Objective: To explore the levels of serum and ascitic fluid soluble tumor necrosis factor receptor-p55 (sTNFR-p55) and understand their clinical implication in primary hepatocellular carcinoma (HCC) patients. Methods:...Objective: To explore the levels of serum and ascitic fluid soluble tumor necrosis factor receptor-p55 (sTNFR-p55) and understand their clinical implication in primary hepatocellular carcinoma (HCC) patients. Methods: Enzyme-linked immunosorbent assay (ELISA) was used to examine the levels of sTNFR-p55 in the serum and ascitic fluid in 25 HCC patients and 25 patients with liver cirrhosis (LC). The test was also performed on the serum of 30 healthy subjects who served as control group. To assess the clinical effects of increased serum concentrations of sTNFR-p55, four parameters were analyzed by logistic regression. Results: Serum and ascitic fluid levels of sTNFR-p55 in HCC patients were significantly higher than those in LC patients and controls (P=0. 001). No significant difference was found between serum sTNFR-p55 levels in the latter 2 groups (P = 0. 19), and positive correlation between serum levels of sTNFR-p55 and that in ascitic fluid was noted in the 2 patient groups (r=1. 000, P<0. 001). Levels of the sTNFR-p55 positively correlated with TBIL and AFP in the peripheral blood of HCC patients (r=0. 524, P = 0. 01 and r=0. 234, P = 0. 03, respectively). Conclusion: Increased levels of sTNFRs-p55 in the serum and ascitic fluid could reflect the abnormal immune status of the HCC patients and may help predict the development of the tumor.展开更多
The diversity of existing food may decrease malnutrition through the consumption of underutilized species. In Mexico, the ＂charal＂ fish Chirostoma spp. is grouped in five species： Chirostoma grandocule, Chirostoma ...The diversity of existing food may decrease malnutrition through the consumption of underutilized species. In Mexico, the ＂charal＂ fish Chirostoma spp. is grouped in five species： Chirostoma grandocule, Chirostoma patzcuaro, Chirostoma humboltianum, Chirostoma attenuatum and Chirostomajordani which live in lakes in the country, and they are not consumed or their demand is low The objective of this research was to analyze the macronutrients of Chirostomajordani charal and inform population their nutritional value to increase human nutrition. Sampling was provided at Xochimilco channels in Xochimilco, D.F., summer and winter seasons at 2009. Fish （200 g） were maintained in channels water for proximal analysis according AOAC methods （1995）. The results in dry bases were： protein 74.36%, lipids 1.24%, fiber 0.27%, minerals 4.9%, and soluble carbohydrates 19.23%. This fish grants protein, plastic material essential for human development： its lipid and carbohydrate contents, sources of energy, are low; however, the excess of disseminated proteins increase the energy sources. Fiber is found in a minimum amount. Dehydrated charales may be stored without refrigeration up to 3 months, maintaining their nutritional value. Consumption of the charal should be considered in the basic diet for its nutritional properties, to diminish malnutrition in the Mexico and other countries.展开更多
文摘Objective: To explore the levels of serum and ascitic fluid soluble tumor necrosis factor receptor-p55 (sTNFR-p55) and understand their clinical implication in primary hepatocellular carcinoma (HCC) patients. Methods: Enzyme-linked immunosorbent assay (ELISA) was used to examine the levels of sTNFR-p55 in the serum and ascitic fluid in 25 HCC patients and 25 patients with liver cirrhosis (LC). The test was also performed on the serum of 30 healthy subjects who served as control group. To assess the clinical effects of increased serum concentrations of sTNFR-p55, four parameters were analyzed by logistic regression. Results: Serum and ascitic fluid levels of sTNFR-p55 in HCC patients were significantly higher than those in LC patients and controls (P=0. 001). No significant difference was found between serum sTNFR-p55 levels in the latter 2 groups (P = 0. 19), and positive correlation between serum levels of sTNFR-p55 and that in ascitic fluid was noted in the 2 patient groups (r=1. 000, P<0. 001). Levels of the sTNFR-p55 positively correlated with TBIL and AFP in the peripheral blood of HCC patients (r=0. 524, P = 0. 01 and r=0. 234, P = 0. 03, respectively). Conclusion: Increased levels of sTNFRs-p55 in the serum and ascitic fluid could reflect the abnormal immune status of the HCC patients and may help predict the development of the tumor.
文摘The diversity of existing food may decrease malnutrition through the consumption of underutilized species. In Mexico, the ＂charal＂ fish Chirostoma spp. is grouped in five species： Chirostoma grandocule, Chirostoma patzcuaro, Chirostoma humboltianum, Chirostoma attenuatum and Chirostomajordani which live in lakes in the country, and they are not consumed or their demand is low The objective of this research was to analyze the macronutrients of Chirostomajordani charal and inform population their nutritional value to increase human nutrition. Sampling was provided at Xochimilco channels in Xochimilco, D.F., summer and winter seasons at 2009. Fish （200 g） were maintained in channels water for proximal analysis according AOAC methods （1995）. The results in dry bases were： protein 74.36%, lipids 1.24%, fiber 0.27%, minerals 4.9%, and soluble carbohydrates 19.23%. This fish grants protein, plastic material essential for human development： its lipid and carbohydrate contents, sources of energy, are low; however, the excess of disseminated proteins increase the energy sources. Fiber is found in a minimum amount. Dehydrated charales may be stored without refrigeration up to 3 months, maintaining their nutritional value. Consumption of the charal should be considered in the basic diet for its nutritional properties, to diminish malnutrition in the Mexico and other countries.
