通过现场采样及室内分析方法,对吉林省东部山区人参栽培基地土壤中有机氯农药残留和重金属污染现状进行了调查与评价。结果表明,拟建人参栽培基地土壤中重金属含量在背景值范围内,B H C、PC N B、D D T的含量分别为0.0004~0.1746、0.0...通过现场采样及室内分析方法,对吉林省东部山区人参栽培基地土壤中有机氯农药残留和重金属污染现状进行了调查与评价。结果表明,拟建人参栽培基地土壤中重金属含量在背景值范围内,B H C、PC N B、D D T的含量分别为0.0004~0.1746、0.0003~0.9378、0.0001~0.2058m g·kg-1、就污染的普遍性和严重性而言,PC N B污染最为普遍和严重。综合污染评价结果表明,敦化、抚松、集安3个观测地区的土壤环境质量等级小于2级,符合中药材G A P生产基地的要求。展开更多
The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological met...The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and mild conditions. For effectively extracting from the other panaxadiol saponins, the conversion process for ginsenoside C-K was investigated using snailases in this study. The univariate experimental design and response surface methodology were used to determine the optimal hydrolysis conditions for the conversion of ginsenoside Rbl into ginsenoside C-K by snailases. The optimum conditions were as follows: pH 5,12, temperature 51 ℃, ratio of snailase/substrate 0.21, and reaction time 48 h. On the basis of these parameters, the addition of 1.0 mmol· L- 1 ferric ion was found to significantly improve the enzymolysis ofsnailases for the first time. With the above conditions, the maximum conversion rate reached 89.7%, suggesting that the process can obviously increase the yield of ginsenoside C-K. The bioassay tests indicated that the ginsenoside C-K showed anti-tumor activity in a series of tumor cell lines. Based on these results, we can conclude that the process of rare ginsenoside C- K production by enzymolysis with snailase is feasible, efficient, and suitable for the industrial production and application.展开更多
Steelmaking–refining–Continuous Casting(SCC) scheduling is a worldwide problem, which is NP-hard. Effective SCC scheduling algorithms can help to enhance productivity, and thus make significant monetary savings. Thi...Steelmaking–refining–Continuous Casting(SCC) scheduling is a worldwide problem, which is NP-hard. Effective SCC scheduling algorithms can help to enhance productivity, and thus make significant monetary savings. This paper develops an Improved Artificial Bee Colony(IABC) algorithm for the SCC scheduling. In the proposed IABC, charge permutation is employed to represent the solutions. In the population initialization, several solutions with certain quality are produced by a heuristic while others are generated randomly. Two variable neighborhood search neighborhood operators are devised to generate new high-quality solutions for the employed bee and onlooker bee phases, respectively. Meanwhile, in order to enhance the exploitation ability, a control parameter is introduced to conduct the search of onlooker bee phase. Moreover, to enhance the exploration ability,the new generated solutions are accepted with a control acceptance criterion. In the scout bee phase, the solution corresponding to a scout bee is updated by performing three swap operators and three insert operators with equal probability. Computational comparisons against several recent algorithms and a state-of-the-art SCC scheduling algorithm have demonstrated the strength and superiority of the IABC.展开更多
This paper examines the transition of growth stage China is about to experience and the main conclusions are as follows: (1) Phase Ⅰ of economic growth driven by investment and export is losing the momentum of eff...This paper examines the transition of growth stage China is about to experience and the main conclusions are as follows: (1) Phase Ⅰ of economic growth driven by investment and export is losing the momentum of efficiency enhancement through intervention and the growth stage of efficiency enhancement through structural adjustment is coming to an end. Urbanization and the development of service sector will inaugurate Phase Ⅱ of stable economic growth characterized by structural optimization through efficiency enhancement; (2) Three leading factors promoting the transition from Phase Ⅰ to Phase Ⅱ include: demographic changes and the emergence of workforce turning point, the reversion of factor elasticity parameters of long-term growth function, and service-oriented economic structure; (3) Developed provinces and municipalities in east China have already entered into the channel of economic deceleration. With increasing urbanization rate, accelerating service-oriented structure and declining demographic dividend after 2016, China's economic slowdown would be inevitable if labor productivity fails to improve.展开更多
