In order to study the scale characteristics of heterogeneities in complex media, a random medium is constructed using a statistical method and by changing model parameters （autocorrelation lengths a and b）, the scal...In order to study the scale characteristics of heterogeneities in complex media, a random medium is constructed using a statistical method and by changing model parameters （autocorrelation lengths a and b）, the scales of heterogeneous geologic bodies in the horizontal and the vertical Cartesian directions may be varied in the medium. The autocorrelation lengths a and b represent the mean scale of heterogeneous geologic bodies in the horizontal and vertical Cartesian directions in the randQm medium, respectively. Based on this model, the relationship between model autocorrelation lengths and heterogeneous geologic body scales is studied by horizontal velocity variation and standard deviation. The horizontal velocity variation research shows that velocities are in random perturbation. The heterogeneous geologic body scale increases with increasing autocorrelation length. The recursion equation for the relationship between autocorrelation lengths and heterogeneous geologic body scales is determined from the velocity standard deviation research and the actual heterogeneous geologic body scale magnitude can be estimated by the equation.展开更多
A filed experiment was conducted continuously for three days,and the velocity variation was measured using coda wave interferometry.The measurement error is estimated to be around 10-4,which coincides well with the th...A filed experiment was conducted continuously for three days,and the velocity variation was measured using coda wave interferometry.The measurement error is estimated to be around 10-4,which coincides well with the theoretical error.The velocity variation during this period is up to 10-3.The relationship between velocity variation and changes in air temperature,barometric pressure and solid earth tide was analyzed with linear least square fitting.The velocity has no dependence on air temperature,but displayed change of the order of 10-6～10-7 when the barometer or earth tide changed one Pa.展开更多
Monte Carlo simulation of the diffusing temporal light correlation in a multi-layered turbid medium is considered.A straightforward formula is introduced to calculate accurately and efficiently the autocorrelation fun...Monte Carlo simulation of the diffusing temporal light correlation in a multi-layered turbid medium is considered.A straightforward formula is introduced to calculate accurately and efficiently the autocorrelation function at any detector position.The simulation results are in an excellent agreement with an analytical solution of the correlation diffusion equation.展开更多
综述具有生物相关性的溶出度方法,以通过理想的体外溶出试验预测体内药动学过程。近年来,研究表明在生物相关性溶出介质中选择合适的溶出装置进行溶出试验得到的溶出曲线能较好地反映其在体内的溶出行为,计算机模拟软件可为建立合理的...综述具有生物相关性的溶出度方法,以通过理想的体外溶出试验预测体内药动学过程。近年来,研究表明在生物相关性溶出介质中选择合适的溶出装置进行溶出试验得到的溶出曲线能较好地反映其在体内的溶出行为,计算机模拟软件可为建立合理的体外溶出度方法提供指导和依据。通过采用合适的生物相关性溶出介质、溶出装置,结合计算机模拟软件可建立A级水平的体内外相关性(in vitro-in vivo correlation,IVIVC),可能代替生物等效性研究。展开更多
基金sponsored by the 973 Program (No. 2009CB219505)the Talents Introduction Special Project of Guangdong Ocean University (No. 0812182)
文摘In order to study the scale characteristics of heterogeneities in complex media, a random medium is constructed using a statistical method and by changing model parameters （autocorrelation lengths a and b）, the scales of heterogeneous geologic bodies in the horizontal and the vertical Cartesian directions may be varied in the medium. The autocorrelation lengths a and b represent the mean scale of heterogeneous geologic bodies in the horizontal and vertical Cartesian directions in the randQm medium, respectively. Based on this model, the relationship between model autocorrelation lengths and heterogeneous geologic body scales is studied by horizontal velocity variation and standard deviation. The horizontal velocity variation research shows that velocities are in random perturbation. The heterogeneous geologic body scale increases with increasing autocorrelation length. The recursion equation for the relationship between autocorrelation lengths and heterogeneous geologic body scales is determined from the velocity standard deviation research and the actual heterogeneous geologic body scale magnitude can be estimated by the equation.
基金sponsored by the Special R & D Project of China Earthquake Administration(200808002)the Special Project of Basic Scientific Research of the Institute of Geophysics,CEA(DQJB08B13)
文摘A filed experiment was conducted continuously for three days,and the velocity variation was measured using coda wave interferometry.The measurement error is estimated to be around 10-4,which coincides well with the theoretical error.The velocity variation during this period is up to 10-3.The relationship between velocity variation and changes in air temperature,barometric pressure and solid earth tide was analyzed with linear least square fitting.The velocity has no dependence on air temperature,but displayed change of the order of 10-6～10-7 when the barometer or earth tide changed one Pa.
文摘Monte Carlo simulation of the diffusing temporal light correlation in a multi-layered turbid medium is considered.A straightforward formula is introduced to calculate accurately and efficiently the autocorrelation function at any detector position.The simulation results are in an excellent agreement with an analytical solution of the correlation diffusion equation.
文摘综述具有生物相关性的溶出度方法,以通过理想的体外溶出试验预测体内药动学过程。近年来,研究表明在生物相关性溶出介质中选择合适的溶出装置进行溶出试验得到的溶出曲线能较好地反映其在体内的溶出行为,计算机模拟软件可为建立合理的体外溶出度方法提供指导和依据。通过采用合适的生物相关性溶出介质、溶出装置,结合计算机模拟软件可建立A级水平的体内外相关性(in vitro-in vivo correlation,IVIVC),可能代替生物等效性研究。
