Postoperative hyperglycemia is common in critically ill patients, even in those without a prior history of diabetes mellitus. It is well known that hyperglycemia induced by surgical stress often results in dysregulati...Postoperative hyperglycemia is common in critically ill patients, even in those without a prior history of diabetes mellitus. It is well known that hyperglycemia induced by surgical stress often results in dysregulation of liver metabolism and immune function, impairing postoperative recovery. Current evidence suggests that maintaining normoglycemia postoperatively improves surgical outcome and reduces the mortality and morbidity of critically ill patients. On the basis of these observations, several large randomized controlled studies were designed to evaluate the benefit of postoperative tight glycemic control with intensive insulin therapy. However, intensive insulin therapy carries the risk of hypoglycemia, which is linked to serious neurological events. Recently, we demonstrated that perioperative tight glycemic control in surgical patients could be achieved safely using a closed-loop glycemic control system and that this decreased both the incidence of infection at the site of the surgical incision, without the appearance of hypoglycemia, and actual hospital costs. Here, we review the benefits and requirements of perioperative intensive insulin therapy using a dosed-loop artificial endocrine pancreas system in hepatectomized patients. This novel intensive insulin therapy is safe and effectively improves surgical outcome after hepatic resection.展开更多
The growth of reeds was impeded remarkably under a salinity of 15.0±3.4 g CI·L-1 in the first year of this experiment, recovered in the second year and then increased year-by-year afterward. The growth of re...The growth of reeds was impeded remarkably under a salinity of 15.0±3.4 g CI·L-1 in the first year of this experiment, recovered in the second year and then increased year-by-year afterward. The growth of reeds under a salinity of 9.3±1.9 g CI·Ll was much better than those under 15.0 ± 3.4 g CI·L1. The stress effect was significant for shoot extension but not for the quantity of shoots increase. The dense vegetation bed during the vegetation period （June-October） provided a high rate of evapotranspiration and water loss from HFs （horizontal subsurface flow constructed wetlands）, which made large contributions to reducing pollutant load. The HFs with die-back reeds in the non-vegetation periods （November-March） provided slight evapotranspiration and water loss and made less of a contribution to reducing pollutants removal compared to HFs with the dense vegetation bed in the vegetation periods. However, the HFs with die-back reeds in the non-vegetation periods had higher removal performance than the HF without reeds. This indicated that the rhizosphere of HFs with reeds might play important roles, such as that the microbes around rhizomes might have a higher amount of pollutant-removing microbe activity than those in the HF without reeds during the non-vegetation period.展开更多
文摘Postoperative hyperglycemia is common in critically ill patients, even in those without a prior history of diabetes mellitus. It is well known that hyperglycemia induced by surgical stress often results in dysregulation of liver metabolism and immune function, impairing postoperative recovery. Current evidence suggests that maintaining normoglycemia postoperatively improves surgical outcome and reduces the mortality and morbidity of critically ill patients. On the basis of these observations, several large randomized controlled studies were designed to evaluate the benefit of postoperative tight glycemic control with intensive insulin therapy. However, intensive insulin therapy carries the risk of hypoglycemia, which is linked to serious neurological events. Recently, we demonstrated that perioperative tight glycemic control in surgical patients could be achieved safely using a closed-loop glycemic control system and that this decreased both the incidence of infection at the site of the surgical incision, without the appearance of hypoglycemia, and actual hospital costs. Here, we review the benefits and requirements of perioperative intensive insulin therapy using a dosed-loop artificial endocrine pancreas system in hepatectomized patients. This novel intensive insulin therapy is safe and effectively improves surgical outcome after hepatic resection.
文摘The growth of reeds was impeded remarkably under a salinity of 15.0±3.4 g CI·L-1 in the first year of this experiment, recovered in the second year and then increased year-by-year afterward. The growth of reeds under a salinity of 9.3±1.9 g CI·Ll was much better than those under 15.0 ± 3.4 g CI·L1. The stress effect was significant for shoot extension but not for the quantity of shoots increase. The dense vegetation bed during the vegetation period （June-October） provided a high rate of evapotranspiration and water loss from HFs （horizontal subsurface flow constructed wetlands）, which made large contributions to reducing pollutant load. The HFs with die-back reeds in the non-vegetation periods （November-March） provided slight evapotranspiration and water loss and made less of a contribution to reducing pollutants removal compared to HFs with the dense vegetation bed in the vegetation periods. However, the HFs with die-back reeds in the non-vegetation periods had higher removal performance than the HF without reeds. This indicated that the rhizosphere of HFs with reeds might play important roles, such as that the microbes around rhizomes might have a higher amount of pollutant-removing microbe activity than those in the HF without reeds during the non-vegetation period.
