country. State power is exercised by the people through the National People's Congress (NPC) and local people's congresses. The preeminence of the NPC as the highest organ of state power is enshrined in China's Constitution. Heads of exeeutive, judicial and procuratorial organs are elected or appointed by people's congress- es, responsible to them and subject to their oversight. The decision- making on major public affairs is within the purview of people's congresses. The executive branch is responsible for implementing the laws, resolutions and decisions adopted by people's congresses.
文摘Political development under socialism with Chinese character- istics has evolved over time as the Chinese people made sustained efforts to build a better society under the leadership of the CPC by integrating the basic tenets of Marxism with China's specific conditions. The key features of such a process comprise leader- ship by the CPC, ownership by the people, and the rule of law. It is informed by continued efforts to improve the system of people's congresses, multiparty eooperation and political consultation under the leadership of the CPC, regional ethnic autonomy and community-level self-governance. Its objective is to continuously improve and develop the socialist political system.