Phytic acid (PA) is the primary storage compound of phosphorus in seeds accounting for up to 80% of the total seed phosphorus and contributing as much as 1.5% to the seed dry weight. The negatively charged phosphate i...Phytic acid (PA) is the primary storage compound of phosphorus in seeds accounting for up to 80% of the total seed phosphorus and contributing as much as 1.5% to the seed dry weight. The negatively charged phosphate in PA strongly binds to metallic cations of Ca, Fe, K, Mg, Mn and Zn making them insoluble and thus unavailable as nutritional factors. Phytate mainly accumulates in protein storage vacuoles as globoids, predominantly located in the aleurone layer (wheat, barley and rice) or in the embryo (maize). During germination, phytate is hydrolysed by endogenous phytase(s) and other phosphatases to release phosphate, inositol and micronutrients to support the emerging seedling. PA and its derivatives are also implicated in RNA export, DNA repair, signalling, endocytosis and cell vesicular trafficking. Our recent studies on purification of phytate globoids, their mineral composition and dephytinization by wheat phytase will be discussed. Biochemical data for purified and characterized phytases isolated from more than 23 plant species are presented, the dephosphorylation pathways of phytic acid by different classes of phytases are compared, and the application of phytase in food and feed is discussed.展开更多
Continuous and dynamic measurements of human respiratory parameters are very important for vital diseases of respiratory system during mechanical ventilation. This paper analyzed the structure and mechanical propertie...Continuous and dynamic measurements of human respiratory parameters are very important for vital diseases of respiratory system during mechanical ventilation. This paper analyzed the structure and mechanical properties of the human respiratory system, and designed an active intervening monitoring micro system for it. The mobile mechanism of the micro system is soft and earthworm-like movement actuated by pneumatic rubber actuator, the measurement and therapy unit of the system is an extensible mechanism with sensors in the front. The micro monitoring system can move in respiratory tract and measure the respiratory parameters in bronchium continuously. Experiments had been done in swine's respiratory tract, the results proved that the micro robot system could measure the respiratory parameters in real-time successfully and its movement was smith in swine's respiratory tract.展开更多
This study reviews the impacts of climate change on human health and presents corresponding adaptation strategies in South China. The daily mean surface air temperatures above or below 26.4~C increase the death risk f...This study reviews the impacts of climate change on human health and presents corresponding adaptation strategies in South China. The daily mean surface air temperatures above or below 26.4~C increase the death risk for people in Guangzhou, especially the elderly are vulnerable to variations in temperature. Heat waves can cause insomnia, fatigue, clinical exacerbation, or death from heatstroke etc., while cold spells show increases in patients with fractures. During a cold spell period, the rates of both on-site emergency rescues and non-implementable rescues increase, and the risk of non-accidental deaths and respiratory disease deaths significantly rise as well. Both time series of hazy days and ozone concentrations have significant positive correlations with the number of patients with cardiovascular diseases. Both malaria and dengue fever reach higher altitudes and mountainous areas due to climate warming. Climate change is likely to bring stronger heat waves in the future, thereby increasing heat wave-related illnesses and deaths, particularly in the metropolitan areas of the Pearl River Delta. The projected increase of consecutive cold days in Guangdong province and parts of northern Guangxi province will affect residents' health in the future. The rising temperature exaggerates ozone pollution, but it is not clear whether climate change is aggravating or mitigating haze pollution. The transmission potential of malaria in South China will increase by 39%-140% and the transmission season will extend by 1 2 months with an air temperature increase of 1-2~C. By 2050, most areas in Hainan province are projected to convert from non-endemic dengue into endemic dengue areas. The aging population will cause more vulnerable people. To mitigate the adverse impacts of climate change on human health, sound and scientific adaptation strategies must be adopted in advance, such as strengthening the surveillance of epidemic diseases in potential transmission areas, conducting timely weather forecasting for human health, evaluating health vulnerability to climate change, improving environmental and health education, and strengthening hazard management and the cooperation between meteorological and health departments.展开更多
