To analyze the use of upper limb support during paraplegic walking assisted by functional electrical stimulation ( FES), a new dynamical measurement for handle reaction vector (HRV) ap- plied by patient to walker was ...To analyze the use of upper limb support during paraplegic walking assisted by functional electrical stimulation ( FES), a new dynamical measurement for handle reaction vector (HRV) ap- plied by patient to walker was proposed. To avoid the discomfort of direct monitoring, the dyna- mometer system was designed based on 12 string-gauge bridges instrumented on a standard walker frame. The detailed positions of these bridges were determined according to the deformation distri- butions of the walker frame under different directional components of HRV. To adapt the system to quantitative and reliable measurement, a redundant-optimized technique was developed in calibra- tion. The measurement accuracy, nonlinearity. and crosstalk of the designed system were investi- gated, which were better than 1.01%. 2.91%, and 3.19% respectively. Clinical trials were done with 6 paraplegic subjects using the system and one case was given as the example of actual mea- surement. All experiment and clinical trial results show that this method is reliable and practicable.展开更多
Retinal degenerative diseases may induce the degeneration of outer retina and in turn,blindness.Nevertheless,due to the maintenance of inner retina,the coding and processing of visual neurons responses are still able ...Retinal degenerative diseases may induce the degeneration of outer retina and in turn,blindness.Nevertheless,due to the maintenance of inner retina,the coding and processing of visual neurons responses are still able to be executed naturally.Therefore,an effective retinal prosthesis device may be developed by mimicking the function of outer retina:transferring the visual light into artificial stimulus and delivering the stimulus to the retina aiming to evoke the neural responses.As two main developing directions for current retinal prosthesis,epiretinal(ER)and subretinal(SR)prosthesis are both undergoing experimental stage and possessing advantages and limitations.Further investigations in power supply,biocompatibility,etc.are still required.Additionally,suprachoroidal transretinal stimulation(STS)and neurotransmitter-induced stimulation as some other alternatives in retinal prosthesis are also considered as promising research directions,although they are not mature enough to be applied commercially,either.展开更多
The ideal animal stimulus is under total control of the experimenter,has visual traits, and behavior patterns that can be varied in anyway, and it appears and behaves consistently between test trials thatcan be easily...The ideal animal stimulus is under total control of the experimenter,has visual traits, and behavior patterns that can be varied in anyway, and it appears and behaves consistently between test trials thatcan be easily repeated many times and any time. Does this soundlike wishful thinking of a biologist? Using and exploiting the poten-tial of artificial stimuli in animal behavior research is actually not anew idea.展开更多
基金Supported by China Postdoctoral Science Foundation( No. 2004036135) and Tianjin Key Project Fund( No. 2000-31).
文摘To analyze the use of upper limb support during paraplegic walking assisted by functional electrical stimulation ( FES), a new dynamical measurement for handle reaction vector (HRV) ap- plied by patient to walker was proposed. To avoid the discomfort of direct monitoring, the dyna- mometer system was designed based on 12 string-gauge bridges instrumented on a standard walker frame. The detailed positions of these bridges were determined according to the deformation distri- butions of the walker frame under different directional components of HRV. To adapt the system to quantitative and reliable measurement, a redundant-optimized technique was developed in calibra- tion. The measurement accuracy, nonlinearity. and crosstalk of the designed system were investi- gated, which were better than 1.01%. 2.91%, and 3.19% respectively. Clinical trials were done with 6 paraplegic subjects using the system and one case was given as the example of actual mea- surement. All experiment and clinical trial results show that this method is reliable and practicable.
文摘Retinal degenerative diseases may induce the degeneration of outer retina and in turn,blindness.Nevertheless,due to the maintenance of inner retina,the coding and processing of visual neurons responses are still able to be executed naturally.Therefore,an effective retinal prosthesis device may be developed by mimicking the function of outer retina:transferring the visual light into artificial stimulus and delivering the stimulus to the retina aiming to evoke the neural responses.As two main developing directions for current retinal prosthesis,epiretinal(ER)and subretinal(SR)prosthesis are both undergoing experimental stage and possessing advantages and limitations.Further investigations in power supply,biocompatibility,etc.are still required.Additionally,suprachoroidal transretinal stimulation(STS)and neurotransmitter-induced stimulation as some other alternatives in retinal prosthesis are also considered as promising research directions,although they are not mature enough to be applied commercially,either.
文摘The ideal animal stimulus is under total control of the experimenter,has visual traits, and behavior patterns that can be varied in anyway, and it appears and behaves consistently between test trials thatcan be easily repeated many times and any time. Does this soundlike wishful thinking of a biologist? Using and exploiting the poten-tial of artificial stimuli in animal behavior research is actually not anew idea.