目的小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法采用平滑非线性能量算子(smoothed nonlinear ...目的小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法采用平滑非线性能量算子(smoothed nonlinear energy operator,SNEO)算法,对痉挛型脑瘫患儿表面肌电信号中的运动单位动作电位(motor unit action potential,MUAP)数目进行估计,获得MUAP的平均发放间隔(inter-pulse interval,IPI),并根据医生采用的分级结果和健康人MUAP平均发放时限的早期研究结果进行对比验证。结果对14名不同运动障碍级别脑瘫患者的实验结果显示,其肌电信号MUAP的IPI与他们活动度的级别即运动障碍的程度呈正相关的关系,且具有明显差异。结论研究结果表明本文方法有效,采用IPI参数能够反映脑瘫患儿的运动障碍程度。展开更多
Objective: To study the generator sites of spontaneous discharges in patients with immune-mediated neuromyotonia. Methods: Macro EMGs triggered by both spontaneously and voluntarily activated single action potentials ...Objective: To study the generator sites of spontaneous discharges in patients with immune-mediated neuromyotonia. Methods: Macro EMGs triggered by both spontaneously and voluntarily activated single action potentials were recorded and the mean peak-to-peak amplitude and area of the macro motor unit potentials were compared in two patients with typical acquired neuromyotonia having positive antibodies against voltage-gated potassium channels. Results: Mean peak-to-peak amplitude and area of Macro EMG motor unit potentials (macro MUPs) triggered by spontaneous discharges were significantly smaller than those triggered by voluntary activation in both patients. However, a few macro MUPs triggered by spontaneous discharges resembled those triggered by voluntary activation. Conclusions: Spontaneous discharges in two patients with immune-mediated neuromyotonia seem to be mostly generated at sites distal to the terminal axon branching points. Significance: This finding may provide a new insight in the understanding of spontaneous discharges in immune-mediated neuromyotonia.展开更多
文摘目的小儿脑瘫患者的运动障碍分级和康复评估具有重要的临床价值。本文利用表面肌电信号对痉挛型脑瘫患儿的运动神经元发放特性进行研究,旨在为脑瘫患儿的运动障碍评估提供一种量化指标。方法采用平滑非线性能量算子(smoothed nonlinear energy operator,SNEO)算法,对痉挛型脑瘫患儿表面肌电信号中的运动单位动作电位(motor unit action potential,MUAP)数目进行估计,获得MUAP的平均发放间隔(inter-pulse interval,IPI),并根据医生采用的分级结果和健康人MUAP平均发放时限的早期研究结果进行对比验证。结果对14名不同运动障碍级别脑瘫患者的实验结果显示,其肌电信号MUAP的IPI与他们活动度的级别即运动障碍的程度呈正相关的关系,且具有明显差异。结论研究结果表明本文方法有效,采用IPI参数能够反映脑瘫患儿的运动障碍程度。
文摘Objective: To study the generator sites of spontaneous discharges in patients with immune-mediated neuromyotonia. Methods: Macro EMGs triggered by both spontaneously and voluntarily activated single action potentials were recorded and the mean peak-to-peak amplitude and area of the macro motor unit potentials were compared in two patients with typical acquired neuromyotonia having positive antibodies against voltage-gated potassium channels. Results: Mean peak-to-peak amplitude and area of Macro EMG motor unit potentials (macro MUPs) triggered by spontaneous discharges were significantly smaller than those triggered by voluntary activation in both patients. However, a few macro MUPs triggered by spontaneous discharges resembled those triggered by voluntary activation. Conclusions: Spontaneous discharges in two patients with immune-mediated neuromyotonia seem to be mostly generated at sites distal to the terminal axon branching points. Significance: This finding may provide a new insight in the understanding of spontaneous discharges in immune-mediated neuromyotonia.
