In recent years,the assessment of proprioceptive function has received increased attention in clinical and motor skill research.This is not surprising given the growing body of scientific evidence on the importance of...In recent years,the assessment of proprioceptive function has received increased attention in clinical and motor skill research.This is not surprising given the growing body of scientific evidence on the importance of proprioceptive information for controlling nearly all facets of human movement;from standing to performing highly skilled movement patterns展开更多
Strategies to fill the huge gap in supply versus demand of human organs include bioartificial organs, growing humanized organs in animals, cell therapy, and implantable bioengineered constructs. Reproducing the comple...Strategies to fill the huge gap in supply versus demand of human organs include bioartificial organs, growing humanized organs in animals, cell therapy, and implantable bioengineered constructs. Reproducing the complex relations between different cell types, generation of adequate vasculature, and immunological complications are road blocks in generation of bioengineered organs, while immunological complications limit the use of humanized organs produced in animals. Recent developments in induced pluripotent stem cell (iPSC) biology offer a possibility of generating human, patient-specific organs in non-human primates (NHP) using patient-derived iPSC and NHP-derived iPSC lacking the critical developmental genes for the organ of interest complementing a NHP tetraploid embryo. The organ derived in this way will have the same human leukocyte antigen (HLA) profile as the patient. This approach can be curative in genetic disorders as this offers the possibility of gene manipulation and correction of the patient's genome at the iPSC stage before tetraploid complementation. The process of generation of patient-specific organs such as the liver in this way has the great advantage of making use of the natural signaling cascades in the natural milieu probably resulting in organs of great quality for transplantation. However, the inexorable scientific developments in this direction involve several social issues and hence we need to educate and prepare society in advance to accept the revolutionary consequences, good, bad and ugly.展开更多
Traditional biomechanical analyses of human movement are generally derived from linear mathematics.While these methods can be useful in many situations,they do not describe behaviors in human systems that are predomin...Traditional biomechanical analyses of human movement are generally derived from linear mathematics.While these methods can be useful in many situations,they do not describe behaviors in human systems that are predominately nonlinear.For this reason,nonlinear analysis methods based on a dynamical systems approach have become more prevalent in recent literature.These analysis techniques have provided new insights into how systems(1) maintain pattern stability,(2) transition into new states,and(3) are governed by short-and long-term(fractal) correlational processes at different spatio-temporal scales.These different aspects of system dynamics are typically investigated using concepts related to variability,stability,complexity,and adaptability.The purpose of this paper is to compare and contrast these different concepts and demonstrate that,although related,these terms represent fundamentally different aspects of system dynamics.In particular,we argue that variability should not uniformly be equated with stability or complexity of movement.In addition,current dynamic stability measures based on nonlinear analysis methods(such as the finite maximal Lyapunov exponent) can reveal local instabilities in movement dynamics,but the degree to which these local instabilities relate to global postural and gait stability and the ability to resist external perturbations remains to be explored.Finally,systematic studies are needed to relate observed reductions in complexity with aging and disease to the adaptive capabilities of the movement system and how complexity changes as a function of different task constraints.展开更多
In order to deal with partical occlusion, a semantic interaction based moving human tracking approach is put forward. Firstly human is modeled as moving blobs which are described as blob descriptions. Then moving blob...In order to deal with partical occlusion, a semantic interaction based moving human tracking approach is put forward. Firstly human is modeled as moving blobs which are described as blob descriptions. Then moving blobs are updated and verified by projecting these descriptions. The approach exploits improved fast gauss transform and chooses source and target samples to reduce compute cost. Multi-moving human can be tracked simply and part occlusion can be done well.展开更多
Background：Little is known about change in physical activity（PA） and its relationship to all-cause mortality among old people.There is even less information about the association between PA,fitness and all-cause mo...Background：Little is known about change in physical activity（PA） and its relationship to all-cause mortality among old people.There is even less information about the association between PA,fitness and all-cause mortality among people aged 80 years and above.The objective is to investigate persistence and change in PA over 5 years as a predictor of all-cause mortality,and fitnes as a mediator of this association,among people aged 80 and 85 years at the beginning of an 18-year mortality follow-up period.Methods：Using Evergreen Project data（started in 1989）,4 study groups were formed according to self-reported changes in PA level,over a 5-year period（starting in 1989–1990 and ending in 1994–1995）：remained active（RA,control group）,changed