Anthropogenic aluminum cycle in China was analyzed by the aluminum flow diagram based on the life cycle of aluminum products. The whole anthropogenic aluminum cycle consists of four stages： alumina and aluminum produ...Anthropogenic aluminum cycle in China was analyzed by the aluminum flow diagram based on the life cycle of aluminum products. The whole anthropogenic aluminum cycle consists of four stages： alumina and aluminum production, fabrication and manufacture, use and reclamation. Based on the investigation on the 2003-2007 aluminum cycles in China, a number of changes can be found. For instance, resources self-support ratio （RSR） in alumina production dropped from 95.42%to 55.50%, while RSR in the aluminum production increased from 52.45%to 79.25%. However, RSR in the Chinese aluminum industry leveled off at 50%in the period of 2003-2007. The respective use ratios of domestic and imported aluminum scrap in the aluminum industry of 2007 were 5.38% and 9.40%. In contrast, both the net imported Al-containing resources and the lost quantity of Al-containing materials in aluminum cycle increased during the same period, as well as the net increased quantity of Al-containing materials in social stock and recycled Al-scrap. Proposals for promoting aluminum cycle were put forward. The import/export policy and reducing the loss of Al-containing materials for the aluminum industry in China in the future were discussed.展开更多
Knowledge of the changes in a material’s function, form, and location during the transfer and transformation of materials to generate human services will improve our understanding of how humanity interacts with the e...Knowledge of the changes in a material’s function, form, and location during the transfer and transformation of materials to generate human services will improve our understanding of how humanity interacts with the environment and of how services are formed by human activities. We compared lead’s anthropogenic and biogeochemical cycles and found that the services, pathways, and changes in form requiring the most attention. We traced lead through its life cycle and identified the changes in its functions, forms, and locations by examining technology and engineering information. Lead ore and scrap were the two main anthropogenic sources of lead. When lead provides human services, its main functions included the storage and delivery of electricity, anti-corrosion treatments, and radiation protection; the main forms of lead in these products were Pb, PbO2 and PbSO4, and the main location changed from lithosphere in central China to regions in eastern China.展开更多
In recent years, the incidence of placenta previa has been increasing. According to the literature, it is mainly related to induced labor, artificial abortion, cesarean section, high aging pregnancy, multipara or smok...In recent years, the incidence of placenta previa has been increasing. According to the literature, it is mainly related to induced labor, artificial abortion, cesarean section, high aging pregnancy, multipara or smoking. The placenta previa is the chief cause of bleeding in late pregnancy and threatens the lives of mother and infant, resulting in a high risk problem in obstetrics. This article studies 322 cases of placenta previa from my hospital and Dalian Obstetrics and Gynecological Hospital from January, 2002 to July, 2009, on the basis of clinicretrospective analysis, in order to deepen our understanding and art of treating placenta previa. The study revealed that: 1. With 322 cases of placenta previa, the incidence was 0.73%. It was higher than the incidence 0.3% reported abroad and lower than the incidence 0.94% reported in our country. The data were from sampling survey and did not prove relations between placenta previa and ages, different from the result obtained abroad in which placenta previa had relation with pregnancy ages. The outcome needs further study. But artificial abortion, induced labor, cesarean section and multipara clearly influence the incidence. The study did not analyze the relation between smoking and placenta previa, but there was external data proving that smoking was related to placenta previa; 2. Ultrasound-B is a better method for examination at present; 3. In cases of vaginal childbirth there was a higher incidence of lateral placenta previa and partial placenta previa. The conservative temporization and timely cesarean section can greatly decrease the mortality of mother and infant.展开更多
