Skin care efficacy study of recombinant humanized collagen based on in vitro level

Studying the skin care efficacy of recombinant humanized collagen based on in vitro level.The stability of the recombinant humanized collagen was first analyzed by treating at different temperatures,then its skincare efficacy based on in vitro level was evaluated by detecting the inhibition rate of elastase,the inhibition rate of collagenase,the protein content of type I collagen in human fibroblasts,the inhibition of reactive oxygen species(ROS)with human keratinocytes,and the effects of the recombinant humanized collagen on the expression of hyaluronic acid(HA),filaggrin(FLG)and transglutaminase 1(TGM1)in keratinocytes.The results showed that recombinant humanized collagen was able to maintain stability at temperatures below 70℃.With regard to its skincare efficacy,recombinant humanized collagen could inhibit elastase and collagenase activities and promote the increase of type I collagen content in human fibroblasts.It also showed good inhibition of ROS in keratinocytes in vitro and could increase the expression of HA,FLG,and TGM1 in keratinocytes.In short,the recombinant humanized collagen exhibited a favourable skin care effect in vitro level.This study proved that it has potential firming,anti-wrinkle,moisturizing,and repairing efficacy,and is a valuable cosmetic raw material.

基于《黄帝内经》原文浅述针刺深浅之道

《黄帝内经》原文详细描述了针刺的深浅与人体形气、四时经气、脏腑血气、疾病性质紧密相关。针刺时选择恰当的深度可有效提高临床疗效。

Longitudinal Mechanical Properties of Small-Diameter Polyurethane Vascular Graft Reinforced by Tubular Knitted Fabric

The vascular graft with 4 mm diameter was prepared by casting one layer of polyurethane (PU) film onto the knitting tubular fabric as the reinforced support. The effects of different PU content and wall thickness on the longitudinal mechanical properties of vascular graft were investigated. The breaking elongation, breaking force, initial modulus and breaking work were studied. The results showed that the longitudinal mechanical properties of vascular graft were enhanced as the content of polyurethane increased, which resulted from the combination of PU excellent elasticity and fabric preferable strength.

Study on Body Form and Garment Size Series of the Middle Age and Aged People

This paper was designed to analyze on the data, which was obtained from 'National Physique Fitness Investigation Report (2000)'. In order to get the typical body form and figure type of the middle age and aged people, it was focused on the body form data of this group (age 40 - 60). After calculation and analyzing, the distinguishing feature of body form and the distribution of figure type were deduced. Finally, the re-classification of body form for Chinese middle age and aged people was suggested. It as also suggested that a new garment size series especially for the middle age and aged should be built to fit for these people. This conclusion would be useful and significant to design and production for clothing company, especially that who take the aged people as their target consumer.

CORAL AS A CARRIER FOR RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2

By combining coral with recombinant human bone morphogenetic protein-2 (rhBMP-2), rhBMP-2/coral composite was obtained in this study. Following implantation of the composite into the muscle pouches of mice, cartilage growth was induced in the pores or on the surface of the implants at one week, woven bone at three week and lamellar bone with bone marrow at six week, and coral was absorbed partially. The induced formation of endochondral bone was time-related and rhBMP-2 dose-related. The results of this study indicate that the composite possesses a superior ability of osteogenesis, and coral acts as one of the most suitable rhBMP-2 slowrelease carriers currently available. The composite will be a new type of bone substitute to be used in orthopaedics and maxillofacial surgery.

Body Fuzzy Pattern Recognition in Woman Basic Block Design

Basic block is the foundation of clothing construction design because it is the media between body and clothes and the fitness of clothes should be based on the accuracy of basic block. That needs us to recognize body not to record it. This paper reports the Algorithm of woman body fuzzy pattern recognition. It is organized in three sections:(i) extracting woman body feature; (ii) establishing membership functions of feature indexes;(iii) presenting an Algorithm for woman body fuzzy pattern recognition by example.