to inactive（CI）,remained inactive（RI）,and changed to active（CA）.Mortality was followed up over the 18-year period（1994–2012）.Cox models with different covariates such as age,sex,use of alcohol,smoking,chronic diseases,and a 10 m walking test were used to analyze the association between change in PA level and mortality.Results：Compared to RA,those who decreased their PA level（CI） between baseline and follow-up had higher all-cause mortality（hazard ratio（HR=2.09;95%CI：1.63–2.69） when adjusted for age,gender,and chronic diseases.RI showed the highest all-cause mortality（HR = 2.16;95%CI：1.59–2.93）.In CA,when compared against RA,the risk of all-cause mortality was not statistically significan（HR=1.51;95%CI：0.95–2.38）.In comparison with RA,when walking speed over 10 m was added as a covariate,all-cause mortality risk was almost statistically significan only in CI（HR=1.37;95%CI：1.00–1.87）.Conclusion：Persistence and change in PA level was associated with mortality.This association was largely explained by fitnes status.Randomized controlled studies are needed to test whether maintaining or increasing PA level could lengthen the life of old people.展开更多
This paper designs a mechanical swing of placementing mobile phone, which is inspired by the mechanical watch automatic winding process. The use of the kinetic energy generated by human body motion drives the wheel sw...This paper designs a mechanical swing of placementing mobile phone, which is inspired by the mechanical watch automatic winding process. The use of the kinetic energy generated by human body motion drives the wheel swing and the generator, it can carry out mobile phone additional charge through the electronic components rectifier and DC/DC converter regulator, the use of human motion and light energy can extend a fixed charge mobile phone standby time. The human motion power uses electromagnetic coupling technique and collects energy by using foot swing, solar power generation uses DSP chip in TMS320F28927 control a plurality of charging circuit, inverter circuit and solar maximum power point tracking by sampling and multiple output PWM wave. Finally, charging process has the basic constant current process discovered by device testing, the design of human motion and light energy mobile phone charger can satisfy the need of mobile phone rechargeable lithium batteries.展开更多
In the process of China’s dynamic social changes over the past decades, the young-parent identity construction of an emerging middle class and the resulting changes of social-cultural values in this context have attr...In the process of China’s dynamic social changes over the past decades, the young-parent identity construction of an emerging middle class and the resulting changes of social-cultural values in this context have attracted the attention of academic research in recent years. With the focus on the discursive construction of parent identity, this study examines the utilization of first-person pronouns in three different interactional contexts, namely, parent-teacher interaction, parent-parent interaction, and parent-child interaction. The study further explores the patterns of alignment between the parents and their children, parents and teachers of their children, and peer parents during the process of identity construction, followed by a discussion of the implication that young, emerging middleclass Chinese parents fundamentally shape themselves as "concerned" and "involved" parents and the change of values between collectivity and agency. The study not only demonstrates the dynamic and pluralistic nature of parent identity but also deepens our understanding of the indexical roles of first-person pronouns in the discursive construction of emerging middle-class Chinese parent identity and its relationship with the recent social-cultural changes in the Chinese context.展开更多
基金supported by the Deutsche Forschungsgemeinschaft (No.KR 4595/1-1)
文摘In recent years,the assessment of proprioceptive function has received increased attention in clinical and motor skill research.This is not surprising given the growing body of scientific evidence on the importance of proprioceptive information for controlling nearly all facets of human movement;from standing to performing highly skilled movement patterns
文摘Strategies to fill the huge gap in supply versus demand of human organs include bioartificial organs, growing humanized organs in animals, cell therapy, and implantable bioengineered constructs. Reproducing the complex relations between different cell types, generation of adequate vasculature, and immunological complications are road blocks in generation of bioengineered organs, while immunological complications limit the use of humanized organs produced in animals. Recent developments in induced pluripotent stem cell (iPSC) biology offer a possibility of generating human, patient-specific organs in non-human primates (NHP) using patient-derived iPSC and NHP-derived iPSC lacking the critical developmental genes for the organ of interest complementing a NHP tetraploid embryo. The organ derived in this way will have the same human leukocyte antigen (HLA) profile as the patient. This approach can be curative in genetic disorders as this offers the possibility of gene manipulation and correction of the patient's genome at the iPSC stage before tetraploid complementation. The process of generation of patient-specific organs such as the liver in this way has the great advantage of making use of the natural signaling cascades in the natural milieu probably resulting in organs of great quality for transplantation. However, the inexorable scientific developments in this direction involve several social issues and hence we need to educate and prepare society in advance to accept the revolutionary consequences, good, bad and ugly.