Strict intraoperative glycemic control can significantly decrease the incidence of postoperative infection; however, anesthesiologists must carefully control blood glucose levels as well as properly manage the respira...Strict intraoperative glycemic control can significantly decrease the incidence of postoperative infection; however, anesthesiologists must carefully control blood glucose levels as well as properly manage the respiratory and cardiovascular systems. However, standard blood glucose measurement systems and insulin dosing algorithms, which are necessary for achieving strict glycemic control, have not yet been developed. An artificial pancreas (STG-22TM; Nikkiso Co., Tokyo, Japan) is considered a highly accurate blood glucose monitoring system capable of closed-loop control of blood glucose. The device has, however, many problems to be addressed since it is a large and expensive system with little versatility, and it requires a large amount of blood to be collected. Therefore, the development of less invasive and inexpensive systems with future technological progress is greatly anticipated.展开更多
The four-seasonal movement is the general movement of the universe. Galaxies, living beings, society, man-made worlds and all substances have or take part in the four-seasonal movement. There are transverse four-seaso...The four-seasonal movement is the general movement of the universe. Galaxies, living beings, society, man-made worlds and all substances have or take part in the four-seasonal movement. There are transverse four-seasonal movement and longitudinal four-seasonal movement. The former is the breathing movement. All substances have the function of breathing. Breathing involves living beings, celestial bodies, society and man-made systems and living beings of different levels have different ways of breathing. The longitudinal four-seasonal movement of living beings is controlled by genes. The four-seasonal movement is confined. Life originates in seeds and seeds are generated in the four-seasonal movement. Thoughts, ideas, designs and methods are the seeds of celestial bodies, society and man-made worlds. Just like living beings, galaxies, and society also have reproductive function. Reproduction has three major means: self-generation, generation by augmentation and generation by transformation. The reproduction of living beings is self-generation while the reproduction of the solar system and other galaxies is generation by augmentation. Man-made objects, society and galaxies are formed with automatic organization of thoughts, thus called generation by transformation. The solar system and the earth have reproduction function. Living beings began with the combined action of the earth, the solar system and the universe. Life forms of the universe include dominant life and recessive life. Different forms of life transform continuously.展开更多
基金Project supported by the Danish Agency for Science Technology andInnovation, Copenhagen,Denmark and HarvestPlus
文摘Phytic acid (PA) is the primary storage compound of phosphorus in seeds accounting for up to 80% of the total seed phosphorus and contributing as much as 1.5% to the seed dry weight. The negatively charged phosphate in PA strongly binds to metallic cations of Ca, Fe, K, Mg, Mn and Zn making them insoluble and thus unavailable as nutritional factors. Phytate mainly accumulates in protein storage vacuoles as globoids, predominantly located in the aleurone layer (wheat, barley and rice) or in the embryo (maize). During germination, phytate is hydrolysed by endogenous phytase(s) and other phosphatases to release phosphate, inositol and micronutrients to support the emerging seedling. PA and its derivatives are also implicated in RNA export, DNA repair, signalling, endocytosis and cell vesicular trafficking. Our recent studies on purification of phytate globoids, their mineral composition and dephytinization by wheat phytase will be discussed. Biochemical data for purified and characterized phytases isolated from more than 23 plant species are presented, the dephosphorylation pathways of phytic acid by different classes of phytases are compared, and the application of phytase in food and feed is discussed.
文摘Continuous and dynamic measurements of human respiratory parameters are very important for vital diseases of respiratory system during mechanical ventilation. This paper analyzed the structure and mechanical properties of the human respiratory system, and designed an active intervening monitoring micro system for it. The mobile mechanism of the micro system is soft and earthworm-like movement actuated by pneumatic rubber actuator, the measurement and therapy unit of the system is an extensible mechanism with sensors in the front. The micro monitoring system can move in respiratory tract and measure the respiratory parameters in bronchium continuously. Experiments had been done in swine's respiratory tract, the results proved that the micro robot system could measure the respiratory parameters in real-time successfully and its movement was smith in swine's respiratory tract.