Objective： The aim of the study was to investigate the apoptosis induced by piperlongumine on human breast adenoma MDA-MB-231 cells and the mechanism involved. Methods： Human breast adenoma MDA-MB-231 cells line was...Objective： The aim of the study was to investigate the apoptosis induced by piperlongumine on human breast adenoma MDA-MB-231 cells and the mechanism involved. Methods： Human breast adenoma MDA-MB-231 cells line was cultured in vitro. The inhibitory effect of piperlongumine on the proliferation of human breast adenoma MDA-MB-231 cells was measured by CCK-8 assay. Distribution of cell cycle was analyzed by flow cytometry. The apoptosis rates of MDA-MB- 231 cells were measured using Annexin V/PI staining. The flow cytometry with the probe of DCFH-DA was used to detect the intracellular reactive oxygen species levels. Western blot was used to explore the protein expression of Bcl-2 and Bax. Results： The CCK-8 assay showed that piperlongumine had an inhibiting effect on the proliferation of MDA-MB-231 cells in a concentrationand time-dependent manner. MDA-MB-231 cells were markedly arrested at G0/G1 phase after treatment of piperlongumine. Piperlongumine induced apoptosis of MDA-MB-231 cells obviously. The level of intracellular reactive oxygen species was increased in a dose-dependent manner. The antioxidant N-acetyI-L-cystein inhibited the apoptosis of cells and the level of intracellular reactive oxygen species was also decreased. By Western blot analysis, we found the expression of Bax was up-regulated whereas that of Bcl-2 was down-regulated in a concentration-dependent manner. Conclusion： PiperIongumine possesses a significant function for inhibiting proliferation, arresting cells at G0/G1 phase and inducing apoptosis of MDA-MB-231 cells, which seems to be associated with the increased generation of intracellular reactive oxygen species as well as the down-regulation of Bcl-2 and up-regulation of Bax.展开更多
Worldwide women have to cope up with heavy burden of unwanted pregnancies, mistimed, unplanned, with risk to their health. Their children and families also suf-fer. Such pregnancies are root cause of induced abortions...Worldwide women have to cope up with heavy burden of unwanted pregnancies, mistimed, unplanned, with risk to their health. Their children and families also suf-fer. Such pregnancies are root cause of induced abortions （safe/unsafe） and grave consequences. Women, their partners can, for most part, prevent unwanted pregnancies by using contraceptives. However many women either do not use any contraceptive or use methods, with high failure rates. These women account for 82% of pregnancies that are not desired. Remaining unintended pregnancies occur among women who use modern contraceptive, either because they had diffculty using method consistently or because of failure. Helping women, their partner use modern contracep-tives effectively is essential in achieving Millennium Development Goals for improving women’s health, reducing poverty. If all women in developing countries use modern contraceptives, there would be 22 million less unplanned births, 25 million fewer induced, 15 million fewer unsafe abortions, 90000 less maternal deaths and 390000 less children losing their mothers. Also making abortion services broadly legal, by understand-ing size, type of unmet needs, most important by creating awareness in communities can surely help tackle this problem to a large extent.展开更多
基金Projects (71003018,71373003) supported by the National Natural Science Foundation of ChinaProjects (N110402003,N120302004) supported by the Fundamental Research Funds for the Central Universities,ChinaProject (13YJCZH172) supported by the Ministry of Education of China of Humanities and Social Sciences
文摘Anthropogenic aluminum cycle in China was analyzed by the aluminum flow diagram based on the life cycle of aluminum products. The whole anthropogenic aluminum cycle consists of four stages： alumina and aluminum production, fabrication and manufacture, use and reclamation. Based on the investigation on the 2003-2007 aluminum cycles in China, a number of changes can be found. For instance, resources self-support ratio （RSR） in alumina production dropped from 95.42%to 55.50%, while RSR in the aluminum production increased from 52.45%to 79.25%. However, RSR in the Chinese aluminum industry leveled off at 50%in the period of 2003-2007. The respective use ratios of domestic and imported aluminum scrap in the aluminum industry of 2007 were 5.38% and 9.40%. In contrast, both the net imported Al-containing resources and the lost quantity of Al-containing materials in aluminum cycle increased during the same period, as well as the net increased quantity of Al-containing materials in social stock and recycled Al-scrap. Proposals for promoting aluminum cycle were put forward. The import/export policy and reducing the loss of Al-containing materials for the aluminum industry in China in the future were discussed.
基金Project(41171361)supported by the National Natural Science Foundation of China(General Program)
文摘Knowledge of the changes in a material’s function, form, and location during the transfer and transformation of materials to generate human services will improve our understanding of how humanity interacts with the environment and of how services are formed by human activities. We compared lead’s anthropogenic and biogeochemical cycles and found that the services, pathways, and changes in form requiring the most attention. We traced lead through its life cycle and identified the changes in its functions, forms, and locations by examining technology and engineering information. Lead ore and scrap were the two main anthropogenic sources of lead. When lead provides human services, its main functions included the storage and delivery of electricity, anti-corrosion treatments, and radiation protection; the main forms of lead in these products were Pb, PbO2 and PbSO4, and the main location changed from lithosphere in central China to regions in eastern China.