Formation of GaN Nanowires by Ammoniating Ga_2O_3 Films Deposited on Oxidized Al Layers on Si Substrate

Large quantities of gallium nitride(GaN) nanowires have been prepared via ammoniating the Ga2O3 films deposited on the oxidized aluminum layer at 950 ℃ in a quartz tube. The nanowires have been confirmed as crystalline wurtzite GaN by X-ray diffraction, X-ray photoelectron spectrometry scanning electron microscope and selected-area electron diffraction. Transmission electron microscope(TEM) and scanning electron microscopy(SEM) reveal that the nanowires are amorphous and irregular, with diameters ranging from 30 nm to 80 nm and lengths up to tens of microns. Selected-area electron diffraction indicates that the nanowire with the hexagonal wurtzite structure is the single crystalline. The growth mechanism is discussed briefly.

The Design of Desk Lamp on 3D Modeling based on Solidworks

This paper introduces the solidworks design flow, design methods and design principles of desk lamp. And we use the ergonomics principle, analysis the function of each part of the lamp, and analyses the design of lamp components, to meet user needs in the bedroom, do practical, human nature and convenient lamp. The application shows that the use of this software can make easier the realization of the design of the parts with complex shape, raise the design efficiency, optimize the product structure and save the cost.

Modus operandi of transnational transfer pricing for window dressing

A goal of transfer pricing may be to maximize after tax revenue by setting transfer prices that reduce the total tax paid. ＂Transfer pricing＂ is the pricing of products or services provided by one division to other division of the same corporate entity. Most of the corporate entities are using the method of ＂Window dressing＂, which is a technique used in preparation of financial statements of corporate entities. A transnational corporation is any enterprise that undertakes Foreign Direct Investment （FDI）, owns or controls income gathering assets in more than one country, produces goods or services outsides its country of origin, or engages in international production. Profitability of the transnational corporate entities is being manipulated by the technique of transfer pricing. Abuse of transfer prices is a key tool used by the corporate entities to think that they have virtually no profit; hence, they shouldn＇t pay any taxes. India needs to realize the fundamental need for co-operation among tax administrations in order to remove the obstacles that international double taxation presents to the free movement of goods, services and capital between various countries. In this context, one needs to consider that transactions among associated enterprises may take place under different conditions from those taking place among independent enterprises, while enforcing the act of transfer price mechanism. This paper focuses on transfer pricing and its implications in transnational transactions.

Office Furniture Design for Wheelchair User

There are an estimated 1.19 million wheelchair users in Spain. People use wheelchairs for a variety of reasons, the most common one is paralysis from spinal cord injuries. Current estimates indicate there are around 504,000 people alive in Spain with spinal cord injuries. Among other reasons for using wheelchairs are： fatigue from multiple sclerosis, muscle weakness from muscular dystrophy, lower limb spasticity from cerebral palsy, and missing limbs due to amputation. People who use wheelchairs may encounter a variety of obstacles at their workstations depending on their limitations. Some possible accommodations could be adjustable height desk or table for a person who cannot work comfortably at an existing desk, accessible filing system or office supplies, and frequently used materials on most accessible shelves or drawers for a person who cannot reach upper and lower shelves and drawers. This paper presents the graphical design of a workstation for wheelchair users, in this case, technical, anthropometric, ergonomic, aesthetics and scientists aspects have been analyzed. The design of composite structure conduct to explicit safety constraints applied to office furniture requirements kept continuously current and updated as part of innovation. Finally, results are showed in a three-dimensional model.

Analysis of Buddhist sculpture art in Wei, Jin, southern and Northern Dynasties

The emergence and development of Buddhist sculpture has completely changed the original Chinese ancient sculpture, rich China sculpture theme, greatly promote the development of the Chinese sculpture, in the Wei and Jin Dynasties, Buddhist sculpture received considerable development, the art form is abundant, representative of the ＂ slim but clear appearance＂ and＂ images of noble figures ＂two kinds of modeling features. From the perspective of historical background and aesthetic orientation, this paper analyzes and studies the overall features of the art of carving art in this historical period, as well as its profound influence on the development of Chinese Buddhist statues.

Morphological Deformities in the Wild Population of C. gariepinus in Ado-Ekiti, Nigeria

Clarias ganepinus from wild population, which was purchased from fish mongers in Ado-Ekiti, Nigeria, were examined for possible deformities in their body. Eighty individuals were collected. Various types of deformities observed were recorded and later photographed. The present study reported for the first time the occurrence of morphological deformities in C. gariepinus natural ecosystem in Ado-Ekiti, Nigeria. The rivers, where the fish were collected, were found to have been exposed to persistent human activities. The possible causes of the deformities may be pollution from human activities or other factors such as poor nutrition, heredity, diseases. The etiology of the deformities in Clarias under this condition is recommended to be studied in detail.