基金supported by the Special Climate Change Research Program of China Meteorological Ad-ministration(No.CCSF-09-11 and CCSF201307)by the Science and Technology Planning Project of Guang-dong province(No.2011A030200021)
文摘This study reviews the impacts of climate change on human health and presents corresponding adaptation strategies in South China. The daily mean surface air temperatures above or below 26.4~C increase the death risk for people in Guangzhou, especially the elderly are vulnerable to variations in temperature. Heat waves can cause insomnia, fatigue, clinical exacerbation, or death from heatstroke etc., while cold spells show increases in patients with fractures. During a cold spell period, the rates of both on-site emergency rescues and non-implementable rescues increase, and the risk of non-accidental deaths and respiratory disease deaths significantly rise as well. Both time series of hazy days and ozone concentrations have significant positive correlations with the number of patients with cardiovascular diseases. Both malaria and dengue fever reach higher altitudes and mountainous areas due to climate warming. Climate change is likely to bring stronger heat waves in the future, thereby increasing heat wave-related illnesses and deaths, particularly in the metropolitan areas of the Pearl River Delta. The projected increase of consecutive cold days in Guangdong province and parts of northern Guangxi province will affect residents' health in the future. The rising temperature exaggerates ozone pollution, but it is not clear whether climate change is aggravating or mitigating haze pollution. The transmission potential of malaria in South China will increase by 39%-140% and the transmission season will extend by 1 2 months with an air temperature increase of 1-2~C. By 2050, most areas in Hainan province are projected to convert from non-endemic dengue into endemic dengue areas. The aging population will cause more vulnerable people. To mitigate the adverse impacts of climate change on human health, sound and scientific adaptation strategies must be adopted in advance, such as strengthening the surveillance of epidemic diseases in potential transmission areas, conducting timely weather forecasting for human health, evaluating health vulnerability to climate change, improving environmental and health education, and strengthening hazard management and the cooperation between meteorological and health departments.
文摘Strict intraoperative glycemic control can significantly decrease the incidence of postoperative infection; however, anesthesiologists must carefully control blood glucose levels as well as properly manage the respiratory and cardiovascular systems. However, standard blood glucose measurement systems and insulin dosing algorithms, which are necessary for achieving strict glycemic control, have not yet been developed. An artificial pancreas (STG-22TM; Nikkiso Co., Tokyo, Japan) is considered a highly accurate blood glucose monitoring system capable of closed-loop control of blood glucose. The device has, however, many problems to be addressed since it is a large and expensive system with little versatility, and it requires a large amount of blood to be collected. Therefore, the development of less invasive and inexpensive systems with future technological progress is greatly anticipated.
文摘The four-seasonal movement is the general movement of the universe. Galaxies, living beings, society, man-made worlds and all substances have or take part in the four-seasonal movement. There are transverse four-seasonal movement and longitudinal four-seasonal movement. The former is the breathing movement. All substances have the function of breathing. Breathing involves living beings, celestial bodies, society and man-made systems and living beings of different levels have different ways of breathing. The longitudinal four-seasonal movement of living beings is controlled by genes. The four-seasonal movement is confined. Life originates in seeds and seeds are generated in the four-seasonal movement. Thoughts, ideas, designs and methods are the seeds of celestial bodies, society and man-made worlds. Just like living beings, galaxies, and society also have reproductive function. Reproduction has three major means: self-generation, generation by augmentation and generation by transformation. The reproduction of living beings is self-generation while the reproduction of the solar system and other galaxies is generation by augmentation. Man-made objects, society and galaxies are formed with automatic organization of thoughts, thus called generation by transformation. The solar system and the earth have reproduction function. Living beings began with the combined action of the earth, the solar system and the universe. Life forms of the universe include dominant life and recessive life. Different forms of life transform continuously.