文摘Traditional biomechanical analyses of human movement are generally derived from linear mathematics.While these methods can be useful in many situations,they do not describe behaviors in human systems that are predominately nonlinear.For this reason,nonlinear analysis methods based on a dynamical systems approach have become more prevalent in recent literature.These analysis techniques have provided new insights into how systems(1) maintain pattern stability,(2) transition into new states,and(3) are governed by short-and long-term(fractal) correlational processes at different spatio-temporal scales.These different aspects of system dynamics are typically investigated using concepts related to variability,stability,complexity,and adaptability.The purpose of this paper is to compare and contrast these different concepts and demonstrate that,although related,these terms represent fundamentally different aspects of system dynamics.In particular,we argue that variability should not uniformly be equated with stability or complexity of movement.In addition,current dynamic stability measures based on nonlinear analysis methods(such as the finite maximal Lyapunov exponent) can reveal local instabilities in movement dynamics,but the degree to which these local instabilities relate to global postural and gait stability and the ability to resist external perturbations remains to be explored.Finally,systematic studies are needed to relate observed reductions in complexity with aging and disease to the adaptive capabilities of the movement system and how complexity changes as a function of different task constraints.
文摘In order to deal with partical occlusion, a semantic interaction based moving human tracking approach is put forward. Firstly human is modeled as moving blobs which are described as blob descriptions. Then moving blobs are updated and verified by projecting these descriptions. The approach exploits improved fast gauss transform and chooses source and target samples to reduce compute cost. Multi-moving human can be tracked simply and part occlusion can be done well.
文摘Background：Little is known about change in physical activity（PA） and its relationship to all-cause mortality among old people.There is even less information about the association between PA,fitness and all-cause mortality among people aged 80 years and above.The objective is to investigate persistence and change in PA over 5 years as a predictor of all-cause mortality,and fitnes as a mediator of this association,among people aged 80 and 85 years at the beginning of an 18-year mortality follow-up period.Methods：Using Evergreen Project data（started in 1989）,4 study groups were formed according to self-reported changes in PA level,over a 5-year period（starting in 1989–1990 and ending in 1994–1995）：remained active（RA,control group）,changed to inactive（CI）,remained inactive（RI）,and changed to active（CA）.Mortality was followed up over the 18-year period（1994–2012）.Cox models with different covariates such as age,sex,use of alcohol,smoking,chronic diseases,and a 10 m walking test were used to analyze the association between change in PA level and mortality.Results：Compared to RA,those who decreased their PA level（CI） between baseline and follow-up had higher all-cause mortality（hazard ratio（HR=2.09;95%CI：1.63–2.69） when adjusted for age,gender,and chronic diseases.RI showed the highest all-cause mortality（HR = 2.16;95%CI：1.59–2.93）.In CA,when compared against RA,the risk of all-cause mortality was not statistically significan（HR=1.51;95%CI：0.95–2.38）.In comparison with RA,when walking speed over 10 m was added as a covariate,all-cause mortality risk was almost statistically significan only in CI（HR=1.37;95%CI：1.00–1.87）.Conclusion：Persistence and change in PA level was associated with mortality.This association was largely explained by fitnes status.Randomized controlled studies are needed to test whether maintaining or increasing PA level could lengthen the life of old people.
文摘This paper designs a mechanical swing of placementing mobile phone, which is inspired by the mechanical watch automatic winding process. The use of the kinetic energy generated by human body motion drives the wheel swing and the generator, it can carry out mobile phone additional charge through the electronic components rectifier and DC/DC converter regulator, the use of human motion and light energy can extend a fixed charge mobile phone standby time. The human motion power uses electromagnetic coupling technique and collects energy by using foot swing, solar power generation uses DSP chip in TMS320F28927 control a plurality of charging circuit, inverter circuit and solar maximum power point tracking by sampling and multiple output PWM wave. Finally, charging process has the basic constant current process discovered by device testing, the design of human motion and light energy mobile phone charger can satisfy the need of mobile phone rechargeable lithium batteries.
基金a part of the Chinese MOE Key Research Project of Humanities and Social Science (Project No.: 16JJD740006) conducted by the Centre for Linguistics and Applied Linguistics, Guangdong University of Foreign Studies
文摘In the process of China’s dynamic social changes over the past decades, the young-parent identity construction of an emerging middle class and the resulting changes of social-cultural values in this context have attracted the attention of academic research in recent years. With the focus on the discursive construction of parent identity, this study examines the utilization of first-person pronouns in three different interactional contexts, namely, parent-teacher interaction, parent-parent interaction, and parent-child interaction. The study further explores the patterns of alignment between the parents and their children, parents and teachers of their children, and peer parents during the process of identity construction, followed by a discussion of the implication that young, emerging middleclass Chinese parents fundamentally shape themselves as "concerned" and "involved" parents and the change of values between collectivity and agency. The study not only demonstrates the dynamic and pluralistic nature of parent identity but also deepens our understanding of the indexical roles of first-person pronouns in the discursive construction of emerging middle-class Chinese parent identity and its relationship with the recent social-cultural changes in the Chinese context.