Recombinant human Flt3 ligand exerts both direct and indirect effects on hematopoiesis

OBJECTIVE: To investigate the direct effects of the Flt3 ligand (FL) on hematopoiesis, such as the stimulation of the formation of hematopoietic colonies and the proliferation of dendritic cells, as well as the indirect stimulation of hematopoiesis, especially via the proliferation of endothelial cells. METHODS: Mononuclear cells from human cord blood were plated in methylcellulose medium containing different cytokines to induce hematopoietic colony formation. Dendritic cells (DCs) were induced from the mononuclear cells with a cytokine cocktail with or without recombinant human soluble FL (rhFL; 100 ng/ml). The Flt3 receptors on the surface of a human microvascular endothelial cell line (ECV) were analyzed by flow cytometry. The proliferation of ECV stimulated by rhFL was measured with the microculture tetrazolium assay. The levels of FL, IL-6, IL-8, G-CSF and GM-CSF in the supernatant of ECV cultures were measured by enzyme linked immunoabsorbent assay (ELISA). RESULTS: rhFL stimulates colony formation from cord blood when used as a sole stimulant. FL in combination with other cytokines increased colony formation significantly. The number of DCs was approximately 2.5 times higher when rhFL was used. rhFL stimulates the proliferation of ECV on which Flt3 receptors are expressed. Furthermore, ECV secretes FL, IL-6, IL-8, G-CSF and GM-CSF, which were augmented by tumor necrosis factor-alpha and rhFL. CONCLUSIONS: rhFL enhances hematopoietic colony formation and DC proliferation from human cord blood cells. FL not only stimulates the proliferation of ECV, but is also secreted by ECV. FL may exert direct and indirect effects on hematopoiesis.

Style Notebook

01Linda Farrow x House Of Holland玩味无框眼镜〉怀旧眼镜潮流回归,令Linda Farrow成为大热品牌,近年她十分积极找不同时装设计单位合作,继早前Jeremy Scott、Matthew Williamson及Luella等合作企划成功后,2010年春夏季将会与Raf Simons及House Of Holland两位设计师推出全新合作系列。前者跟Linda Farrow合作无间,早有默契,至于初试啼声的Henry Holland,他的塑胶玻璃眼镜看似简约,然而配合橙、绿两款鲜艳颜色,却显现了Henry Holland一贯的玩味个性。眼镜于巴黎Colette率先发售,相信将会吸引不少年轻时装人。www.colette.

COMPLEX CONCEPT LATTICES FOR SIMULATING HUMAN PREDICTION IN SPORT

In order to address the study of complex systems,the detection of patterns in their dynamics could play a key role in understanding their evolution.In particular,global patterns are required to detect emergent concepts and trends,some of them of a qualitative nature.Formal concept analysis(FCA) is a theory whose goal is to discover and extract knowledge from qualitative data(organized in concept lattices).In complex environments,such as sport competitions,the large amount of information currently available turns concept lattices into complex networks.The authors analyze how to apply FCA reasoning in order to increase confidence in sports predictions by means of detecting regularities from data through the management of intuitive and natural attributes extracted from publicly available information.The complexity of concept lattices-considered as networks with complex topological structure- is analyzed.It is applied to building a knowledge based system for confidence-based reasoning,which simulates how humans tend to avoid the complexity of concept networks by means of bounded reasoning skills.

Experimental Observation of Two Phase Flow of R123 Inside a Herringbone Microfin Tube

Vapor-liquid two phase flow behavior of R123 inside herringbone microfin tubes has been studied. Herringbone microfin tube is a kind of internally finned tube in which microfins are installed inside the tube where the microfins form multi-V-shape in flow direction. For the present experiment three different types of herringbone microfin tubes with helix angle B = 8, 14 and 28 are used. Experimental observations showed how flow diverges and converges inside herringbone microfin tube due to fin arrangement. The effect is more remarkable for larger helix angle. From the measurements of the cross-sectional liquid flow rate distribution, the liquid removal and collection and the entrained droplet are discussed. Quantity of liquid droplets is increased with increase of helix angle. The tube with helix angle B = 28 shows higher quantity of liquid droplets than others.