文摘通过现场采样及室内分析方法,对吉林省东部山区人参栽培基地土壤中有机氯农药残留和重金属污染现状进行了调查与评价。结果表明,拟建人参栽培基地土壤中重金属含量在背景值范围内,B H C、PC N B、D D T的含量分别为0.0004~0.1746、0.0003~0.9378、0.0001~0.2058m g·kg-1、就污染的普遍性和严重性而言,PC N B污染最为普遍和严重。综合污染评价结果表明,敦化、抚松、集安3个观测地区的土壤环境质量等级小于2级,符合中药材G A P生产基地的要求。
基金Supported by the National Natural Science Foundation of China(21476182,21776227,21776228)Shaanxi Key Laboratory of Degradable Biomedical Materials Program(2014SZS07-K04,2014SZS07-P05,15JS106,2014SZS07-Z01,2014SZS07-Z02,2016SZSj-35,2014SZS07-K03)Shaanxi R&D Center of Biomaterials and Fermentation Engineering Program(2015HBGC-04)
文摘The rare ginsenoside Compound K (C-K) is attracting more attention because of its good physiological activity and urgent need. There are many pathways to obtain ginsenoside C-K, including chemical and biological methods. Among these, the conversion of PPD-type ginsenosides by enzymatic hydrolysis is a trend due to its high efficiency and mild conditions. For effectively extracting from the other panaxadiol saponins, the conversion process for ginsenoside C-K was investigated using snailases in this study. The univariate experimental design and response surface methodology were used to determine the optimal hydrolysis conditions for the conversion of ginsenoside Rbl into ginsenoside C-K by snailases. The optimum conditions were as follows: pH 5,12, temperature 51 ℃, ratio of snailase/substrate 0.21, and reaction time 48 h. On the basis of these parameters, the addition of 1.0 mmol· L- 1 ferric ion was found to significantly improve the enzymolysis ofsnailases for the first time. With the above conditions, the maximum conversion rate reached 89.7%, suggesting that the process can obviously increase the yield of ginsenoside C-K. The bioassay tests indicated that the ginsenoside C-K showed anti-tumor activity in a series of tumor cell lines. Based on these results, we can conclude that the process of rare ginsenoside C- K production by enzymolysis with snailase is feasible, efficient, and suitable for the industrial production and application.
基金Supported by the National Natural Science Foundation of China(51705177,51575212)the Program for New Century Excellent Talents in University(NCET-13-0106)the Program for HUST Academic Frontier Youth Team
文摘Steelmaking–refining–Continuous Casting(SCC) scheduling is a worldwide problem, which is NP-hard. Effective SCC scheduling algorithms can help to enhance productivity, and thus make significant monetary savings. This paper develops an Improved Artificial Bee Colony(IABC) algorithm for the SCC scheduling. In the proposed IABC, charge permutation is employed to represent the solutions. In the population initialization, several solutions with certain quality are produced by a heuristic while others are generated randomly. Two variable neighborhood search neighborhood operators are devised to generate new high-quality solutions for the employed bee and onlooker bee phases, respectively. Meanwhile, in order to enhance the exploitation ability, a control parameter is introduced to conduct the search of onlooker bee phase. Moreover, to enhance the exploration ability,the new generated solutions are accepted with a control acceptance criterion. In the scout bee phase, the solution corresponding to a scout bee is updated by performing three swap operators and three insert operators with equal probability. Computational comparisons against several recent algorithms and a state-of-the-art SCC scheduling algorithm have demonstrated the strength and superiority of the IABC.
文摘This paper examines the transition of growth stage China is about to experience and the main conclusions are as follows: (1) Phase Ⅰ of economic growth driven by investment and export is losing the momentum of efficiency enhancement through intervention and the growth stage of efficiency enhancement through structural adjustment is coming to an end. Urbanization and the development of service sector will inaugurate Phase Ⅱ of stable economic growth characterized by structural optimization through efficiency enhancement; (2) Three leading factors promoting the transition from Phase Ⅰ to Phase Ⅱ include: demographic changes and the emergence of workforce turning point, the reversion of factor elasticity parameters of long-term growth function, and service-oriented economic structure; (3) Developed provinces and municipalities in east China have already entered into the channel of economic deceleration. With increasing urbanization rate, accelerating service-oriented structure and declining demographic dividend after 2016, China's economic slowdown would be inevitable if labor productivity fails to improve.