文摘In recent years, the incidence of placenta previa has been increasing. According to the literature, it is mainly related to induced labor, artificial abortion, cesarean section, high aging pregnancy, multipara or smoking. The placenta previa is the chief cause of bleeding in late pregnancy and threatens the lives of mother and infant, resulting in a high risk problem in obstetrics. This article studies 322 cases of placenta previa from my hospital and Dalian Obstetrics and Gynecological Hospital from January, 2002 to July, 2009, on the basis of clinicretrospective analysis, in order to deepen our understanding and art of treating placenta previa. The study revealed that: 1. With 322 cases of placenta previa, the incidence was 0.73%. It was higher than the incidence 0.3% reported abroad and lower than the incidence 0.94% reported in our country. The data were from sampling survey and did not prove relations between placenta previa and ages, different from the result obtained abroad in which placenta previa had relation with pregnancy ages. The outcome needs further study. But artificial abortion, induced labor, cesarean section and multipara clearly influence the incidence. The study did not analyze the relation between smoking and placenta previa, but there was external data proving that smoking was related to placenta previa; 2. Ultrasound-B is a better method for examination at present; 3. In cases of vaginal childbirth there was a higher incidence of lateral placenta previa and partial placenta previa. The conservative temporization and timely cesarean section can greatly decrease the mortality of mother and infant.
基金Supported by grants from the Priority Academic Program Development of Jiangsu Higher Education Institutions (No. JX10231801)the Innovative Medical Team and Leading Talent of Jiangsu Province (No. LJ201123)
文摘Objective： The aim of the study was to investigate the apoptosis induced by piperlongumine on human breast adenoma MDA-MB-231 cells and the mechanism involved. Methods： Human breast adenoma MDA-MB-231 cells line was cultured in vitro. The inhibitory effect of piperlongumine on the proliferation of human breast adenoma MDA-MB-231 cells was measured by CCK-8 assay. Distribution of cell cycle was analyzed by flow cytometry. The apoptosis rates of MDA-MB- 231 cells were measured using Annexin V/PI staining. The flow cytometry with the probe of DCFH-DA was used to detect the intracellular reactive oxygen species levels. Western blot was used to explore the protein expression of Bcl-2 and Bax. Results： The CCK-8 assay showed that piperlongumine had an inhibiting effect on the proliferation of MDA-MB-231 cells in a concentrationand time-dependent manner. MDA-MB-231 cells were markedly arrested at G0/G1 phase after treatment of piperlongumine. Piperlongumine induced apoptosis of MDA-MB-231 cells obviously. The level of intracellular reactive oxygen species was increased in a dose-dependent manner. The antioxidant N-acetyI-L-cystein inhibited the apoptosis of cells and the level of intracellular reactive oxygen species was also decreased. By Western blot analysis, we found the expression of Bax was up-regulated whereas that of Bcl-2 was down-regulated in a concentration-dependent manner. Conclusion： PiperIongumine possesses a significant function for inhibiting proliferation, arresting cells at G0/G1 phase and inducing apoptosis of MDA-MB-231 cells, which seems to be associated with the increased generation of intracellular reactive oxygen species as well as the down-regulation of Bcl-2 and up-regulation of Bax.
文摘Worldwide women have to cope up with heavy burden of unwanted pregnancies, mistimed, unplanned, with risk to their health. Their children and families also suf-fer. Such pregnancies are root cause of induced abortions （safe/unsafe） and grave consequences. Women, their partners can, for most part, prevent unwanted pregnancies by using contraceptives. However many women either do not use any contraceptive or use methods, with high failure rates. These women account for 82% of pregnancies that are not desired. Remaining unintended pregnancies occur among women who use modern contraceptive, either because they had diffculty using method consistently or because of failure. Helping women, their partner use modern contracep-tives effectively is essential in achieving Millennium Development Goals for improving women’s health, reducing poverty. If all women in developing countries use modern contraceptives, there would be 22 million less unplanned births, 25 million fewer induced, 15 million fewer unsafe abortions, 90000 less maternal deaths and 390000 less children losing their mothers. Also making abortion services broadly legal, by understand-ing size, type of unmet needs, most important by creating awareness in communities can surely help tackle this problem to a large extent.
